ChemicalBook > CAS DataBase List > (S)-2-((S)-2-amino-3-methylbutanamido)-5-ureidopentanoic acid
(S)-2-((S)-2-amino-3-methylbutanamido)-5-ureidopentanoic acid
- Product Name
- (S)-2-((S)-2-amino-3-methylbutanamido)-5-ureidopentanoic acid
- CAS No.
- 159858-33-0
- Chemical Name
- (S)-2-((S)-2-amino-3-methylbutanamido)-5-ureidopentanoic acid
- Synonyms
- Val-Cit;Val-Cit-OH;L-Ornithine, L-valyl-N5-(aminocarbonyl)-;(S)-2-((S)-2-amino-3-methylbutanamido)-5-ureidopentanoic acid;ValCit,ADC Linkers,Val Cit,Antibody-drug conjugates linkers,Inhibitor,inhibit,Val-Cit
- CBNumber
- CB24188270
- Molecular Formula
- C11H22N4O4
- Formula Weight
- 274.32
- MOL File
- 159858-33-0.mol
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(S)-2-((S)-2-amino-3-methylbutanamido)-5-ureidopentanoic acid Property
- Boiling point:
- 554.0±50.0 °C(Predicted)
- Density
- 1.218±0.06 g/cm3(Predicted)
- solubility
- Soluble in Water, DMSO, DCM, DMF
- pka
- 3.13±0.10(Predicted)
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
BroadPharm
- Product number
- BP-24335
- Product name
- Val-Cit
- Purity
- 98%
- Packaging
- 250mg
- Price
- $240
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-24335
- Product name
- Val-Cit
- Purity
- 98%
- Packaging
- 1g
- Price
- $780
- Updated
- 2021/12/16
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(S)-2-((S)-2-amino-3-methylbutanamido)-5-ureidopentanoic acid Chemical Properties,Usage,Production
Description
Val-Cit is a cleavable ADC linker used in antibody drug conjugate. The Val-Cit linker was designed to be cleaved by cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell.
Biological Activity
Val-Cit is a cleavable ADC linker that can be used to synthesize antibody-drug conjugates (ADCs).
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
target
| Cleavable
|
(S)-2-((S)-2-amino-3-methylbutanamido)-5-ureidopentanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (S)-2-((S)-2-amino-3-methylbutanamido)-5-ureidopentanoic acid manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- Val-Cit 159858-33-0
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >95.00%
- Supply Ability
- 1g
- Release date
- 2024-03-29