Bosutinib-d8
- Product Name
- Bosutinib-d8
- CAS No.
- 2733145-45-2
- Chemical Name
- Bosutinib-d8
- Synonyms
- D8-Bosutinib;Bosutinib-d8;4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methylpiperazin-1-yl-2,2,3,3,5,5,6,6-d8)propoxy)quinoline-3-carbonitrile;4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-{3-[4-methyl(2,2,3,3,5,5,6,6-2H?)piperazin-1-yl]propoxy}quinoline-3-carbonitrile
- CBNumber
- CB22673646
- Molecular Formula
- C26H29Cl2N5O3
- Formula Weight
- 530.44616
- MOL File
- 2733145-45-2.mol
Bosutinib-d8 Property
- solubility
- DMSO: Slightly Soluble
Methanol: Slightly Soluble - form
- Solid
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- 25460
- Product name
- Bosutinib-d8
- Purity
- ≥99% deuterated forms (d1-d8)
- Packaging
- 500μg
- Price
- $145
- Updated
- 2024/03/01
- Product number
- 25460
- Product name
- Bosutinib-d8
- Purity
- ≥99% deuterated forms (d1-d8)
- Packaging
- 1mg
- Price
- $276
- Updated
- 2024/03/01
- Product number
- 162936
- Product name
- Bosutinib-d8
- Packaging
- 1mg
- Price
- $460
- Updated
- 2021/12/16
- Product number
- CS-0111328
- Product name
- BosutinibD8
- Purity
- ≥99.0%
- Packaging
- 1mg
- Price
- $225
- Updated
- 2021/12/16
Bosutinib-d8 Chemical Properties,Usage,Production
Chemical Properties
Pale Yellow Solid
Uses
A novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells. This is the labeled analog.
References
[1] DIANE H. BOSCHELLI. Optimization of 4-Phenylamino-3-quinolinecarbonitriles as Potent Inhibitors of Src Kinase Activity[J]. Journal of Medicinal Chemistry, 2001, 44 23: 3965-3977. DOI: 10.1021/jm0102250
[2] JENNIFER M GOLAS. SKI-606, a 4-anilino-3-quinolinecarbonitrile dual inhibitor of Src and Abl kinases, is a potent antiproliferative agent against chronic myelogenous leukemia cells in culture and causes regression of K562 xenografts in nude mice.[J]. Cancer research, 2003, 63 2: 375-381.
[3] L L REMSING RIX. Global target profile of the kinase inhibitor bosutinib in primary chronic myeloid leukemia cells[J]. Leukemia, 2008, 23 3: 477-485. DOI: 10.1038/leu.2008.334
Bosutinib-d8 Preparation Products And Raw materials
Raw materials
Preparation Products
Bosutinib-d8 Suppliers
- Tel
- --
- Fax
- --
- info@trc-canada.com
- Country
- Canada
- ProdList
- 6038
- Advantage
- 71