CX-3543

Product Name: CX-3543
CAS No.: 865311-47-3
Chemical Name: CX-3543
Synonyms: CX-3543;Quarfloxin;Quarfloxacin;Itarnafloxin;CX-3543/Quarfloxin;Quarfloxin (CX-3543);Quarfloxin, 10 mM in DMSO;CX 3543; QUARFLOXACIN; CX3543; CX-3543;inhibit,CX3543,Inhibitor,Quarfloxin,CX 3543,DNA/RNA Synthesis;2-(4-((R)-1-Methylpyrrolidin-2-yl)butanoyl)-6-(3-(pyrazin-2-yl)pyrrolidin-1-yl)-3H-benzo[b]pyrido[3,2,1-kl]phenoxazin-3-one
CBNumber: CB22526229
Molecular Formula: C35H33FN6O3
Formula Weight: 604.67
MOL File: 865311-47-3.mol

More

Less

CX-3543 Property

Boiling point:: 845.3±65.0 °C(Predicted)
Density: 1.44
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 11.46±0.20(Predicted)
form: Solid
color: Light yellow to yellow

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0005293
Product name: QUARFLOXIN
Purity: 95.00%
Packaging: 5MG
Price: $499.47
Updated: 2021/12/16

ChemScene

Product number: CS-0003553
Product name: Quarfloxin
Purity: 99.95%
Packaging: 10mg
Price: $600
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb612000
Product name: Quarfloxin (CX-3543)
Purity: >98%
Packaging: 10mg
Price: $912.9
Updated: 2021/12/16

ChemScene

Product number: CS-0003553
Product name: Quarfloxin
Purity: 99.95%
Packaging: 50mg
Price: $1000
Updated: 2021/12/16

ChemScene

Product number: CS-0003553
Product name: Quarfloxin
Purity: 99.95%
Packaging: 1mg
Price: $150
Updated: 2021/12/16

More

Less

CX-3543 Chemical Properties,Usage,Production

Uses

Quarfloxin (CX-3543), a fluoroquinolone derivative with antineoplastic activity, targets and inhibits RNA pol I activity, with IC50 values in the nanomolar range in neuroblastoma cells. Quarfloxin disrupts the interaction between the nucleolin protein and a G-quadruplex DNA structure in the ribosomal DNA (rDNA) template[1].

Definition

ChEBI: Itarnafloxin is a phenoxazine.

References

[1] Hald ?H, et al. Inhibitors of ribosome biogenesis repress the growth of MYCN-amplified neuroblastoma. Oncogene. 2018 Dec 12. DOI:10.1038/s41388-018-0611-7

CX-3543 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

CX-3543 Suppliers

China 29 United States 3 Global 32

shanghai cooperpharm co.,LTD .

Tel: +86-021-58975553
Fax: +86-021-58975554
Email: sales@cooperpharm.com
Country: China
ProdList: 1210
Advantage: 56

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3506
Advantage: 58

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4757
Advantage: 55

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28785
Advantage: 58

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30229
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 62220
Advantage: 58

InvivoChem

Tel: 13549236410
Email: sales@invivochem.cn
Country: China
ProdList: 6753
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Nantong QuanYi Biotechnology Co., Ltd

Tel: 0513-66337626 18051384581
Email: sales@chemhifuture.com
Country: China
ProdList: 5929
Advantage: 58

Suzhou Haiben Pharmaceutical Co., Ltd

Tel: 19353112242
Email: 1816280386@qq.com
Country: China
ProdList: 8045
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-85560043 15850508050
Fax: 025-85563444
Email: cindy.huang@synzest.com
Country: China
ProdList: 12000
Advantage: 58

Hubei wei shi reagent group ltd., company

Tel: 027-59101766 13125137661
Email: 2853877621@qq.com
Country: China
ProdList: 7977
Advantage: 58

RD International Technology Co., Limited

Tel: 18024082417
Email: market@ubiochem.com
Country: China
ProdList: 9835
Advantage: 58

Chengdu Peter-like Biotechnology Co., Ltd.

