(R)-tert-butyl 1-hydroxybut-3-en-2-ylcarbaMate

Product Name: (R)-tert-butyl 1-hydroxybut-3-en-2-ylcarbaMate
CAS No.: 89985-86-4
Chemical Name: (R)-tert-butyl 1-hydroxybut-3-en-2-ylcarbaMate
Synonyms: (R)-2-(Boc-amino)-3-buten-1-ol;(R)-tert-butyl 1-hydroxybut-3-en-2-ylcarbaMate;tert-Butyl (1R)-1-(hydroxymethyl)prop-2-enylcarbamate;tert-Butyl [(1R)-1-(hydroxymethyl)prop-2-en-1-yl]carbamate;Carbamic acid, N-[(1R)-1-(hydroxymethyl)-2-propen-1-yl]-, 1,1-dimethylethyl ester
CBNumber: CB32546136
Molecular Formula: C9H17NO3
Formula Weight: 187.24
MOL File: 89985-86-4.mol

More

Less

(R)-tert-butyl 1-hydroxybut-3-en-2-ylcarbaMate Property

Boiling point:: 302.9±35.0 °C(Predicted)
Density: 1.026±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 11.60±0.46(Predicted)
Appearance: Colorless to off-white Solid
InChI: InChI=1S/C9H17NO3/c1-5-7(6-11)10-8(12)13-9(2,3)4/h5,7,11H,1,6H2,2-4H3,(H,10,12)/t7-/m1/s1
InChIKey: HYVYNSIWYIWTCK-SSDOTTSWSA-N
SMILES: C(OC(C)(C)C)(=O)N[C@@H](CO)C=C

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

ChemScene

Product number: CS-W000577
Product name: (R)-tert-butyl(1-hydroxybut-3-en-2-yl)carbamate
Packaging: 100mg
Price: $259
Updated: 2021/12/16

AK Scientific

Product number: 1883AQ
Product name: (R)-tert-butyl(1-hydroxybut-3-en-2-yl)carbamate
Packaging: 100mg
Price: $414.8
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CCH0033074
Product name: (R)-TERT-BUTYL-(1-HYDROXYBUT-3-EN-2-YL)CARBAMATE
Purity: 95.00%
Packaging: 5MG
Price: $499.96
Updated: 2021/12/16

Chemenu

Product number: CM194718
Product name: tert-butyl(R)-(1-hydroxybut-3-en-2-yl)carbamate
Purity: 95%
Packaging: 1g
Price: $611
Updated: 2021/12/16

Crysdot

Product number: CD13001742
Product name: (R)-tert-Butyl(1-hydroxybut-3-en-2-yl)carbamate
Purity: 95+%
Packaging: 1g
Price: $640
Updated: 2021/12/16

More

Less

(R)-tert-butyl 1-hydroxybut-3-en-2-ylcarbaMate Chemical Properties,Usage,Production

Synthesis

115378-31-9

89985-86-4

General procedure for the synthesis of tert-butyl (R)-(1-hydroxybut-3-en-2-yl)carbamate from (R)-N-Boc-2,2-dimethyl-4-vinyl oxazolidine: vinyl oxazolidine 11 (500 mg, 2.2 mmol) was dissolved in ethanol (10 mL) under ice-bath cooling conditions, and p-toluenesulfonic acid monohydrate (42 mg, 0.22 mmol). The reaction mixture was stirred at room temperature for 24 hours. Upon completion of the reaction, the reaction was quenched with aqueous sodium bicarbonate and extracted with ethyl acetate (3 x 10 mL). The organic phases were combined, washed sequentially with saturated aqueous sodium bicarbonate (2 x 10 mL) and brine (10 mL), dried over anhydrous sodium sulfate, and concentrated under reduced pressure. The crude product was purified by column chromatography (eluent: hexane-ethyl acetate, v/v 9:1) to give 330 mg (80% yield) of colorless oily target compound. The 1H NMR and 13C NMR spectra of the product were in agreement with literature data [59]. Infrared spectra (ATR, cm?1) ν: 3344, 2998, 2932, 1692, 1522, 1366, 1171, 1053; 1H NMR (400 MHz, CDCl3) δ: 5.81 (m, 1H, =CH?), 5.25 (m, 2H, =CH2), 4.94 (br s, 1H, NH), 4.25 ( br s, 1H, CH?N), 3.65 (m, 2H, CH2?OH), 2.39 (br s, 1H, OH), 1.46 (s, 9H, Boc); 13C NMR (100 MHz, CDCl3) δ: 156.0, 135.4, 116.6, 79.8, 65.2, 54.7, 28.3; high-resolution mass spectra ( ESI): calculated value C9H17NO3Na [M+Na]+ m/z 210.1106, measured value 210.1109.

