ChemicalBook > CAS DataBase List > O-[3,5-diiodo-4-(sulfooxy)phenyl]-3,5-diiodo L-tyrosine

O-[3,5-diiodo-4-(sulfooxy)phenyl]-3,5-diiodo L-tyrosine

Product Name
O-[3,5-diiodo-4-(sulfooxy)phenyl]-3,5-diiodo L-tyrosine
CAS No.
77074-49-8
Chemical Name
O-[3,5-diiodo-4-(sulfooxy)phenyl]-3,5-diiodo L-tyrosine
Synonyms
Thyroxine sulfate;T4 Sulfate;L-Thyroxine sulfate;Thyroxine 4'-O-Sulfate;L-Thyroxine sulfate salt;Thyroxine Hydrogen Sulfate;O-[3,5-diiodo-4-(sulfooxy)phenyl]-3,5-diiodo L-tyrosine;L-Tyrosine, O-[3,5-diiodo-4-(sulfooxy)phenyl]-3,5-diiodo-
CBNumber
CB31236409
Molecular Formula
C15H11I4NO7S
Formula Weight
856.93
MOL File
77074-49-8.mol
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O-[3,5-diiodo-4-(sulfooxy)phenyl]-3,5-diiodo L-tyrosine Property

Density 
2.658±0.06 g/cm3(Predicted)
storage temp. 
Store at 4°C
solubility 
DMSO : ≥ 31 mg/mL (36.18 mM)
form 
Solid
pka
-4.80±0.18(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-6313
Product name
Thyroxinesulfate
Purity
>98.0%
Packaging
5mg
Price
$96
Updated
2021/12/16
ChemScene
Product number
CS-6313
Product name
Thyroxinesulfate
Purity
>98.0%
Packaging
10mg
Price
$144
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611751
Product name
Thyroxine sulfate
Packaging
10mg
Price
$268.6
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611751
Product name
Thyroxine sulfate
Packaging
50mg
Price
$523.6
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
62136
Product name
Thyroxine4??-O-Sulfate
Packaging
100mg
Price
$2200
Updated
2021/12/16
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O-[3,5-diiodo-4-(sulfooxy)phenyl]-3,5-diiodo L-tyrosine Chemical Properties,Usage,Production

Uses

Thyroxine 4-O-Sulfate is a metabolite and sulfoconjugated derivative of Thyroxine (T425600).

Definition

ChEBI: An iodothyronine having iodo substituents in the 3-, 3'-, 5- and 5'-positions and a sulfate group attached to the phenol function.

in vivo

Significant amounts of thyroxine sulfate (T4S) in fetal sheep serum, meconium, bile, and amniotic and allantoic fluids are observed. T4S concentration in amniotic fluid from women at 18-19 weeks of gestation (25.5 ng/dL) is higher than that at 14-15 weeks of gestation (14.3 ng/dL). A significant rise in serum T4S is detected in hyperthyroid patients 1 day after ingestion of 1 g of ipodate[1]. Thyroxine undergoes significant sulfation in rats, and biliary excretion of T4S is enhanced if its type I deiodination is inhibited[2]. Serum T4S levels are clearly elevated compared with healthy references, and the decreased deiodination by liver D1 during critical illness appears to play a role in this increase in serum T4S levels[3].

IC 50

Human Endogenous Metabolite

O-[3,5-diiodo-4-(sulfooxy)phenyl]-3,5-diiodo L-tyrosine Preparation Products And Raw materials

Raw materials

Preparation Products

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O-[3,5-diiodo-4-(sulfooxy)phenyl]-3,5-diiodo L-tyrosine Suppliers

Canada 1 China 25 United States 4 Global 30
J & K SCIENTIFIC LTD.
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View Lastest Price from O-[3,5-diiodo-4-(sulfooxy)phenyl]-3,5-diiodo L-tyrosine manufacturers

Career Henan Chemical Co
Product
O-[3,5-diiodo-4-(sulfooxy)phenyl]-3,5-diiodo L-tyrosine 77074-49-8
Price
US $1.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
100kg
Release date
2020-03-11

77074-49-8, O-[3,5-diiodo-4-(sulfooxy)phenyl]-3,5-diiodo L-tyrosineRelated Search:

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  • O-[3,5-diiodo-4-(sulfooxy)phenyl]-3,5-diiodo L-tyrosine
  • Thyroxine sulfate
  • Thyroxine 4'-O-Sulfate
  • Thyroxine Hydrogen Sulfate
  • L-Thyroxine sulfate
  • L-Tyrosine, O-[3,5-diiodo-4-(sulfooxy)phenyl]-3,5-diiodo-
  • L-Thyroxine sulfate salt
  • T4 Sulfate
  • 77074-49-8
  • C15H11I4NO7S
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  • Metabolites & Impurities
  • Pharmaceuticals
  • Sulfur & Selenium Compounds