Tel: 028-81700200 13308200041
Email: 2851167782@qq.com
Country: China
ProdList: 11146
Advantage: 58

Sangon Biotech (Shanghai) Co.,Ltd.

Tel: 400-821-026
Email: Sales@sangon.com
Country: China
ProdList: 6710
Advantage: 58

Cayman Chemical Company

Tel: 800-364-9897
Email: sales@caymanchem.com
Country: China
ProdList: 6838
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

Adooq Bioscience LLC

Tel: 400-025-6535
Email: sales@adooq.cn
Country: China
ProdList: 6215
Advantage: 58

Selleck Chemicals

Tel: 400-668-6834
Email: info@selleck.cn
Country: China
ProdList: 6071
Advantage: 58

HANGZHOU LEAP CHEM CO., LTD.

Tel: +86-571-87711850
Email: market18@leapchem.com
Country: China
ProdList: 43339
Advantage: 58

Chongqing Aoyi Biotechnology Co., Ltd.

Tel: 13102311730,18585291730
Country: CHINA
ProdList: 140
Advantage: 58

Biorbyt Ltd.

Tel: --
Fax: --
Email: info@biorbyt.com
Country: CHINA
ProdList: 6482
Advantage: 58

Neobioscience Co., Ltd.

Tel: --
Fax: --
Email: info@neobioscience.com
Country: CHINA
ProdList: 6207
Advantage: 58

Absin Bioscience Inc.

Tel: --
Fax: --
Email: chenjw@absin.cn
Country: CHINA
ProdList: 6208
Advantage: 58

Proteintech China

Tel: --
Fax: --
Email: Proteintech-CN@ptglab.com
Country: CHINA
ProdList: 6290
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6650
Advantage: 58

Shanghai Biochempartner Co., Ltd.

Tel: --
Fax: --
Country: China
ProdList: 757
Advantage: 50

865311-47-3, CX-3543Related Search:

CX-3543

2-(4-((R)-1-Methylpyrrolidin-2-yl)butanoyl)-6-(3-(pyrazin-2-yl)pyrrolidin-1-yl)-3H-benzo[b]pyrido[3,2,1-kl]phenoxazin-3-one

5-Fluoro-N-[2-[(2S)-1-methyl-2-pyrrolidinyl]ethyl]-3-oxo-6-[3-(2-pyrazinyl)-1-pyrrolidinyl]-3H-benzo[b]pyrido[3,2,1-kl]phenoxazine-2-carboxamide

Itarnafloxin

Quarfloxacin

Quarfloxin (CX-3543)

Quarfloxin

CX 3543; QUARFLOXACIN; CX3543; CX-3543

3H-Benzo[b]pyrido[3,2,1-kl]phenoxazine-2-carboxamide, 5-fluoro-N-[2-[(2S)-1-methyl-2-pyrrolidinyl]ethyl]-3-oxo-6-[3-(2-pyrazinyl)-1-pyrrolidinyl]-

inhibit,CX3543,Inhibitor,Quarfloxin,CX 3543,DNA/RNA Synthesis

CX-3543/Quarfloxin

5-fluoro-N-(2-((S)-1-methylpyrrolidin-2-yl)ethyl)-3-oxo-6-(3-(pyrazin-2-yl)pyrrolidin-1-yl)-3H-benzo[b]pyrido[3,2,1-kl]phenoxazine-2-carboxamide

15-fluoro-N-{2-[(2S)-1-methylpyrrolidin-2-yl]ethyl}-18-oxo-14-[3-(pyrazin-2-yl)pyrrolidin-1-yl]-12-oxa-1-azapentacyclo[11.7.1.02,11.0?,?.01?,21]henicosa-2(11),3,5,7,9,13(21),14,16,19-nonaene-19-carboxamide

Quarfloxin, 10 mM in DMSO

865311-47-3

C35H33FN6O3