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2-Nitro-1-naphthol

Product Name
2-Nitro-1-naphthol
CAS No.
607-24-9
Chemical Name
2-Nitro-1-naphthol
Synonyms
2-Nitro-1-Napthol;2-Nitro-2-naphthol;2-Nitronaphth-1-ol;2-NITRO-1-NAPHTHOL;2-Nitro-1-naphthol 95%;2-Nitro-1-naphthol,98%;2-Nitronaphthalen-1-ol;1-Naphthalenol, 2-nitro-;(S)-1-[()-2-(di-tert.-Butylphosphino)ferrocenylethylbis(2-
CBNumber
CB3300992
Molecular Formula
C10H7NO3
Formula Weight
189.17
MOL File
607-24-9.mol
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2-Nitro-1-naphthol Property

Melting point:
123-125 °C (lit.)
Boiling point:
324.41°C (rough estimate)
Density 
1.3175 (rough estimate)
refractive index 
1.5400 (estimate)
storage temp. 
Sealed in dry,Room Temperature
form 
Powder
pka
6.13±0.50(Predicted)
InChI
InChI=1S/C10H7NO3/c12-10-8-4-2-1-3-7(8)5-6-9(10)11(13)14/h1-6,12H
InChIKey
MUCCHGOWMZTLHK-UHFFFAOYSA-N
SMILES
C1(O)=C2C(C=CC=C2)=CC=C1[N+]([O-])=O
CAS DataBase Reference
607-24-9(CAS DataBase Reference)
NIST Chemistry Reference
2-Nitro-1-naphthol(607-24-9)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39-24/25-36
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29089990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
161152
Product name
2-Nitro-1-naphthol
Purity
95%
Packaging
5g
Price
$258
Updated
2024/03/01
TRC
Product number
N496858
Product name
2-Nitro-1-naphthol
Packaging
50mg
Price
$45
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK360787
Product name
2-Nitro-1-naphthol
Purity
98%
Packaging
1g
Price
$20
Updated
2021/12/16
SynQuest Laboratories
Product number
4654-1-V6
Product name
2-Nitro-1-naphthol
Packaging
1g
Price
$29
Updated
2021/12/16
ChemScene
Product number
CS-W007968
Product name
2-Nitro-1-naphthol
Purity
>97.0%
Packaging
10g
Price
$49
Updated
2021/12/16
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2-Nitro-1-naphthol Chemical Properties,Usage,Production

Description

2-Nitro-1-naphthol is an important organic compound with anti-inflammatory properties used as an analytical method for measuring albumin concentration and as an enzyme-labelled substrate in electrochemical immunoassays. The substance reacts with albumin to form a coloured complex which can be detected spectrophotometrically. It is also used as a model system for the study of inflammatory diseases and inhibits p38 kinase activity. In addition, a derivative of 2-Nitro-1-naphthol (4-nitro-1-naphthol) can be used to prepare chromogenic substrates for neutral or slightly acidic hydrolases.

Chemical Properties

yellow-green to ochre-brown powder and/or chunks

Uses

2-Nitro-1-naphthol was employed as substrate for use in an amperometric 3-electrode system for the determination of alkaline phosphatase, the enzyme label most commonly used in electrochemical immunoassays. It was also used in the preparation of:

  • di-(2-nitro-1-naphthyl) hydrogen phosphate
  • 1-(2′-methyl-3′-indenyl)-2-naphthylamine and -2-naphthol (axially chiral ligands)

Application

2-Nitro-1-naphthol is commonly used as an intermediate in organic synthesis. It is a derivative of 1-nitro-2-naphthol and 4-nitro-1-naphthol. 1-Nitro-2-naphthol has been found to be a potent inhibitor of enzyme-dependent activation of acetyl-CoA, while 4-nitro-1-naphthol facilitates the preparation of chromogenic substrates for neutral or slightly acidic hydrolases[1-2].

Purification Methods

Crystallise the naphthol (repeatedly) from EtOH. [Beilstein 6 H 615, 6 III 2938, 6 IV 4236.]

References

[1] JIZHENG DANG . Chromogenic substrate from 4-nitro-1-naphthol for hydrolytic enzyme of neutral or slightly acidic optimum pH: 4-Nitro-1-naphthyl-β-d-galactopyranoside as an example[J]. Bioorganic & Medicinal Chemistry Letters, 2013. DOI:10.1016/j.bmcl.2012.11.120.
[2] ATSUKO SHINOHARA. Inhibition of acetyl-coenzyme A dependent activation of N-hydroxyarylamines by phenolic compounds, pentachlorophenol and 1-nitro-2-naphthol[J]. Chemico-Biological Interactions, 1986. DOI:10.1016/0009-2797(86)90058-X.

2-Nitro-1-naphthol Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Nitro-1-naphthol Suppliers

Suzhou Shanyang Pharmaceutical Technology Co.,
Tel
0512-63268889 18506119477
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82169840@qq.com
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China
ProdList
529
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58
Zhengzhou BenHe Chemical Products Co., Ltd.,
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17703858868
Email
1819929654@qq.com
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China
ProdList
288
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50
Suzhou Zuohanhong New Materials Technology Co., Ltd
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0512-0512-13285100231 13285100231
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1119276773@qq.com
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China
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SuZhou Nahsor PharmTec Co.,Ltd
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13482028355
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46630809@qq.com
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China
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SiChuang NanBu Honesty Technology Co., Ltd.
Tel
0838-5675166 15883665058
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0838-5675535
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nbcxkj@126.com
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China
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J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
Fax
86-10-82849933
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jkinfo@jkchemical.com
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China
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94657
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Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
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86-21-61259102
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market03@meryer.com
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China
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40228
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Beijing HwrkChemical Technology Co., Ltd
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010-89508211 18501085097
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010-89508210
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sales.bj@hwrkchemical.com
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China
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Energy Chemical
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021-021-58432009 400-005-6266
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021-58436166
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sales8178@energy-chemical.com
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China
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Beijing Ouhe Technology Co., Ltd
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010-82967028 13552068683
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+86-10-82967029
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2355560935@qq.com
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China
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12390
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View Lastest Price from 2-Nitro-1-naphthol manufacturers

Henan Fengda Chemical Co., Ltd
Product
2-Nitro-1-naphthol 607-24-9
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%, 99.5% Sublimated
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-30
Henan Aochuang Chemical Co.,Ltd.
Product
2-Nitro-1-naphthol 607-24-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-28
Honest Joy Holdings Limited
Product
2-Nitro-1-naphthol 607-24-9
Price
US $0.00/KG
Min. Order
1KG
Purity
97.4%
Supply Ability
100 tons
Release date
2022-02-21

607-24-9, 2-Nitro-1-naphtholRelated Search:


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