ANTI-HEAT SHOCK PROTEIN 70
- Product Name
- ANTI-HEAT SHOCK PROTEIN 70
- Chemical Name
- ANTI-HEAT SHOCK PROTEIN 70
- Synonyms
- hsc70;hspa8;Anti-MOT;MGC55272;Anti-CSA;Anti-MOT2;Anti-CKN1;ANTI-GRP75;ANTI-HSC70;Anti-PBP74
- CBNumber
- CB2388733
- Formula Weight
- 0
- MOL File
- Mol file
ANTI-HEAT SHOCK PROTEIN 70 Property
- storage temp.
- −20°C
- form
- buffered aqueous solution
- biological source
- rabbit
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H317May cause an allergic skin reaction
H412Harmful to aquatic life with long lasting effects
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P272Contaminated work clothing should not be allowed out of the workplace.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- SAB2701964
- Product name
- Anti-HSPA8 antibody produced in rabbit
- Packaging
- 100μL
- Price
- $512
- Updated
- 2025/07/31
- Product number
- H5147
- Product name
- Monoclonal Anti-Heat Shock Protein 70 antibody produced in mouse
- Purity
- clone BRM-22, ascites fluid
- Packaging
- 100μL
- Price
- $515
- Updated
- 2025/07/31
- Product number
- HPA000898
- Product name
- ANTI-HSPA9 antibody produced in rabbit
- Purity
- Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
- Packaging
- 100μL
- Price
- $555
- Updated
- 2025/07/31
- Product number
- H5147
- Product name
- Monoclonal Anti-Heat Shock Protein 70 antibody produced in mouse
- Purity
- clone BRM-22, ascites fluid
- Packaging
- 0.2mL
- Price
- $678
- Updated
- 2025/07/31
- Product number
- G4045
- Product name
- Anti-GRP75 (SQ-15) antibody produced in rabbit
- Purity
- ~1 mg/mL, affinity isolated antibody, buffered aqueous solution
- Packaging
- 200 μL
- Price
- $304.5
- Updated
- 2025/07/31
ANTI-HEAT SHOCK PROTEIN 70 Chemical Properties,Usage,Production
Uses
The antibody titer of at least 1:5,000 was determined by immunoblotting using bovine brain extract.
General Description
Monoclonal Anti-Heat Shock Protein 70 (mouse IgG1 isotype) is derived from the BRM-22 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with purified bovine brain HSP70. Heat shock protein family A (Hsp70) member 1A (HSPA1A), is encoded by the gene mapped to human chromosome 6p21.33. It is widely expressed in all tissues. The encoded protein is characterized with an N-terminal ATPase domain of 45 kDa and a C-terminal substrate binding domain of 25 kDa.
Biochem/physiol Actions
Members of the HSP70 family play a major role in the folding, unfolding and translocation of polypeptides as well as in the assembly and disassembly of oligomeric protein complexes. In addition, several possible roles have been attributed to the HSP70 family of proteins, in the immune response. It has been shown that alcoholic liver disease is associated with intracytoplasmic accumulation of HSP70. HSP72 was found to increase dramatically in the brains of Alzheimer′s disease patient, and was localized exclusively in neuritic plaques and neurofibrillary tangles. HSP70 concentrates in nuclei during heat shock and returns to the cytoplasm when the shock is removed.
ANTI-HEAT SHOCK PROTEIN 70 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-HEAT SHOCK PROTEIN 70 Suppliers
- Tel
- --
- Fax
- --
- solutions@vwr.com
- Country
- United Kingdom
- ProdList
- 6548
- Advantage
- 82