ChemicalBook > CAS DataBase List > 4-Pyrimidinecarboxamide, 5-chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)-
4-Pyrimidinecarboxamide, 5-chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)-
- Product Name
- 4-Pyrimidinecarboxamide, 5-chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)-
- CAS No.
- 873080-25-2
- Chemical Name
- 4-Pyrimidinecarboxamide, 5-chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)-
- Synonyms
- ZAP 180013;ZAP-180013 ，E0437;ZAP-180013, 10 mM in DMSO;5-Chloro-N-(4-chlorobenzyl)-2-(ethylsulfonyl)-N-(furan-2-ylmethyl)pyrimidine-4-carboxamide;4-Pyrimidinecarboxamide, 5-chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)-;Inhibitor,autoimmune,ZAP-70,tyrosine,T-cell,ZAP 180013,ZAP180013,Tyrosinase,ZAP-180013,antigen,inhibit
- CBNumber
- CB28108342
- Molecular Formula
- C19H17Cl2N3O4S
- Formula Weight
- 454.33
- MOL File
- 873080-25-2.mol
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4-Pyrimidinecarboxamide, 5-chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)- Property
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
Tocris
- Product number
- 6821
- Product name
- ZAP180013
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $105
- Updated
- 2021/12/16
Tocris
- Product number
- 6821
- Product name
- ZAP180013
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $445
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0120291
- Product name
- ZAP-180013
- Purity
- 98.56%
- Packaging
- 5mg
- Price
- $180
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0120291
- Product name
- ZAP-180013
- Purity
- 98.56%
- Packaging
- 10mg
- Price
- $300
- Updated
- 2021/12/16
Ambeed
- Product number
- A1359461
- Product name
- 5-Chloro-N-(4-chlorobenzyl)-2-(ethylsulfonyl)-N-(furan-2-ylmethyl)pyrimidine-4-carboxamide
- Purity
- 98%
- Packaging
- 1mg
- Price
- $102
- Updated
- 2021/12/16
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4-Pyrimidinecarboxamide, 5-chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)- Chemical Properties,Usage,Production
Uses
ZAP-180013 is a zeta-chain-associated protein kinase 70 (ZAP-70) inhibitor with an IC50 of 1.8 μM. ZAP-180013 inhibits the interaction of ZAP-70 SH2 domain with immunoreceptor tyrosine-based activation motif (ITAMs)[1].
storage
Store at -20°C
References
[1] Patrick R Visperas, et al. Identification of Inhibitors of the Association of ZAP-70 With the T Cell Receptor by High-Throughput Screen. SLAS Discov. 2017 Mar;22(3):324-331. DOI:10.1177/1087057116681407
4-Pyrimidinecarboxamide, 5-chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)- Preparation Products And Raw materials
Raw materials
Preparation Products
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4-Pyrimidinecarboxamide, 5-chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)- Suppliers
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873080-25-2, 4-Pyrimidinecarboxamide, 5-chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)-Related Search:
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