4-PyriMidinaMine, 6-chloro-2-(2-pyridinyl)-
- Product Name
- 4-PyriMidinaMine, 6-chloro-2-(2-pyridinyl)-
- CAS No.
- 1014720-73-0
- Chemical Name
- 4-PyriMidinaMine, 6-chloro-2-(2-pyridinyl)-
- Synonyms
- PyriMidinaMine, 6-chloro-2-(2-pyridinyl)-;6-Chloro-2-(pyridin-2-yl)pyrimidin-4-amine;6-chloro-2-pyridin-2-yl-pyrimidin-4-ylamine;4-PyriMidinaMine, 6-chloro-2-(2-pyridinyl)-;6-chloro-2-(2-pyridin-2-yl)pyriMidin-4-ylaMine
- CBNumber
- CB32624599
- Molecular Formula
- C9H7ClN4
- Formula Weight
- 206.63
- MOL File
- 1014720-73-0.mol
4-PyriMidinaMine, 6-chloro-2-(2-pyridinyl)- Property
- Boiling point:
- 296.4±22.0 °C(Predicted)
- Density
- 1.390±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 0.77±0.10(Predicted)
Safety
- HS Code
- 2933599590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 1669DC
- Product name
- 6-Chloro-2-(pyridin-2-yl)pyrimidin-4-amine
- Packaging
- 100mg
- Price
- $145
- Updated
- 2021/12/16
- Product number
- OR350451
- Product name
- 6-Chloro-2-(pyridin-2-yl)pyrimidin-4-amine
- Packaging
- 250mg
- Price
- $177
- Updated
- 2021/12/16
- Product number
- 1669DC
- Product name
- 6-Chloro-2-(pyridin-2-yl)pyrimidin-4-amine
- Packaging
- 250mg
- Price
- $188
- Updated
- 2021/12/16
- Product number
- 3H30-5-5F
- Product name
- 6-Chloro-2-(pyridin-2-yl)pyrimidin-4-amine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $210
- Updated
- 2021/12/16
- Product number
- 1669DC
- Product name
- 6-Chloro-2-(pyridin-2-yl)pyrimidin-4-amine
- Packaging
- 1g
- Price
- $369
- Updated
- 2021/12/16
4-PyriMidinaMine, 6-chloro-2-(2-pyridinyl)- Chemical Properties,Usage,Production
Synthesis
10235-65-1
1014720-73-0
67-63-0
General procedure for the synthesis of 2-(2-pyridyl)-6-chloro-4-amino pyrimidine from 4,6-dichloro-2-(2-pyridyl)pyrimidine: 4,6-dichloro-2-(2-pyridyl)pyrimidine (210 mg, 0.93 mmol) was dissolved in ethanol (2 ml) in a microwave reaction tube. NH4OH (35% aqueous solution, 2.0 ml, 18.58 mmol) was added to this solution. The reaction mixture was heated in a microwave reactor at 100°C for 30 min. After completion of the reaction, the mixture was concentrated under vacuum. Purification was carried out by grinding the residue and washing with isopropanol to afford 2-(2-pyridyl)-6-chloro-4-aminopyrimidine (135 mg, 70% yield).
References
[1] Patent: US2012/202806, 2012, A1
4-PyriMidinaMine, 6-chloro-2-(2-pyridinyl)- Preparation Products And Raw materials
Raw materials
Preparation Products
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