5-Methoxycanthinone
- Product Name
- 5-Methoxycanthinone
- CAS No.
- 15071-56-4
- Chemical Name
- 5-Methoxycanthinone
- Synonyms
- Alkaloid PA-1;5-Methoxycanthinone;Methoxycanthinone, 5-;5-Methoxycanthin-6-one;5-Methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one;6H-Indolo[3,2,1-de][1,5]naphthyridin-6-one,5-methoxy-
- CBNumber
- CB32326026
- Molecular Formula
- C15H10N2O2
- Formula Weight
- 250.25
- MOL File
- 15071-56-4.mol
5-Methoxycanthinone Property
- Boiling point:
- 397.4±42.0 °C(Predicted)
- Density
- 1.40±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: Soluble
Methanol: Soluble - pka
- 3.96±0.20(Predicted)
- form
- A solid
- EPA Substance Registry System
- 5-Methoxycanthin-6-one (15071-56-4)
N-Bromosuccinimide Price
- Product number
- CFN92362
- Product name
- 5-Methoxycanthin-6-one
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $498
- Updated
- 2021/12/16
5-Methoxycanthinone Chemical Properties,Usage,Production
Uses
5-Methoxycanthin-6-one is an orally active inhibitor of Leishmania strains. 5-Methoxycanthin-6-one shows cytotoxicity with an IC50 of 5.44 μg/mL against Ailanthus altissima cells[1][2].
Definition
ChEBI: 5-Methoxycanthin-6-one is an alkaloid and an organic heterotetracyclic compound.
IC 50
Leishmania
References
[1] Ferreira ME, et al. Leishmanicidal activity of two canthin-6-one alkaloids, two major constituents of Zanthoxylum chiloperone var. angustifolium. J Ethnopharmacol. 2002 May;80(2-3):199-202. DOI:10.1016/s0378-8741(02)00025-9
[2] Anderson LA, et al. Production of cytotoxic canthin-6-one alkaloids by Ailanthus altissima plant cell cultures. J Nat Prod. 1983 May-Jun;46(3):374-8. DOI:10.1021/np50027a014
[3] ZHIHONG XU. Anti-HIV Agents 45 1 and Antitumor Agents 205. 2 Two New Sesquiterpenes, Leitneridanins A and B, and the Cytotoxic and Anti-HIV Principles from Leitneria floridana[J]. Journal of Natural Products , 2000, 63 12: 1712-1715. DOI: 10.1021/np000260u
[4] G. CEBRIÁN-TORREJÓN. The antiplasmodium effects of a traditional South American remedy: Zanthoxylum chiloperone var. angustifolium against chloroquine resistant and chloroquine sensitive strains of Plasmodium falciparum[J]. Revista Brasileira De Farmacognosia-brazilian Journal of Pharmacognosy, 2011, 14 1: 652-661. DOI: 10.1590/s0102-695x2011005000104
5-Methoxycanthinone Preparation Products And Raw materials
Raw materials
Preparation Products
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