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SB408124 Hydrochloride

Product Name
SB408124 Hydrochloride
CAS No.
1431697-90-3
Chemical Name
SB408124 Hydrochloride
Synonyms
SB-408124 HCl;SB408124 Hydrochloride;SB 408124 Hydrochloride;SB-408124 (Hydrochloride);SB 408124 HYDROCHLORIDE;SB408124 HYDROCHLORIDE;N-(6,8-Difluoro-2-methyl-4-quinolinyl)-N'-[4-(dimethylamino)phenyl]urea hydrochloride (1:1)
CBNumber
CB22666684
Molecular Formula
C19H19ClF2N4O
Formula Weight
392.8301664
MOL File
1431697-90-3.mol
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SB408124 Hydrochloride Property

storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Powder
color 
White to gray
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-1073
Product name
SB-408124(Hydrochloride)
Purity
98.09%
Packaging
5mg
Price
$72
Updated
2021/12/16
ApexBio Technology
Product number
A3798
Product name
SB-408124Hydrochloride
Packaging
5mg
Price
$87
Updated
2021/12/16
Biosynth Carbosynth
Product number
FS159311
Product name
SB 408124 hydrochloride
Packaging
10mg
Price
$125
Updated
2021/12/16
ApexBio Technology
Product number
A3798
Product name
SB-408124Hydrochloride
Packaging
10mg
Price
$142
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611826
Product name
SB-408124 hydrochloride
Packaging
10mg
Price
$210.8
Updated
2021/12/16
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SB408124 Hydrochloride Chemical Properties,Usage,Production

Uses

SB 408124 Hydrochloride is a salt form of SB 40812 (S155088), which 4 is a novel OX-1 antagonist.

in vivo

SB-408124 reduces anxiety after psychotraumatic exposure. Predator induces acute psychotraumatic exposure decrease corticoliberin level in the rat's amygdala. Intranasal administration of SB-408124 restores it closely to normal and has an anxiolytic effect on animal behaviour[2].
Bilateral paraventricular nucleus microinjection of SB-408124 (30 pmol/50 nL per side) results in a greater reduction in mean arterial pressure (MAP) in high-salt intake (-16?mmHg) compared with NS-fed (-4?mmHg) anesthetized Dahl salt-sensitive rats[3].

IC 50

OX1 Receptor: 57 nM (Ki, in whole cell ); OX1 Receptor: 27 nM (Ki, in cell membrane)

SB408124 Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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SB408124 Hydrochloride Suppliers

China 29 United States 6 Global 35
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4660
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354;
Email
support@targetmol.com
Country
United States
ProdList
39035
Advantage
58
ApexBio Technology
Tel
--
Fax
--
Email
sales@apexbt.com
Country
United States
ProdList
6251
Advantage
58

1431697-90-3, SB408124 HydrochlorideRelated Search:


  • SB 408124 Hydrochloride
  • SB-408124 (Hydrochloride)
  • SB408124 Hydrochloride
  • N-(6,8-Difluoro-2-methyl-4-quinolinyl)-N'-[4-(dimethylamino)phenyl]urea hydrochloride (1:1)
  • SB-408124 HCl
  • SB 408124 HYDROCHLORIDE;SB408124 HYDROCHLORIDE
  • 1431697-90-3
  • C19H18F2N4OHCl