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MitoB

Product Name
MitoB
CAS No.
1247025-84-8
Chemical Name
MitoB
Synonyms
MitoB;MitoB (bromide);MitoB >=98% (HPLC);3-(Dihydroxyboronyl)benzyltriphenylphosphonium bromide;(3-boronophenyl)methyl]triphenyl-phosphonium,monobromide
CBNumber
CB23152678
Molecular Formula
C25H23BBrO2P
Formula Weight
477.137681
MOL File
1247025-84-8.mol
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MitoB Property

storage temp. 
Store at -20°C
solubility 
DMF: 5 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 0.5 mg/ml
form 
A crystalline solid
color 
white to beige
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1300
Product name
MitoB
Purity
≥98% (HPLC)
Packaging
5 mg
Price
$100.7
Updated
2025/07/31
Sigma-Aldrich
Product number
SML1300
Product name
MitoB
Purity
≥98% (HPLC)
Packaging
25 mg
Price
$414
Updated
2025/07/31
Cayman Chemical
Product number
17116
Product name
MitoB
Purity
≥95%
Packaging
5mg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
17116
Product name
MitoB
Purity
≥95%
Packaging
10mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
17116
Product name
MitoB
Purity
≥95%
Packaging
50mg
Price
$535
Updated
2024/03/01
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MitoB Chemical Properties,Usage,Production

Description

MitoB is a ratiometric mass spectrometry probe that can be used for assessing changes in H2O2 within mitochondria in vivo. MitoB contains a triphenylphosphonium cation component that drives its accumulation in mitochondria where its arylboronic moiety selectively reacts with H2O2 to produce a phenol product, MitoP. Quantifying the MitoP/MitoB ratio by LC-MS/MS reflects the mitochondrial matrix H2O2 concentration.

Uses

MitoB is used as a probe in assessing the changes in hydrogen peroxide within mitochondria in vivo.

References

[1] HELENA M COCHEMé. Using the mitochondria-targeted ratiometric mass spectrometry probe MitoB to measure H2O2 in living Drosophila[J]. Nature Protocols, 2012, 7 5: 946-958. DOI: 10.1038/nprot.2012.035
[2] HELENA M COCHEMé. Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix.[J]. Cell metabolism, 2011, 13 3: 340-350. DOI: 10.1016/j.cmet.2011.02.003

MitoB Preparation Products And Raw materials

Raw materials

Preparation Products

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MitoB Suppliers

China 27 United States 3 Global 30
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 13675144456
Fax
025-85563444
Email
sean.lv@synzest.com
Country
China
ProdList
11438
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
Advantage
58
Shanghai klamar Reagent Co., LTD
Tel
4001650900 13817534909
Email
3003940895@qq.com
Country
China
ProdList
10714
Advantage
58
Shanghai Yiyan Biotechnology Co. , Ltd.
Tel
021-69985186 13611928337
Email
3427709316@qq.com
Country
China
ProdList
7982
Advantage
58
Shanghai Haohong Scientific Co., Ltd.
Tel
400-8210725 4008210725
Email
malulu@leyan.com
Country
China
ProdList
40000
Advantage
58
Cayman Chemical Company
Tel
800-364-9897
Email
sales@caymanchem.com
Country
China
ProdList
6838
Advantage
58

1247025-84-8, MitoBRelated Search:


  • MitoB
  • (3-boronophenyl)methyl]triphenyl-phosphonium,monobromide
  • MitoB >=98% (HPLC)
  • 3-(Dihydroxyboronyl)benzyltriphenylphosphonium bromide
  • MitoB (bromide)
  • 1247025-84-8