ChemicalBook > CAS DataBase List > NSC-703786
NSC-703786
- Product Name
- NSC-703786
- CAS No.
- 260443-89-8
- Chemical Name
- NSC-703786
- Synonyms
- 5F203;5F-203;NSC-703786;5-fluoro 203;5F 203 (5F-203;NSC-703786 (5F-203);5-fluoro 203, 10 mM in DMSO;4-(5-Fluorobenzo[d]thiazol-2-yl)-2-methylaniline;4-(5-Fluorobenzothiazol-2-yl)-2-methylphenylamine;4-(5-fluoro-1,3-benzothiazol-2-yl)-2-methylaniline
- CBNumber
- CB22751089
- Molecular Formula
- C14H11FN2S
- Formula Weight
- 258.31
- MOL File
- 260443-89-8.mol
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NSC-703786 Property
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble20mg/mL, clear
- form
- powder
- color
- white to beige
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML0983
- Product name
- 5F-203
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $72.5
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- SML0983
- Product name
- 5F-203
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $466
- Updated
- 2023/01/07
Cayman Chemical
- Product number
- 17677
- Product name
- 5-fluoro 203
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 17677
- Product name
- 5-fluoro 203
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $93
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 17677
- Product name
- 5-fluoro 203
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $169
- Updated
- 2024/03/01
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NSC-703786 Chemical Properties,Usage,Production
Uses
5-Fluoro 203 is a cytotoxic agent which actiates AhR signaling, inducing transcription of CYP1A1 which leads to the formation of DNA adducts and cell cycle arrest.
Biological Activity
5F-203 is a cytotoxic molecule th at forms DNA adducts th at lead to cell death. 5F-203 induces aryl hydrocarbon receptor signaling, and elevates expression of CYP1A1. Treatment of cells with 5F-203 also leads to elevation of reactive oxygen species and activation of p38, JNK and ERK.
NSC-703786 Preparation Products And Raw materials
Raw materials
Preparation Products
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