ChemicalBook > CAS DataBase List > SB408124 Hydrochloride

SB408124 Hydrochloride

Product Name
SB408124 Hydrochloride
CAS No.
1431697-90-3
Chemical Name
SB408124 Hydrochloride
Synonyms
SB-408124 HCl;SB408124 Hydrochloride;SB 408124 Hydrochloride;SB-408124 (Hydrochloride);SB 408124 HYDROCHLORIDE;SB408124 HYDROCHLORIDE;N-(6,8-Difluoro-2-methyl-4-quinolinyl)-N'-[4-(dimethylamino)phenyl]urea hydrochloride (1:1)
CBNumber
CB22666684
Molecular Formula
C19H19ClF2N4O
Formula Weight
392.8301664
MOL File
1431697-90-3.mol
More
Less

SB408124 Hydrochloride Property

storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Powder
color 
White to gray
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

ChemScene
Product number
CS-1073
Product name
SB-408124(Hydrochloride)
Purity
98.09%
Packaging
5mg
Price
$72
Updated
2021/12/16
ApexBio Technology
Product number
A3798
Product name
SB-408124Hydrochloride
Packaging
5mg
Price
$87
Updated
2021/12/16
Biosynth Carbosynth
Product number
FS159311
Product name
SB 408124 hydrochloride
Packaging
10mg
Price
$125
Updated
2021/12/16
ApexBio Technology
Product number
A3798
Product name
SB-408124Hydrochloride
Packaging
10mg
Price
$142
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611826
Product name
SB-408124 hydrochloride
Packaging
10mg
Price
$210.8
Updated
2021/12/16
More
Less

SB408124 Hydrochloride Chemical Properties,Usage,Production

Uses

SB 408124 Hydrochloride is a salt form of SB 40812 (S155088), which 4 is a novel OX-1 antagonist.

in vivo

SB-408124 reduces anxiety after psychotraumatic exposure. Predator induces acute psychotraumatic exposure decrease corticoliberin level in the rat's amygdala. Intranasal administration of SB-408124 restores it closely to normal and has an anxiolytic effect on animal behaviour[2].
Bilateral paraventricular nucleus microinjection of SB-408124 (30 pmol/50 nL per side) results in a greater reduction in mean arterial pressure (MAP) in high-salt intake (-16?mmHg) compared with NS-fed (-4?mmHg) anesthetized Dahl salt-sensitive rats[3].

IC 50

OX1 Receptor: 57 nM (Ki, in whole cell ); OX1 Receptor: 27 nM (Ki, in cell membrane)

SB408124 Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

SB408124 Hydrochloride Suppliers

China 29 United States 6 Global 35
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
SPIRO PHARMA
Tel
Fax
-
Email
eric_feng1954@126.com
Country
China
ProdList
9248
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Guangzhou QiYun Biotechnology Co., Ltd.
Tel
020-61288194 61288195
Fax
020-61288700
Email
505721671@qq.com
Country
China
ProdList
3866
Advantage
58
Shanghai SuperLan Chemcial Technique Centre
Tel
0-2022843681 15618226720
Fax
+86-21-51601218
Email
chaolaichem@foxmail.com
Country
China
ProdList
12476
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Angel Pharmatech, Ltd.
Tel
17317130613
Fax
QQ3358272972
Email
3358272972@qq.com
Country
China
ProdList
3276
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Absin Bioscience Inc.
Tel
021-38015121 18438616290
Email
lanwu@univ-bio.com
Country
China
ProdList
24731
Advantage
58
Shanghai hongqu biomedical technology co. LTD
Tel
88888888888
Email
hongquchem@qq.com
Country
China
ProdList
5132
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
Advantage
58
InvivoChem
Tel
13549236410
Email
sales@invivochem.cn
Country
China
ProdList
6753
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
021-50706066 15221275939
Email
shenlinxing@macklin.cn
Country
China
ProdList
14580
Advantage
58
Biosynth Biological Technology (Suzhou) Co Ltd
Tel
51288865780
Email
sales@biosynth.com
Country
China
ProdList
6051
Advantage
58
Adooq Bioscience LLC
Tel
400-025-6535
Email
sales@adooq.cn
Country
China
ProdList
6215
Advantage
58
ATK CHEMICAL COMPANY LIMITED
Tel
+undefined-21-51877795
Fax
+86 21 5161 9052/ 5187 7796
Email
ivan@atkchemical.com
Country
China
ProdList
33024
Advantage
60
Hangzhou MolCore BioPharmatech Co.,Ltd.
Tel
+86-057181025280; +8617767106207
Fax
0571-85806285
Email
sales@molcore.com
Country
China
ProdList
49734
Advantage
58
Guangzhou Tuoshan Biotechnology Co., Ltd.
Tel
19928332050
Country
CHINA
ProdList
161
Advantage
58
Guangzhou Baben Biotechnology Co., Ltd.
Tel
17130848100
Country
CHINA
ProdList
143
Advantage
58
Guangzhou Junuo Biotechnology Co., Ltd.
Tel
13432975901
Country
CHINA
ProdList
132
Advantage
58
Guangzhou Ruifeng Biotechnology Co., Ltd.
Tel
14715141318
Country
CHINA
ProdList
181
Advantage
58
Shanghai Shitang Industrial Co., Ltd.
Tel
17301778918
Country
CHINA
ProdList
105
Advantage
58
Guangzhou Weike Biotechnology Co., Ltd.
Tel
15902098758
Country
CHINA
ProdList
133
Advantage
58
Guangzhou Yiran Biotechnology Co., Ltd.
Tel
15571990006
Country
CHINA
ProdList
141
Advantage
58
Biorbyt Ltd.
Tel
--
Fax
--
Email
info@biorbyt.com
Country
CHINA
ProdList
6482
Advantage
58
Absin Bioscience Inc.
Tel
--
Fax
--
Email
chenjw@absin.cn
Country
CHINA
ProdList
6208
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6650
Advantage
58
Shanghai Weiwei Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
sales@wheybio.com
Country
CHINA
ProdList
4398
Advantage
58

1431697-90-3, SB408124 HydrochlorideRelated Search:


  • SB 408124 Hydrochloride
  • SB-408124 (Hydrochloride)
  • SB408124 Hydrochloride
  • N-(6,8-Difluoro-2-methyl-4-quinolinyl)-N'-[4-(dimethylamino)phenyl]urea hydrochloride (1:1)
  • SB-408124 HCl
  • SB 408124 HYDROCHLORIDE;SB408124 HYDROCHLORIDE
  • 1431697-90-3
  • C19H18F2N4OHCl