ChemicalBook > CAS DataBase List > HUMAN IL-10
HUMAN IL-10
- Product Name
- HUMAN IL-10
- CAS No.
- 1924707-97-0
- Chemical Name
- HUMAN IL-10
- Synonyms
- CSIF;TGIF;IL-10;TGIF1;GVHDS;IL10A;B-TCGF;RHIL-10;HUMAN CSIF;HUMAN TGIF
- CBNumber
- CB2357601
- Formula Weight
- 0
- MOL File
- Mol file
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HUMAN IL-10 Property
- storage temp.
- −20°C
- form
- lyophilized powder
- biological source
- human
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SRP3312
- Product name
- IL-10 human
- Purity
- Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
- Packaging
- 10μG
- Price
- $412
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- SRP3071
- Product name
- IL-10 human
- Purity
- recombinant, expressed in <I>E. coli</I>, ≥98% (SDS-PAGE), suitable for cell culture
- Packaging
- 10 μg
- Price
- $335
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- I9276
- Product name
- Interleukin-10 human
- Purity
- ≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected <I>Sf</I>21 cells, lyophilized powder, suitable for cell culture
- Packaging
- 5 μg
- Price
- $544
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- H7541
- Product name
- Interleukin-10 human
- Purity
- IL-10, recombinant, expressed in HEK 293 cells, HumanKine?, suitable for cell culture
- Packaging
- 10μg
- Price
- $423
- Updated
- 2025/07/31
Usbiological
- Product number
- 493803
- Product name
- TGIF1
- Packaging
- 100ul
- Price
- $499
- Updated
- 2021/12/16
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HUMAN IL-10 Chemical Properties,Usage,Production
Uses
Interleukin-10 (IL-10) human has been used to study the effect of IL-10 on cartilage proteoglycan turnover. It has been used as an antigen to analyse the reactivity patterns of autoantibodies in healthy humans and humans suffering from type 1 diabetes mellitus.
Biological Activity
Interleukin-10 (IL-10) is an anti-inflammatory protein th at inhibits the expression of proinflammatory cytokines such as IL-1 and tumor necrosis factor-α (TNF-α). Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. It inhibits the production of IFN-γ and antigen-specific proliferation of type-1 T helper cells (Th1). It protects the host tissue from damage during immune responses. The protein has a role in modulating viral immunity. IL-10 enhances cytokine production, natural killer cell proliferation and cytotoxicity in vitro. IL-10 is an immunosuppressive cytokine. It promotes wound repair and functions to resolve inflammation in the central nervous system. IL-10 mediates its signaling function through the interleukin receptors namely, IL-10RA and two IL-10RBs. The expression of IL-10 is regulated by signal transducer and activator of transcription 3 (STAT3) and suppressor of cytokine signaling-3 (SOCS3) ratios. Polymorphisms in the IL-10 gene is implicated in breast cancer.
HUMAN IL-10 Preparation Products And Raw materials
Raw materials
Preparation Products
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