Mutant IDH1-IN-2

Product Name: Mutant IDH1-IN-2
CAS No.: 1429176-69-1
Chemical Name: Mutant IDH1-IN-2
Synonyms: Mutant IDH1-IN-2;Mutant IDH1 inhibitor 2;AG-881,Mutant IDH1-IN-2;Mutant IDH1-IN-2, 10 mM in DMSO;inhibit,Mutant IDH1 IN 2,Inhibitor,Mutant IDH-1-IN-2,Mutant IDH1IN2,Isocitrate Dehydrogenase (IDH);(S)-3-(2-(((S)-1-(4-((4,4-Difluoropiperidin-1-yl)methyl)phenyl)ethyl)amino)pyrimidin-4-yl)-4-isopropyloxazolidin-2-one;2-Oxazolidinone, 3-[2-[[(1S)-1-[4-[(4,4-difluoro-1-piperidinyl)methyl]phenyl]ethyl]amino]-4-pyrimidinyl]-4-(1-methylethyl)-, (4S)-
CBNumber: CB23048663
Molecular Formula: C24H31F2N5O2
Formula Weight: 459.53
MOL File: 1429176-69-1.mol

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Mutant IDH1-IN-2 Property

Boiling point:: 578.1±60.0 °C(Predicted)
Density: 1.27±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 50 mg/mL (108.81 mM);Water : < 0.1 mg/mL (insoluble)
pka: 5.07±0.10(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-5119
Product name: MutantIDH1-IN-2
Purity: >98.0%
Packaging: 5mg
Price: $300
Updated: 2021/12/16

ChemScene

Product number: CS-5119
Product name: MutantIDH1-IN-2
Purity: >98.0%
Packaging: 10mg
Price: $500
Updated: 2021/12/16

ChemScene

Product number: CS-5119
Product name: MutantIDH1-IN-2
Purity: >98.0%
Packaging: 25mg
Price: $950
Updated: 2021/12/16

ChemScene

Product number: CS-5119
Product name: MutantIDH1-IN-2
Purity: >98.0%
Packaging: 50mg
Price: $1550
Updated: 2021/12/16

Crysdot

Product number: CD31003522
Product name: MutantIDH1-IN-2
Purity: 98+%
Packaging: 5mg
Price: $243
Updated: 2021/12/16

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Mutant IDH1-IN-2 Chemical Properties,Usage,Production

Uses

Mutant IDH1-IN-2 is a inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with IC50 of in LS-MS biochemical assay, IC50 of 16.6 nM in Fluorescence biochemical assay. Target: Mutant IDH1 Mutant IDH1-IN-2 has a neomorphic activity and in the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell-proliferation disorders, such as cancer. More bioactivity information in Patent WO 2013046136A1 (Example 224).

IC 50

IDH1

References

[1] Huangshu, et al. 3-Pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH and their preparation

Mutant IDH1-IN-2 Preparation Products And Raw materials

Raw materials

Preparation Products

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Mutant IDH1-IN-2 Suppliers

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1429176-69-1, Mutant IDH1-IN-2Related Search:

Mutant IDH1-IN-2

AG-881,Mutant IDH1-IN-2

Mutant IDH1 inhibitor 2

2-Oxazolidinone, 3-[2-[[(1S)-1-[4-[(4,4-difluoro-1-piperidinyl)methyl]phenyl]ethyl]amino]-4-pyrimidinyl]-4-(1-methylethyl)-, (4S)-

inhibit,Mutant IDH1 IN 2,Inhibitor,Mutant IDH-1-IN-2,Mutant IDH1IN2,Isocitrate Dehydrogenase (IDH)

Mutant IDH1-IN-2, 10 mM in DMSO

(S)-3-(2-(((S)-1-(4-((4,4-Difluoropiperidin-1-yl)methyl)phenyl)ethyl)amino)pyrimidin-4-yl)-4-isopropyloxazolidin-2-one

1429176-69-1

C24H31F2N5O2