ChemicalBook > CAS DataBase List > 2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE
2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE
- Product Name
- 2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE
- CAS No.
- 111686-79-4
- Chemical Name
- 2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE
- Synonyms
- pr934-423a;fpl12924aa;RemacemideHCl;REMACEMIDE HYDROCHLORIDE;2-AMino-N-(1,2-diphenylpropan-2-yl)acetaMide hydrochloride;2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE;2-diphenylethyl)acetamidemonohydrochloride(+-)-2-amino-n-(1-methyl-;2-amino-n-(1-methyl-1,2-diphenylethyl)-,monohydrochloride,(+-)-acetamid
- CBNumber
- CB2360100
- Molecular Formula
- C17H21ClN2O
- Formula Weight
- 304.82
- MOL File
- 111686-79-4.mol
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2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE Property
- Melting point:
- 253-254°
- storage temp.
- room temp
- solubility
- H2O: >10mg/mL
- form
- powder
- color
- white to beige
- Water Solubility
- Soluble to 100 mM in water
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Safety
- Hazard Codes
- Xn,N
- Risk Statements
- 22-41-50/53
- Safety Statements
- 26-39-45-60-61
- RIDADR
- UN 3077 9 / PGIII
- WGK Germany
- 3
- RTECS
- AB4349500
- Toxicity
- LD50 (calculated as base) in rats (mg/kg): ~50 i.v., ~900 orally (Muir, Palmer)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H318Causes serious eye damage
H400Very toxic to aquatic life
- Precautionary statements
-
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML0335
- Product name
- Remacemide hydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 10mg
- Price
- $144
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- SML0335
- Product name
- Remacemide hydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 50mg
- Price
- $540
- Updated
- 2023/01/07
Tocris
- Product number
- 1622
- Product name
- Remacemide hydrochloride
- Purity
- ≥99%(HPLC)
- Packaging
- 50
- Price
- $592
- Updated
- 2021/12/16
Tocris
- Product number
- 1622
- Product name
- Remacemide hydrochloride
- Purity
- ≥99%(HPLC)
- Packaging
- 10
- Price
- $140
- Updated
- 2021/12/16
TRC
- Product number
- R143450
- Product name
- Remacemide hydrochloride
- Packaging
- 2.5mg
- Price
- $140
- Updated
- 2021/12/16
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2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
Anticonvulsant (neuroprotective).
Biological Activity
Non-competitive NMDA receptor antagonist; blocks ion channel and allosteric modulatory site (IC 50 = 8-68 mM). Anticonvulsant in vivo and metabolizes to a more potent desglycine analog. Weakly blocks voltage-dependent Na + channels (IC 50 = 161 mM).
Biochem/physiol Actions
Remacemide HCl is a low affinity NMDA antagonist with anticonvulsant properties. Remacemide also been shown to block voltage-dependent sodium channels.
2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE Suppliers
- Tel
- --
- Fax
- --
- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71
111686-79-4, 2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDERelated Search:
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2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE
Ramacemide