4-Phenyl-1H-imidazole-2-carbaldehyde
- Product Name
- 4-Phenyl-1H-imidazole-2-carbaldehyde
- CAS No.
- 56248-10-3
- Chemical Name
- 4-Phenyl-1H-imidazole-2-carbaldehyde
- Synonyms
- 4-Phenylimidazole-2-carbaldehyde;4-Phenyl-1H-imidazole-2-carbaldehyde;5-Phenyl-1H-imidazole-2-carbaldehyde;1H-IMidazole-2-carboxaldehyde,4-phenyl;1H-Imidazole-2-carboxaldehyde, 5-phenyl-
- CBNumber
- CB22282989
- Molecular Formula
- C10H8N2O
- Formula Weight
- 172.18
- MOL File
- 56248-10-3.mol
4-Phenyl-1H-imidazole-2-carbaldehyde Property
- Boiling point:
- 415.8±38.0 °C(Predicted)
- Density
- 1.248±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 11.17±0.10(Predicted)
- Appearance
- Light yellow to brown Solid
- InChI
- InChI=1S/C10H8N2O/c13-7-10-11-6-9(12-10)8-4-2-1-3-5-8/h1-7H,(H,11,12)
- InChIKey
- OIZJTDJQBZIIAH-UHFFFAOYSA-N
- SMILES
- C1(C=O)NC(C2=CC=CC=C2)=CN=1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P322098
- Product name
- 4-phenyl-1H-imidazole-2-carbaldehyde
- Packaging
- 50mg
- Price
- $350
- Updated
- 2021/12/16
- Product number
- CHM1049165
- Product name
- 4-PHENYL-1H-IMIDAZOLE-2-CARBALDEHYDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.62
- Updated
- 2021/12/16
- Product number
- 8332BA
- Product name
- 5-Phenyl-1H-imidazole-2-carbaldehyde
- Packaging
- 100mg
- Price
- $282
- Updated
- 2021/12/16
- Product number
- CD11103897
- Product name
- 5-Phenyl-1H-imidazole-2-carbaldehyde
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $309
- Updated
- 2021/12/16
- Product number
- A138914
- Product name
- 5-Phenyl-1H-imidazole-2-carbaldehyde
- Purity
- 95%
- Packaging
- 100mg
- Price
- $165
- Updated
- 2021/12/16
4-Phenyl-1H-imidazole-2-carbaldehyde Chemical Properties,Usage,Production
Synthesis
51673-84-8
1074-12-0
56248-10-3
The general procedure for the synthesis of 4-phenyl-1(3)H-imidazole-2-carboxaldehyde from glyoxal dimethyl acetal and phenylpropanol hydrate was as follows: phenylglyoxal monohydrate (102 g, 0.67 mol) and glyoxal dimethyl acetal (60% aqueous solution, 232 mL, 1.54 mol) were dissolved in methanol (1.1 L), followed by the addition of ammonium acetate (820 g 2.61 mol) to the methanol solution (1.1 L). The reaction mixture was stirred at room temperature for 16 hours. Upon completion of the reaction, the volatile solvent was removed by distillation under reduced pressure. The residue was suspended in 2N HCl solution (1.1 L) and heated at 80 °C for 30 min. After cooling, the reaction mixture was extracted with EtOAc (200 mL). The aqueous layer was separated and adjusted to pH 9 with 9N NaOH solution. the precipitated solid was filtered, washed with water and dried under vacuum to afford 4-phenyl-1(3)H-imidazole-2-carboxaldehyde (97.2 g, 84% yield) as a light brown solid. the LC-MS analysis resulted in: m/z = 173.0 (MH+), and the retention time tR = 0.66 min (Method C). the reaction was carried out at a pressure of 1.5 mL. the reaction mixture was extracted with EtOAc (200 mL).
References
[1] Patent: US2010/16303, 2010, A1. Location in patent: Page/Page column 19
[2] Patent: WO2012/7006, 2012, A1. Location in patent: Page/Page column 60
[3] Patent: WO2009/152825, 2009, A1. Location in patent: Page/Page column 46
4-Phenyl-1H-imidazole-2-carbaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Phenyl-1H-imidazole-2-carbaldehyde manufacturers
- Product
- 4-Phenyl-1H-imidazole-2-carbaldehyde 56248-10-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 1g
- Purity
- 98%min
- Supply Ability
- 100kgs/month
- Release date
- 2021-11-21