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Nudol

Product Name: Nudol
CAS No.: 86630-46-8
Chemical Name: Nudol
Synonyms: Nudol;3,4-Dimethoxy-2,7-phenanthrenediol;2,7-dihydroxy-3,4-dimethoxyphenanthrene;Nudol/2,7-dihydroxy-3,4-dimethoxyphenanthrene
CBNumber: CB23051450
Molecular Formula: C16H14O4
Formula Weight: 270.27996
MOL File: 86630-46-8.mol

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Hazard and Precautionary Statements (GHS)

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Nudol Chemical Properties,Usage,Production

Uses

Nudol is a phenanthrene compound that has anti-cancer activity. Nudol inhibits cell proliferation, induces cell apoptosis. Nudol inhibits MMP-2M and MMP-9 activity (Ki: 988.9 nM, 1.76 μM, respectively). Nudol can be used in the research of cancers, such as osteosarcoma[1][2].

IC 50

MMP-2: 988.9 nM (Ki); MMP-9: 1.76 μM (Ki)

References

[1] Yuying Zhang, et al. Nudol, a phenanthrene derivative from Dendrobium nobile, induces cell cycle arrest and apoptosis and inhibits migration in osteosarcoma cells. Drug Des Devel Ther. 2019 Jul 29;13:2591-2601. DOI:10.2147/DDDT.S180610
[2] Mohammad Al-Amin, et al. Inhibitory Effect of Dioscorea bulbifera Tubers on the Migration of Triple-Negative Breast Cancer Cells. Breast Cancer Cells. Rev. Bras. Farmacogn. 31, 335–341 (2021).

Nudol Preparation Products And Raw materials

Raw materials

Preparation Products

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86630-46-8, NudolRelated Search:

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Nudol

3,4-Dimethoxy-2,7-phenanthrenediol

2,7-dihydroxy-3,4-dimethoxyphenanthrene

Nudol/2,7-dihydroxy-3,4-dimethoxyphenanthrene

86630-46-8