MitoB
- Product Name
- MitoB
- CAS No.
- 1247025-84-8
- Chemical Name
- MitoB
- Synonyms
- MitoB;MitoB (bromide);MitoB >=98% (HPLC);3-(Dihydroxyboronyl)benzyltriphenylphosphonium bromide;(3-boronophenyl)methyl]triphenyl-phosphonium,monobromide
- CBNumber
- CB23152678
- Molecular Formula
- C25H23BBrO2P
- Formula Weight
- 477.137681
- MOL File
- 1247025-84-8.mol
MitoB Property
- storage temp.
- Store at -20°C
- solubility
- DMF: 5 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 0.5 mg/ml
- form
- A crystalline solid
- color
- white to beige
N-Bromosuccinimide Price
- Product number
- SML1300
- Product name
- MitoB
- Purity
- ≥98% (HPLC)
- Packaging
- 5 mg
- Price
- $100.7
- Updated
- 2025/07/31
- Product number
- SML1300
- Product name
- MitoB
- Purity
- ≥98% (HPLC)
- Packaging
- 25 mg
- Price
- $414
- Updated
- 2025/07/31
- Product number
- 17116
- Product name
- MitoB
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $68
- Updated
- 2024/03/01
- Product number
- 17116
- Product name
- MitoB
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $121
- Updated
- 2024/03/01
- Product number
- 17116
- Product name
- MitoB
- Purity
- ≥95%
- Packaging
- 50mg
- Price
- $535
- Updated
- 2024/03/01
MitoB Chemical Properties,Usage,Production
Description
MitoB is a ratiometric mass spectrometry probe that can be used for assessing changes in H2O2 within mitochondria in vivo. MitoB contains a triphenylphosphonium cation component that drives its accumulation in mitochondria where its arylboronic moiety selectively reacts with H2O2 to produce a phenol product, MitoP. Quantifying the MitoP/MitoB ratio by LC-MS/MS reflects the mitochondrial matrix H2O2 concentration.
Uses
MitoB is used as a probe in assessing the changes in hydrogen peroxide within mitochondria in vivo.
References
[1] HELENA M COCHEMé. Using the mitochondria-targeted ratiometric mass spectrometry probe MitoB to measure H2O2 in living Drosophila[J]. Nature Protocols, 2012, 7 5: 946-958. DOI: 10.1038/nprot.2012.035
[2] HELENA M COCHEMé. Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix.[J]. Cell metabolism, 2011, 13 3: 340-350. DOI: 10.1016/j.cmet.2011.02.003
MitoB Preparation Products And Raw materials
Raw materials
Preparation Products
MitoB Suppliers
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- +1-781-999-5354;
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- Country
- United States
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