6-(1H-IMIDAZOL-1-YL)NICOTINIC ACID
- Product Name
- 6-(1H-IMIDAZOL-1-YL)NICOTINIC ACID
- CAS No.
- 216955-75-8
- Chemical Name
- 6-(1H-IMIDAZOL-1-YL)NICOTINIC ACID
- Synonyms
- 6-(1H-Imidazol-1-yl);6-IMIDAZOL-1-YL-NICOTINIC ACID;6-(1H-Imidazol-1-yl)nicotinicaci;6-(1H-IMIDAZOL-1-YL)NICOTINIC ACID;6-imidazol-1-ylpyridine-3-carboxylic acid;6-(1H-imidazol-1-yl)-3-Pyridine carboxylic acid;3-Pyridinecarboxylic acid, 6-(1H-imidazol-1-yl)-;Pyridine,2,4-dichloro-, 1-oxide6-(1H-IMIDAZOL-1-YL)NICOTINIC ACID;6-(1H-Imidazol-1-yl)pyridine-3-carboxylic acid, 1-(5-Carboxypyridin-2-yl)-1H-imidazole
- CBNumber
- CB2754404
- Molecular Formula
- C9H7N3O2
- Formula Weight
- 189.17
- MOL File
- 216955-75-8.mol
6-(1H-IMIDAZOL-1-YL)NICOTINIC ACID Property
- Melting point:
- >270°
- Boiling point:
- 442.5±30.0 °C(Predicted)
- Density
- 1.39±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 2.92±0.10(Predicted)
- Appearance
- White to off-white Solid
Safety
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- I577443
- Product name
- 6-(1H-Imidazol-1-yl)nicotinicAcid
- Packaging
- 500mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- CS-0130290
- Product name
- 6-(1H-Imidazol-1-yl)nicotinicacid
- Purity
- 99.87%
- Packaging
- 250mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- CS-0130290
- Product name
- 6-(1H-Imidazol-1-yl)nicotinicacid
- Purity
- 99.87%
- Packaging
- 1g
- Price
- $110
- Updated
- 2021/12/16
- Product number
- 043793
- Product name
- 6-(1H-Imidazol-1-yl)nicotinic acid
- Purity
- >95%
- Packaging
- 500mg
- Price
- $181
- Updated
- 2021/12/16
- Product number
- 4H21-1-E5
- Product name
- 6-(1H-Imidazol-1-yl)nicotinic acid
- Packaging
- 1g
- Price
- $186
- Updated
- 2021/12/16
6-(1H-IMIDAZOL-1-YL)NICOTINIC ACID Chemical Properties,Usage,Production
Synthesis
111205-01-7
216955-75-8
General procedure for the synthesis of 6-(1H-imidazol-1-yl)nicotinic acid from 6-(1H-imidazol-1-yl)nicotinic acid methyl ester: In a round-bottomed flask, 6-(1H-imidazol-1-yl)nicotinic acid methyl ester (535 mg, 2.50 mmol), tetrahydrofuran (12 mL), sodium hydroxide (780 mg, 19.50 mmol), and methanol (10 mL) were added, and the reaction was conducted at 50°C for 3 h. The reaction was heated at 50°C for 3 h. Upon completion of the reaction, the reaction mixture was acidified with 1N hydrochloric acid and subsequently concentrated to dryness under reduced pressure. The resulting solid was suspended in a mixed solvent of methanol/dichloromethane, filtered and concentrated to give 6-(1H-imidazol-1-yl)nicotinic acid as a white solid (0.47 g, 68% yield).LCMS (m/z): 190.0 (M + 1).
References
[1] Patent: WO2014/168824, 2014, A1. Location in patent: Page/Page column 39; 40
[2] Patent: WO2011/94890, 2011, A1. Location in patent: Page/Page column 130
6-(1H-IMIDAZOL-1-YL)NICOTINIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
6-(1H-IMIDAZOL-1-YL)NICOTINIC ACID Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
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View Lastest Price from 6-(1H-IMIDAZOL-1-YL)NICOTINIC ACID manufacturers
- Product
- Pyridine,2,4-dichloro-, 1-oxide6-(1H-IMIDAZOL-1-YL)NICOTINIC ACID 216955-75-8
- Price
- US $1.80/KG
- Min. Order
- 1g
- Purity
- 96%-99%
- Supply Ability
- 1kg/10kg/100kg
- Release date
- 2020-11-07