Bosutinib-d8

Product Name: Bosutinib-d8
CAS No.: 2733145-45-2
Chemical Name: Bosutinib-d8
Synonyms: D8-Bosutinib;Bosutinib-d8;4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methylpiperazin-1-yl-2,2,3,3,5,5,6,6-d8)propoxy)quinoline-3-carbonitrile;4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-{3-[4-methyl(2,2,3,3,5,5,6,6-2H?)piperazin-1-yl]propoxy}quinoline-3-carbonitrile
CBNumber: CB22673646
Molecular Formula: C26H29Cl2N5O3
Formula Weight: 530.44616
MOL File: 2733145-45-2.mol

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Bosutinib-d8 Property

solubility: DMSO: Slightly Soluble
Methanol: Slightly Soluble
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 25460
Product name: Bosutinib-d8
Purity: ≥99% deuterated forms (d1-d8)
Packaging: 500μg
Price: $145
Updated: 2024/03/01

Cayman Chemical

Product number: 25460
Product name: Bosutinib-d8
Purity: ≥99% deuterated forms (d1-d8)
Packaging: 1mg
Price: $276
Updated: 2024/03/01

Usbiological

Product number: 162936
Product name: Bosutinib-d8
Packaging: 1mg
Price: $460
Updated: 2021/12/16

ChemScene

Product number: CS-0111328
Product name: BosutinibD8
Purity: ≥99.0%
Packaging: 1mg
Price: $225
Updated: 2021/12/16

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Bosutinib-d8 Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

A novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells. This is the labeled analog.

References

[1] DIANE H. BOSCHELLI. Optimization of 4-Phenylamino-3-quinolinecarbonitriles as Potent Inhibitors of Src Kinase Activity[J]. Journal of Medicinal Chemistry, 2001, 44 23: 3965-3977. DOI: 10.1021/jm0102250
[2] JENNIFER M GOLAS. SKI-606, a 4-anilino-3-quinolinecarbonitrile dual inhibitor of Src and Abl kinases, is a potent antiproliferative agent against chronic myelogenous leukemia cells in culture and causes regression of K562 xenografts in nude mice.[J]. Cancer research, 2003, 63 2: 375-381.
[3] L L REMSING RIX. Global target profile of the kinase inhibitor bosutinib in primary chronic myeloid leukemia cells[J]. Leukemia, 2008, 23 3: 477-485. DOI: 10.1038/leu.2008.334

Bosutinib-d8 Preparation Products And Raw materials

Raw materials

Preparation Products

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Bosutinib-d8 Suppliers

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2733145-45-2, Bosutinib-d8Related Search:

Sunitinib Cabozantinib

Bosutinib-d8

4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methylpiperazin-1-yl-2,2,3,3,5,5,6,6-d8)propoxy)quinoline-3-carbonitrile

4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-{3-[4-methyl(2,2,3,3,5,5,6,6-2H?)piperazin-1-yl]propoxy}quinoline-3-carbonitrile

D8-Bosutinib

2733145-45-2