ChemicalBook > CAS DataBase List > IL-17A inhibitor 1
IL-17A inhibitor 1
- Product Name
- IL-17A inhibitor 1
- CAS No.
- 2452464-73-0
- Chemical Name
- IL-17A inhibitor 1
- Synonyms
- LY3509754;LY-3533028;IL-17A inhibitor 1;IL-17A inhibitor 1, 10 mM in DMSO;inhibit,Inhibitor,Interleukin Related,COPD,Asthma,IL-17A inhibitor 1,IL17A inhibitor 1,IL 17A inhibitor 1;1,2,5-Oxadiazole-3-carboxamide, N-[(S)-(4,4-difluorocyclohexyl)[7-[(1S)-2-methoxy-1-[(4S)-2-oxo-4-(trifluoromethyl)-1-imidazolidinyl]ethyl]imidazo[1,2-b]pyridazin-2-yl]methyl]-4-methyl-
- CBNumber
- CB28529477
- Molecular Formula
- C24H27F5N8O4
- Formula Weight
- 586.51
- MOL File
- 2452464-73-0.mol
More
Less
IL-17A inhibitor 1 Property
- Density
- 1?+-.0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- pka
- 11.52±0.46(Predicted)
- form
- Solid
- color
- Off-white to yellow
- InChIKey
- MVWVCLAORBNXSD-UWVAXJGDSA-N
- SMILES
- O1N=C(C)C(C(N[C@@H](C2CCC(F)(F)CC2)C2=CN3C(=N2)C=C([C@H](N2C(=O)N[C@H](C(F)(F)F)C2)COC)C=N3)=O)=N1
More
Less
IL-17A inhibitor 1 Chemical Properties,Usage,Production
Uses
LY3509754 (IL-17A inhibitor 1) is a IL-17A inhibitor, with IC50 values of <9.45 nM and 9.3 nM in alphalisa assay and HT-29 cells[1].
Biological Activity
IL-17A inhibitor 1 (example 24) is a IL-17A inhibitor, with IC50 values of <9.45 nM and 9.3 nM in alphalisa assay and HT-29 cells[1]. IL-17A inhibitor 1 (example 24) possesses high oral bioavailability (F=107%)[1].
in vivo
LY3509754 (example 24) possesses high oral bioavailability (F=107%)[1].
IC 50
IL-17
References
[1]. COATES DAVID ANDREW, et al. IMIDAZO[1,2-B]PYRIDAZINE IL-17A INHIBITORS. Patent WO2020146194.
IL-17A inhibitor 1 Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
IL-17A inhibitor 1 Suppliers
- Tel
- 4008200310
- marketing@tsbiochem.com
- Country
- China
- ProdList
- 24961
- Advantage
- 58
- Tel
- 0550-5196001 15000891977
- Fax
- 0550-5196001
- wj520wjxby@126.com
- Country
- China
- ProdList
- 1944
- Advantage
- 55
- Tel
- 021-52996696，15000506266 15000506266
- Fax
- +86-21-52996696
- Country
- China
- ProdList
- 4757
- Advantage
- 55
- Tel
- 13764913901
- Fax
- -
- info@angtibio.com
- Country
- China
- ProdList
- 4986
- Advantage
- 55
- Tel
- 021-65675885 18964387627
- Fax
- 021-65675885
- info@efebio.com
- Country
- China
- ProdList
- 9803
- Advantage
- 58
- Tel
- 021-31433387 15618786686
- Fax
- QQ:1369748377
- sales@rechemscience.com
- Country
- China
- ProdList
- 2988
- Advantage
- 58
- Tel
- 010-88886666-01 13112345678
- Fax
- CDXH21@126.com
- loyson@tcypharm.com
- Country
- China
- ProdList
- 597
- Advantage
- 55
- Tel
- 15317229551
- Fax
- QQ:3607245178
- 15151849396@163.com
- Country
- China
- ProdList
- 989
- Advantage
- 58
- Tel
- 15727060112
- yutianchun2007@126.com
- Country
- China
- ProdList
- 9814
- Advantage
- 58
- Tel
- 400-1647117 13681763483
- product02@bidepharm.com
- Country
- China
- ProdList
- 62220
- Advantage
- 58
- Tel
- 18014399201
- sales@chemlab-tachizaki.com
- Country
- China
- ProdList
- 2742
- Advantage
- 58
- Tel
- 13720134139 086-15871494362 13720134139
- orders@jknbiochem.com
- Country
- China
- ProdList
- 6614
- Advantage
- 58
- Tel
- 0513-66337626 18051384581
- sales@chemhifuture.com
- Country
- China
- ProdList
- 5929
- Advantage
- 58
- Tel
- 025-85560043 15850508050
- Fax
- 025-85563444
- cindy.huang@synzest.com
- Country
- China
- ProdList
- 12000
- Advantage
- 58
- Tel
- 0731-13823398 15111215862
- 313359644@qq.com
- Country
- China
- ProdList
- 4161
- Advantage
- 58
- Tel
- hanfangpharma@126.com; 18616537568
- hanfangpharma@126.com
- Country
- China
- ProdList
- 29965
- Advantage
- 58
- Tel
- 18024082417
- market@ubiochem.com
- Country
- China
- ProdList
- 9835
- Advantage
- 58
- Tel
- 17316404525 17316404525
- 209533805@qq.com
- Country
- China
- ProdList
- 9767
- Advantage
- 58
- Tel
- 025-58851090 17714375163
- 2881759498@qq.com
- Country
- China
- ProdList
- 13011
- Advantage
- 58
- Tel
- 13376082704 13376084917;
- 3930959291@qq.com
- Country
- China
- ProdList
- 2080
- Advantage
- 58
- Tel
- 18221172427
- sale@fine-biotech.com
- Country
- China
- ProdList
- 2772
- Advantage
- 58
- Tel
- 400-821-026
- Sales@sangon.com
- Country
- China
- ProdList
- 6710
- Advantage
- 58
- Tel
- 51288865780
- sales@biosynth.com
- Country
- China
- ProdList
- 6051
- Advantage
- 58
- Tel
- +86-0533-2185556 +8615965530500
- nickzhang@hangyubiotech.com
- Country
- China
- ProdList
- 8510
- Advantage
- 58
- Tel
- +8613720134139
- orders@jknbiochem.com
- Country
- China
- ProdList
- 5221
- Advantage
- 58
- Tel
- 13128698830
- Country
- CHINA
- ProdList
- 181
- Advantage
- 58
- Tel
- --
- Fax
- --
- chenjw@absin.cn
- Country
- CHINA
- ProdList
- 6208
- Advantage
- 58
- Tel
- --
- Fax
- --
- Proteintech-CN@ptglab.com
- Country
- CHINA
- ProdList
- 6290
- Advantage
- 58