References

[1] Synthesis, 1994, # 12, p. 1463 - 1466
[2] Chemical Communications, 1999, # 3, p. 245 - 246
[3] Tetrahedron, 2018, vol. 74, # 38, p. 5392 - 5398
[4] Journal of Organic Chemistry, 2009, vol. 74, # 22, p. 8852 - 8855
[5] Synthesis, 1994, # 1, p. 31 - 33

(R)-tert-butyl 1-hydroxybut-3-en-2-ylcarbaMate Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

(R)-tert-butyl 1-hydroxybut-3-en-2-ylcarbaMate Suppliers

China 27 India 1 United States 2 Global 30

Shaanxi Yikunte Pharmaceutical Technology Co., Ltd.

Tel: 18049260030 18049260030
Email: 380381031@qq.com
Country: China
ProdList: 500
Advantage: 58

Tetranov Biopharm

Tel: 13526569071
Email: sales@leadmedpharm.com
Country: China
ProdList: 7892
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

BioPharmaMatrix,Inc.

Tel: 0510-86010668
Fax: 0510-86010668
Email: sales@biopharmamatrix.com
Country: China
ProdList: 4739
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Chengdu Focus Pharmaceutical Technology Co., Ltd.

Tel: 028-64950838 17340131597
Email: bd-focus@focuspharm.com
Country: China
ProdList: 850
Advantage: 58

Aikon International Limited

Tel: 025-58851090 15955137747
Fax: (6)02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15949
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Chengdu Feibai Pharmaceutical Co., Ltd.

Tel: 028-84641798 18782128315
Email: 3302391190@qq.com
Country: China
ProdList: 9797
Advantage: 55

Blocksynth Pharmaceutical Technology Co.,Ltd

Tel: 0086-19817745290; +8619817745290
Email: bd@blocksynth.com
Country: China
ProdList: 5661
Advantage: 58

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Email: sales@accelachem.com
Country: China
ProdList: 10467
Advantage: 58

Shanghai Yanze Chemical Co., Ltd.

Tel: 021-021-13773155751 19975051755
Email: 260924549@qq.com
Country: China
ProdList: 10524
Advantage: 58

Zhengzhou anmousse chemical products co. LTD

Tel: 0371-55289822 18737195735
Fax: QQ:483339295
Email: 483339295@qq.com
Country: China
ProdList: 7587
Advantage: 58

Zhengzhou Convergence Chemical Co. LTD

Tel: 0371-0371-53736046 13393710386
Fax: QQ:2853979814
Email: 2853979814@qq.com
Country: China
ProdList: 9947
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 62220
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39653
Advantage: 58

Chengdu Dorher Pharmaceutical CO.,Ltd

Tel: 028-64259743; 19983537320
Email: bd-focus@focuspharm.com
Country: China
ProdList: 682
Advantage: 58

Pushan Industry (Shaanxi) Co., Ltd.

Tel: 029-81310890 13571859809
Email: info@pushanshiye.com
Country: China
ProdList: 9953
Advantage: 58

Shanghai Haohong Scientific Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50751
Advantage: 58

Shanghai Jieshikai Biotechnology Co. , Ltd.

Tel: 021-57520305 13795461237
Email: zhuruyan@jskchem.com
Country: China
ProdList: 49234
Advantage: 58

Ningbo Zhenyue Pharmaceutical Technology Co., Ltd

Tel: 19817745290
Email: bd@blocksynth.com
Country: China
ProdList: 5869
Advantage: 58

Baoji Didu Pharmaceutical and Chemical Co., Ltd

Tel: 029-029-81148929 17791530722
Email: 1049@dideu.com
Country: China
ProdList: 10011
Advantage: 58

Tianjin Xinkangyou Biotechnology Co., LTD

Tel: 19922659386
Email: niuli@tjxkys.cn
Country: China
ProdList: 2995
Advantage: 58

Shandong Dongde New Materials Co., Ltd

Tel: 15666167041
Email: 15666167041@163.com
Country: China
ProdList: 2994
Advantage: 58

Shanghai Shengxiu Biotechnology Co., Ltd.

Tel: 13761144602
Email: 3896578657@qq.com
Country: China
ProdList: 4483
Advantage: 58

Shanghai Lee Feng Co.,Ltd

Tel: 021-13681628734 13681628734
Email: 13681628734@163.com
Country: China
ProdList: 500
Advantage: 58

89985-86-4, (R)-tert-butyl 1-hydroxybut-3-en-2-ylcarbaMateRelated Search:

3-Hydroxybutyric acid

(R)-tert-butyl 1-hydroxybut-3-en-2-ylcarbaMate

(R)-2-(Boc-amino)-3-buten-1-ol

tert-Butyl [(1R)-1-(hydroxymethyl)prop-2-en-1-yl]carbamate

Carbamic acid, N-[(1R)-1-(hydroxymethyl)-2-propen-1-yl]-, 1,1-dimethylethyl ester

tert-Butyl (1R)-1-(hydroxymethyl)prop-2-enylcarbamate

89985-86-4