ChemicalBook > CAS DataBase List > DBCO-PEG4-NH-Boc

DBCO-PEG4-NH-Boc

Product Name
DBCO-PEG4-NH-Boc
CAS No.
1255942-12-1
Chemical Name
DBCO-PEG4-NH-Boc
Synonyms
DBCO-PEG4-NH-Boc;DBCO-NHCO-PEG4-NH-Boc;DBCO-NHCO-PEG4-t-Boc Amine;5,8,11,14-Tetraoxa-2,18-diazaheneicosanoic acid, 21-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-17,21-dioxo-, 1,1-dimethylethyl ester
CBNumber
CB23373604
Molecular Formula
C34H45N3O8
Formula Weight
623.74
MOL File
1255942-12-1.mol
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DBCO-PEG4-NH-Boc Property

Boiling point:
840.5±65.0 °C(Predicted)
Density 
1.21±0.1 g/cm3(Predicted)
solubility 
Soluble in DMSO, DCM, DMF
form 
Viscous Liquid
pka
12.23±0.46(Predicted)
color 
Colorless to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23623
Product name
DBCO-NHCO-PEG4-NH-Boc
Purity
98%
Packaging
50mg
Price
$280
Updated
2021/12/16
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DBCO-PEG4-NH-Boc Chemical Properties,Usage,Production

Description

DBCO-NHCO-PEG4-NH-Boc is a click chemistry reagent. it can undergo copper-free Click Chemistry reactions with azides. The Boc protecting group can be removed under acidic conditions.

Biological Activity

DBCO-NHCO-PEG4-NH-Boc is a PROTAC linker that belongs to the PEG class and the Alkyl/ether class. It can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs).

in vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

target

Cleavable

PEGs

Alkyl/ether

DBCO-PEG4-NH-Boc Preparation Products And Raw materials

Raw materials

Preparation Products

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DBCO-PEG4-NH-Boc Suppliers

Shanghai Send Pharmaceutical Technology Co., Ltd.
Tel
021-58088081 Q3252066219
Fax
QQ3382968513
Email
danping@shsendpharm.com
Country
China
ProdList
3130
Advantage
55
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4824
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
Shaanxi Xinyan Bomei Biotechnology Co., Ltd.
Tel
029-86217788 13892832556
Email
2440688701@qq.com
Country
China
ProdList
1993
Advantage
58
Changzhou Kechem Bio-Scientific Co., LTD.
Tel
0519-68985668 13685222090
Fax
qq735434464
Email
sales@kechem.cn
Country
China
ProdList
26028
Advantage
58
Zhengzhou Convergence Chemical Co. LTD
Tel
0371-53736046 13393710386
Fax
QQ:2853979814
Email
2853979814@qq.com
Country
China
ProdList
9984
Advantage
58
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
Tel
021-51816796-820 13611835272
Fax
021-5161 3951
Email
sales2@sunwaypharm.com
Country
China
ProdList
44458
Advantage
58
Zhengzhou Akem Chemical Co., Ltd
Tel
13303867194
Email
3001317055@qq.com
Country
China
ProdList
9992
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 4008210725
Email
malulu@leyan.com
Country
China
ProdList
40037
Advantage
58
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View Lastest Price from DBCO-PEG4-NH-Boc manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
DBCO-NHCO-PEG4-NHBoc 1255942-12-1
Price
US $0.00/mg
Min. Order
50mg
Purity
>95.00%
Supply Ability
250mg
Release date
2024-03-20

1255942-12-1, DBCO-PEG4-NH-BocRelated Search:


  • DBCO-PEG4-NH-Boc
  • DBCO-NHCO-PEG4-NH-Boc
  • DBCO-NHCO-PEG4-t-Boc Amine
  • 5,8,11,14-Tetraoxa-2,18-diazaheneicosanoic acid, 21-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-17,21-dioxo-, 1,1-dimethylethyl ester
  • 1255942-12-1
  • C34H45N3O8