ChemicalBook > CAS DataBase List > 2-Pentenoic acid, 5-(4-chlorophenyl)-3-phenyl-, (2E)-
2-Pentenoic acid, 5-(4-chlorophenyl)-3-phenyl-, (2E)-
- Product Name
- 2-Pentenoic acid, 5-(4-chlorophenyl)-3-phenyl-, (2E)-
- CAS No.
- 1180676-33-8
- Chemical Name
- 2-Pentenoic acid, 5-(4-chlorophenyl)-3-phenyl-, (2E)-
- Synonyms
- PS47;PS47;PS 47;PS47 ，E2816;PS47, 10 mM in DMSO;(E)-5-(4-Chlorophenyl)-3-phenylpent-2-enoic acid;2-Pentenoic acid, 5-(4-chlorophenyl)-3-phenyl-, (2E)-;PS47,control,inhibit,Inhibitor,PS48,PDK-1,negative,E-isomer
- CBNumber
- CB32667466
- Molecular Formula
- C17H15ClO2
- Formula Weight
- 286.75
- MOL File
- 1180676-33-8.mol
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2-Pentenoic acid, 5-(4-chlorophenyl)-3-phenyl-, (2E)- Property
- Melting point:
- 117-118 °C
- Boiling point:
- 444.1±24.0 °C(Predicted)
- Density
- 1.225±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : 100 mg/mL (348.74 mM; Need ultrasonic)
- form
- Solid
- pka
- 4.55±0.10(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
TRC
- Product number
- C609970
- Product name
- (E)-5-(4-Chlorophenyl)-3-phenylpent-2-enoicAcid
- Packaging
- 1mg
- Price
- $60
- Updated
- 2021/12/16
TRC
- Product number
- C609970
- Product name
- (E)-5-(4-Chlorophenyl)-3-phenylpent-2-enoicAcid
- Packaging
- 5mg
- Price
- $200
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- KIN0000946
- Product name
- PS47
- Purity
- 99.00%
- Packaging
- 10MG
- Price
- $238.35
- Updated
- 2021/12/16
Axon Medchem
- Product number
- Axon1664
- Product name
- PS47
- Purity
- 99%
- Packaging
- 10mg
- Price
- $99
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-20345
- Product name
- (E)-5-(4-chlorophenyl)-3-phenylpent-2-enoicacid
- Purity
- 96%
- Packaging
- 500mg
- Price
- $450
- Updated
- 2021/12/16
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2-Pentenoic acid, 5-(4-chlorophenyl)-3-phenyl-, (2E)- Chemical Properties,Usage,Production
Uses
PS47 is an inactive E-isomer of PS48. PS48 is an activator of PDK1. PS47 can be used as a negative control for PS48[1][2].
References
[1] Hindie V, et, al. Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1. Nat Chem Biol. 2009 Oct;5(10):758-64. DOI:10.1038/nchembio.208
[2] Pastor-Flores D, et, al. PIF-pocket as a target for C. albicans Pkh selective inhibitors. ACS Chem Biol. 2013 Oct 18;8(10):2283-92. DOI:10.1021/cb400452z
2-Pentenoic acid, 5-(4-chlorophenyl)-3-phenyl-, (2E)- Preparation Products And Raw materials
Raw materials
Preparation Products
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