TCS HDAC6 20b

Product Name: TCS HDAC6 20b
CAS No.: 956154-63-5
Chemical Name: TCS HDAC6 20b
Synonyms: TCS HDAC6 20b;DQZMLPMCOMRJOR-MOVGKWKRSA-N;S-[(6S)-7-(1-adamantylamino)-6-[(2-methylpropan-2-yl)oxycarbonylamino]-7-oxoheptyl] 2-methylpropanethioate;2-Methylpropanethioic acid-S-[(6S)-6-[[(1,1-dimethylethoxy)carbonyl]amino]-7-oxo-7-(tricyclo[3.3.1.13,7]dec-1-ylamino)heptyl] ester;Propanethioic acid, 2-methyl-, S-[(6S)-6-[[(1,1-dimethylethoxy)carbonyl]amino]-7-oxo-7-(tricyclo[3.3.1.13,7]dec-1-ylamino)heptyl] ester
CBNumber: CB23037557
Molecular Formula: C26H44N2O4S
Formula Weight: 480.7
MOL File: 956154-63-5.mol

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TCS HDAC6 20b Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: White Oily foam

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 14977
Product name: TCS HDAC6 20b
Purity: ≥95%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 14977
Product name: TCS HDAC6 20b
Purity: ≥95%
Packaging: 5mg
Price: $145
Updated: 2024/03/01

Tocris

Product number: 4805
Product name: TCSHDAC620b
Purity: ≥98%(HPLC)
Packaging: 10
Price: $224
Updated: 2021/12/16

Usbiological

Product number: 256885
Product name: TCS HDAC6 20b
Packaging: 10mg
Price: $480
Updated: 2021/12/16

TRC

Product number: T012700
Product name: TCSHDAC620b
Packaging: 25mg
Price: $1260
Updated: 2021/12/16

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TCS HDAC6 20b Chemical Properties,Usage,Production

Description

TCS HDAC6 20b is an inhibitor of histone deacetylase 6 (HDAC6) that inhibits the growth of HCT116 cells synergistically when used at a concentration of 5 μM in combination with paclitaxel , but it has no activity on cell growth in HCT116 cells when used alone. It inhibits cell growth of α-positive MCF-7 breast cancer cells treated with estrogen but not untreated cells.

Uses

TCS HDAC6 20b is a histone deacetylase 6 (HDAC6)-selective inhibitor.

References

[1]. suzuki t, kouketsu a, itoh y, et al. highly potent and selective histone deacetylase 6 inhibitors designed based on a small-molecular substrate. j med chem, 2006, 49(16): 4809-4812.
[2]. itoh y, suzuki t, kouketsu a, et al. design, synthesis, structure--selectivity relationship, and effect on human cancer cells of a novel series of histone deacetylase 6-selective inhibitors. j med chem, 2007, 50(22): 5425-5438.

TCS HDAC6 20b Preparation Products And Raw materials

Raw materials

Preparation Products

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TCS HDAC6 20b Suppliers

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956154-63-5, TCS HDAC6 20bRelated Search:

TCS HDAC6 20b

DQZMLPMCOMRJOR-MOVGKWKRSA-N

S-[(6S)-7-(1-adamantylamino)-6-[(2-methylpropan-2-yl)oxycarbonylamino]-7-oxoheptyl] 2-methylpropanethioate

2-Methylpropanethioic acid-S-[(6S)-6-[[(1,1-dimethylethoxy)carbonyl]amino]-7-oxo-7-(tricyclo[3.3.1.13,7]dec-1-ylamino)heptyl] ester

Propanethioic acid, 2-methyl-, S-[(6S)-6-[[(1,1-dimethylethoxy)carbonyl]amino]-7-oxo-7-(tricyclo[3.3.1.13,7]dec-1-ylamino)heptyl] ester

956154-63-5

C26H44N2O4S