ChemicalBook > CAS DataBase List > PC 766B

PC 766B

Product Name
PC 766B
CAS No.
108375-77-5
Chemical Name
PC 766B
Synonyms
PC 766B;Oxacyclohexadeca-3,5,11,13-tetraen-2-one, 16-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-4-[(2,6-dideoxy-β-D-arabino-hexopyranosyl)oxy]tetrahydro-2-hydroxy-5-methyl-6-[(1E,3E)-1,3-pentadien-1-yl]-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-, (3Z,5E,7R,8S,9S,11E,13E,15S,16R...
CBNumber
CB31333205
Molecular Formula
C43H68O12
Formula Weight
776.99
MOL File
108375-77-5.mol
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PC 766B Property

storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
20587
Product name
PC-766B
Purity
≥95%
Packaging
1mg
Price
$275
Updated
2024/03/01
Cayman Chemical
Product number
20587
Product name
PC-766B
Purity
≥95%
Packaging
5mg
Price
$1026
Updated
2024/03/01
TRC
Product number
P216603
Product name
PC-766B
Packaging
1mg
Price
$195
Updated
2021/12/16
TRC
Product number
P216603
Product name
PC-766B
Packaging
2.5mg
Price
$385
Updated
2021/12/16
ApexBio Technology
Product number
C4269
Product name
PC-766B
Packaging
1mg
Price
$312
Updated
2021/12/16
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PC 766B Chemical Properties,Usage,Production

Description

PC-766B is a macrolide antibiotic produced by N. brasiliensis that is active against Gram-positive bacteria and some fungi, yet inactive against Gram-negative bacteria. It also demonstrates antitumor activity against mouse P388 leukemia and B16 melanoma cells in vitro (IC50s = 0.1 and 0.4 ng/ml, respectively) and in vivo, but weakly inhibits the Na+,K+-ATPase compared to structurally related antibiotics.

Uses

PC-766B is a 16-membered macrolide antibiotic produced by Nocardia brasiliensis, reported by researchers at Sumitomo in 1993. Structurally, PC-766B is a member of bafilomycin class, featuring a rare butadiene side-chain. PC-766B is active against Gram positive bacteria, and some fungi and yeasts, but is inactive against Gram negative bacteria. It shows activity against murine tumor cells in vitro and in vivo, and weak inhibitory activity against Na/K-ATPase in vitro.

Uses

PC-766B is an antibiotic with activity against gram positive bacteria and some fungi and yeasts.

IC 50

Macrolide

References

[1] kumagai k, taya k, fukui a, et al. pc-766b, a new macrolide antibiotic produced by nocardia brasiliensis[j]. the journal of antibiotics, 1993, 46(6): 972-978.

PC 766B Preparation Products And Raw materials

Raw materials

Preparation Products

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PC 766B Suppliers

China 25 India 1 United Kingdom 1 United States 5 Global 32
Lynnchem
Tel
86-(0)29-85992781 17792393971
Email
info@lynnchem.com
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China
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4587
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
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sales@rrkchem.com
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China
ProdList
57422
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58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
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China
ProdList
11218
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58
Meng Cheng Technology (Shanghai) Co., LTD
Tel
400-820-6829
Email
sales@mitachieve.com
Country
China
ProdList
8860
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58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
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58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
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58
Shanghai Saikerui Biotechnology Co. , Ltd.
Tel
021-58000709 15900491054
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info@scrbio.com
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China
ProdList
9881
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Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
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China
ProdList
11973
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Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 15850508050
Fax
025-85563444
Email
cindy.huang@synzest.com
Country
China
ProdList
12000
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Hubei Danding Pharmaceutical Technology Co., Ltd
Tel
17701422019
Email
1559451077@qq.com
Country
China
ProdList
8171
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58
Shanghai Weiyite Biotechnology Co., Ltd
Tel
15317051735
Email
zhaojing@wytsci.com
Country
China
ProdList
9980
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58
Cayman Chemical Company
Tel
800-364-9897
Email
sales@caymanchem.com
Country
China
ProdList
6838
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58
Santa Cruz Biotechnology Inc
Tel
021-60936350
Email
scbt@scbt.com
Country
China
ProdList
6594
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58
Guangzhou Qingyan Biotechnology Co., Ltd.
Tel
19802084049
Country
CHINA
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171
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Neobioscience Co., Ltd.
Tel
--
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Absin Bioscience Inc.
Tel
--
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chenjw@absin.cn
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CHINA
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6208
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Shanghai Hao Zhun Biological Technology Co., Ltd.
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info@zzsrm.com
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6650
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Beijing Sizhengbai Biotechnology Co., Ltd.
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marketing@4abio.com
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CHINA
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6401
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Beijing Dongge Boye Biotechnology Co., Ltd.
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1861586486@qq.com
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Shanghai Bosheng Biotechnology Co., Ltd.
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1310057982@qq.com
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790
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Boao Pike
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lyn@biopike.com.cn
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Beijing Fubo Biotechnology Co., Ltd.
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info@f-biology.com
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6170
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Shanghai Weiwei Biological Technology Co., Ltd.
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sales@wheybio.com
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Morning Student Science and Technology (Guangzhou) Co., Ltd.
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Shanghai Hao Biological Technology Co., Ltd.
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108375-77-5, PC 766BRelated Search:


  • PC 766B
  • Oxacyclohexadeca-3,5,11,13-tetraen-2-one, 16-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-4-[(2,6-dideoxy-β-D-arabino-hexopyranosyl)oxy]tetrahydro-2-hydroxy-5-methyl-6-[(1E,3E)-1,3-pentadien-1-yl]-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-, (3Z,5E,7R,8S,9S,11E,13E,15S,16R...
  • 108375-77-5
  • C43H68O12