AI 77B

Product Name: AI 77B
CAS No.: 77674-99-8
Chemical Name: AI 77B
Synonyms: AI 77B;(3S,4S,5S)-3-Amino-4,5-dihydroxy-6-oxo-6-[[(S)-1-[(S)-3,4-dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl]-3-methylbutyl]amino]hexanoic acid;D-ribo-Hexonic acid, 3-amino-2,3,6-trideoxy-6-[[(1S)-1-[(3S)-3,4-dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl]-3-methylbutyl]amino]-6-oxo-;(3S,4S,5S)-3-Amino-4,5-dihydroxy-6-oxo-6-[[(1S)-1-[(3S)-1-oxo-8-hydroxy-3,4-dihydro-1H-2-benzopyran-3-yl]-3-methylbutyl]amino]hexanoic acid
CBNumber: CB31309011
Molecular Formula: C20H28N2O8
Formula Weight: 424.44
MOL File: 77674-99-8.mol

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AI 77B Property

Melting point:: 137-138 °C
Boiling point:: 830.3±65.0 °C(Predicted)
Density: 1.381±0.06 g/cm3(Predicted)
solubility: DMSO: soluble
Methanol: soluble
pka: 3.48±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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AI 77B Chemical Properties,Usage,Production

Description

AI 77B is a pseudopeptide microbial agent with gastroprotective action.

Uses

Amicoumacin B can be produced by actinomycete, strain 04-5195T.. Amicoumacin B increases the expression of bone morphogenetic protein 2 (BMP-2). Amicoumacin B has inhibitory effect against C. violaceum (MIC = 250 μg/mL). Amicoumacin B has quorum sensing inhibitory activity, and reduces the expression of the C. violaceum operons vioA, vioB, vioD, and vioE, but increases the expression of vioC[1][2].

References

[1] Shi WP, et al. Amicoumacins from a desert bacterium: quorum sensing inhibitor against Chromobacterium violaceum. Nat Prod Res. 2021 Dec;35(23):5508-5512. DOI:10.1080/14786419.2020.1788554
[2] Sun W, et al. Nocardia jinanensis sp. nov., an amicoumacin B-producing actinomycete. Int J Syst Evol Microbiol. 2009 Feb;59(Pt 2):417-20. DOI:10.1099/ijs.0.002899-0
[3] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.

AI 77B Preparation Products And Raw materials

Raw materials

Preparation Products

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AI 77B Suppliers

China 5 United States 2 Global 7

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354;
Email: support@targetmol.com
Country: United States
ProdList: 39035
Advantage: 58

77674-99-8, AI 77BRelated Search:

1H-2-BENZOPYRAN-1-ONE, 3,4-DIHYDRO-8-HYDROXY- N-(1-METHYL-3-PHENYLPROPYL)-N-VALERAMIDE AI 77B 3-Methyl-1-phenethylbutylamine

AI 77B

(3S,4S,5S)-3-Amino-4,5-dihydroxy-6-oxo-6-[[(1S)-1-[(3S)-1-oxo-8-hydroxy-3,4-dihydro-1H-2-benzopyran-3-yl]-3-methylbutyl]amino]hexanoic acid

(3S,4S,5S)-3-Amino-4,5-dihydroxy-6-oxo-6-[[(S)-1-[(S)-3,4-dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl]-3-methylbutyl]amino]hexanoic acid

D-ribo-Hexonic acid, 3-amino-2,3,6-trideoxy-6-[[(1S)-1-[(3S)-3,4-dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl]-3-methylbutyl]amino]-6-oxo-

77674-99-8