1-(2-Chloroethoxy)-4-nitrobenzene
- Product Name
- 1-(2-Chloroethoxy)-4-nitrobenzene
- CAS No.
- 3383-72-0
- Chemical Name
- 1-(2-Chloroethoxy)-4-nitrobenzene
- Synonyms
- β-chloro-4-nitrophenethole;BETA-CHLORO-4-NITROPHENETHOLE;4-(2-Chloroethoxy)nitrobenzene;2-(4-NITROPHENOXY)ETHYL CHLORIDE;4-Nitro-1-(2-chloroethoxy)benzene;1-(2-CHLOROETHOXY)-4-NITROBENZENE;2-CHLOROETHYL-4-NITROPHENYL ETHER;Benzene, 1-(2-chloroethoxy)-4-nitro-;1-(2-Chloroethoxy)-4-nitrobenzene,97%;1-(2-CHLOROETHOXY)4-NITROBENZENE, 98+%
- CBNumber
- CB3136632
- Molecular Formula
- C8H8ClNO3
- Formula Weight
- 201.61
- MOL File
- 3383-72-0.mol
1-(2-Chloroethoxy)-4-nitrobenzene Property
- Melting point:
- 67-68 °C
- Boiling point:
- 204-206 °C(Press: 25 Torr)
- Density
- 1.316±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder to crystal
- color
- White to Light yellow
- InChI
- InChI=1S/C8H8ClNO3/c9-5-6-13-8-3-1-7(2-4-8)10(11)12/h1-4H,5-6H2
- InChIKey
- OBCFOPGCTNULTG-UHFFFAOYSA-N
- SMILES
- C1(OCCCl)=CC=C([N+]([O-])=O)C=C1
- CAS DataBase Reference
- 3383-72-0(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- C3523
- Product name
- 1-(2-Chloroethoxy)-4-nitrobenzene
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $78
- Updated
- 2025/07/31
- Product number
- C3523
- Product name
- 1-(2-Chloroethoxy)-4-nitrobenzene
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $233
- Updated
- 2025/07/31
- Product number
- C377265
- Product name
- 1-(2-Chloroethoxy)-4-nitrobenzene
- Packaging
- 500mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- HCH0014958
- Product name
- 1-(2-CHLOROETHOXY)-4-NITROBENZENE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $194.25
- Updated
- 2021/12/16
- Product number
- OR0967
- Product name
- 1-(2-Chloroethoxy)-4-nitrobenzene
- Packaging
- 1g
- Price
- $196
- Updated
- 2021/12/16
1-(2-Chloroethoxy)-4-nitrobenzene Chemical Properties,Usage,Production
Synthesis
100-02-7
107-04-0
3383-72-0
1-(2-Chloroethoxy)-4-nitrobenzene was synthesized as follows: cesium carbonate (28.7 mmol) was added to a solution of 4-nitrophenol (28.7 mmol) in anhydrous ethanol (15 mL), followed by 1-bromo-2-chloroethane (86.2 mmol). The reaction mixture was heated to reflux at 80 °C for 8 hours. Upon completion of the reaction, the mixture was cooled, the reaction was quenched with water and extracted with ethyl acetate (EtOAc). The organic layers were combined, washed sequentially with water and brine, dried over anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure to give an orange residue. Grinding of the residue with ethanol (EtOH) gave 1-(2-chloroethoxy)-4-nitrobenzene in 66% yield. Mass spectrum (MS) (m/z): (M+1)+ 202.2.
References
[1] Patent: WO2007/38669, 2007, A2. Location in patent: Page/Page column 170
[2] Journal of Medicinal Chemistry, 2006, vol. 49, # 16, p. 4981 - 4991
[3] Patent: WO2005/68452, 2005, A1. Location in patent: Page/Page column 41
[4] Journal of Medicinal Chemistry, 2008, vol. 51, # 6, p. 1637 - 1648
[5] Patent: WO2004/5282, 2004, A1. Location in patent: Page 39
1-(2-Chloroethoxy)-4-nitrobenzene Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-(2-Chloroethoxy)-4-nitrobenzene manufacturers
- Product
- 1-(2-Chloroethoxy)-4-nitrobenzene 3383-72-0
- Price
- US $0.10/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 1000 tons
- Release date
- 2020-04-24
- Product
- 1-(2-Chloroethoxy)-4-nitrobenzene 3383-72-0
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- JD 534
- Release date
- 2019-09-01