Prodipine (hydrochloride)
- Product Name
- Prodipine (hydrochloride)
- CAS No.
- 31314-39-3
- Chemical Name
- Prodipine (hydrochloride)
- Synonyms
- Prodipine (hydrochloride)
- CBNumber
- CB23175574
- Molecular Formula
- C20H26ClN
- Formula Weight
- 315.89
- MOL File
- 31314-39-3.mol
Prodipine (hydrochloride) Property
- Melting point:
- 267°
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- color
- Off-white to yellow
Safety
- HS Code
- 2933399990
N-Bromosuccinimide Price
- Product number
- CS-6539
- Product name
- Prodipinehydrochloride
- Purity
- 99.50%
- Packaging
- 1mg
- Price
- $104
- Updated
- 2021/12/16
- Product number
- 5246AH
- Product name
- 3,3-Diphenylpiperidinehydrochloride
- Packaging
- 100mg
- Price
- $287
- Updated
- 2021/12/16
- Product number
- CHM0002092
- Product name
- 3,3-DIPHENYL PIPERIDINE HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $721.59
- Updated
- 2021/12/16
- Product number
- CHM0002092
- Product name
- 3,3-DIPHENYL PIPERIDINE HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1309.77
- Updated
- 2021/12/16
- Product number
- CHM0002092
- Product name
- 3,3-DIPHENYL PIPERIDINE HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $3565.49
- Updated
- 2021/12/16
Prodipine (hydrochloride) Chemical Properties,Usage,Production
Biological Activity
Prodipine (hydrochloride) is a diphenylphosphonate derivative. Inhibits dipeptidyl peptidase IV (DPP IV) in purified rabbit and plasma with IC50 of 4.5 μM and 30 μM, respectively.
in vitro
Prodipine (hydrochloride), a diphenyl-phosphonate derivative selected from a group of slow-binding irreversible inhibitors of this enzyme. The IC 50 values of Prodipine for purified and plasma DPP IV from the rabbit are 4.5 μM and 30 μM, respectively.
in vivo
Male rabbits weighing 3-4 kg receive a single intravenous injection with 10 mg Prodipine (hydrochloride) or saline. After 1 hr, plasma DPP IV activity has decreased to less than 20% of the preinjection value and remains unchanged during a 24 hr observation period. A profound and long-lasting inhibition of plasma DPP IV activity is observed in the treated animals (1, 5 or 10 mg). It takes 5 to 8 days to reach half of the pretreatment DPP IV activity and generally more than 20 days for a complete recovery.
target
IC50: 4.5 μM (purified DPP IV), 30 μM (plasma DPP IV)
Prodipine (hydrochloride) Preparation Products And Raw materials
Raw materials
Preparation Products
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