Nudol
- Product Name
- Nudol
- CAS No.
- 86630-46-8
- Chemical Name
- Nudol
- Synonyms
- Nudol;3,4-Dimethoxy-2,7-phenanthrenediol;2,7-dihydroxy-3,4-dimethoxyphenanthrene;Nudol/2,7-dihydroxy-3,4-dimethoxyphenanthrene
- CBNumber
- CB23051450
- Molecular Formula
- C16H14O4
- Formula Weight
- 270.27996
- MOL File
- 86630-46-8.mol
Nudol Chemical Properties,Usage,Production
Uses
Nudol is a phenanthrene compound that has anti-cancer activity. Nudol inhibits cell proliferation, induces cell apoptosis. Nudol inhibits MMP-2M and MMP-9 activity (Ki: 988.9 nM, 1.76 μM, respectively). Nudol can be used in the research of cancers, such as osteosarcoma[1][2].
IC 50
MMP-2: 988.9 nM (Ki); MMP-9: 1.76 μM (Ki)
References
[1] Yuying Zhang, et al. Nudol, a phenanthrene derivative from Dendrobium nobile, induces cell cycle arrest and apoptosis and inhibits migration in osteosarcoma cells. Drug Des Devel Ther. 2019 Jul 29;13:2591-2601. DOI:10.2147/DDDT.S180610
[2] Mohammad Al-Amin, et al. Inhibitory Effect of Dioscorea bulbifera Tubers on the Migration of Triple-Negative Breast Cancer Cells. Breast Cancer Cells. Rev. Bras. Farmacogn. 31, 335–341 (2021).
Nudol Preparation Products And Raw materials
Raw materials
Preparation Products
Nudol Suppliers
- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 52923
- Advantage
- 58
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- +1-781-999-5354;
- support@targetmol.com
- Country
- United States
- ProdList
- 39035
- Advantage
- 58