PFI-1

Product Name: PFI-1
CAS No.: 1403764-72-6
Chemical Name: PFI-1
Synonyms: PFI-1;CS-709;PFI-1cas;PF-6405761;PFI 1;PFI1;PF-06405761;PFI-1 USP/EP/BP;PFI-1 (PF-6405761);PFI-1 (PF-06405761);PFI-1;PFI-1;PFI 1;PFI1
CBNumber: CB22655765
Molecular Formula: C16H17N3O4S
Formula Weight: 347.39
MOL File: 1403764-72-6.mol

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PFI-1 Property

storage temp.: Sealed in dry,2-8°C
solubility: DMSO: ≥10mg/mL
form: powder
color: white to beige

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0352
Product name: PFI-1
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $122
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0352
Product name: PFI-1
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $393
Updated: 2024/03/01

Cayman Chemical

Product number: 11155
Product name: PFI-1
Purity: ≥98%
Packaging: 1mg
Price: $38
Updated: 2024/03/01

Cayman Chemical

Product number: 11155
Product name: PFI-1
Purity: ≥98%
Packaging: 5mg
Price: $104
Updated: 2024/03/01

Cayman Chemical

Product number: 11155
Product name: PFI-1
Purity: ≥98%
Packaging: 10mg
Price: $166
Updated: 2024/03/01

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PFI-1 Chemical Properties,Usage,Production

Description

PFI 1 is a BET bromodomain inhibitor that exhibits inhibitory activity at BRD2 and BRD4. PFI-1 is a selective BET bromodomain inhibitor with activity at BRD2 (IC50 = 98 nM) and BRD4 (IC50 = 220 nM). PFI 1 induces apoptosis and G1 cell cycle arrest in BET inhibitor-sensitive cell lines (MV4;11). PFI 1 also downregulates Aurora B expression in MV4;11 cells.

Uses

PFI-1 is used as a selective protein interaction inhibitor targetting BET bromodomains, used as regulators required for efficient expression of several growth promoting and anti-apoptotic genes.

Definition

ChEBI: 2-methoxy-N-(3-methyl-2-oxo-1,4-dihydroquinazolin-6-yl)benzenesulfonamide is a member of quinazolines.

storage

Store at RT

PFI-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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PFI-1 Suppliers

Canada 1 China 101 India 1 United Kingdom 2 United States 16 Global 121

Novachemistry

Tel: 44-20819178-90 02081917890
Fax: (0)2080432064
Email: info@novachemistry.com
Country: United Kingdom
ProdList: 4381
Advantage: 58

Tocris Bioscience

Tel: --
Fax: --
Email: customerservice@tocris.co.uk
Country: United Kingdom
ProdList: 5726
Advantage: 77

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View Lastest Price from PFI-1 manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: PFI-1 1403764-72-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-13

1403764-72-6, PFI-1Related Search:

I-BET151 (GSK1210151A) (+)-JQ1 BroMosporine RVX-208 OTX015 I-BET-762

PFI-1

PFI-1 (PF-6405761)

PFI-1 (PF-06405761)

PFI 1;PFI1

CS-709

PF-06405761

Benzenesulfonamide, 2-methoxy-N-(1,2,3,4-tetrahydro-3-methyl-2-oxo-6-quinazolinyl)-

2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide PFI-1 (PF-6405761)

2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydro-quinazolin-6-yl)-bezenesulfonamide

PFI-1;PFI-1;PFI 1;PFI1

PF-6405761

PFI-1 USP/EP/BP

PFI-1cas

PFI1 PFI-1 PF-06405761 PF06405761

Inhibitor,inhibit,Apoptosis,PFI-1,Autophagy,Epigenetic Reader Domain

1403764-72-6

Inhibitors

Inhibitor