ChemicalBook > CAS DataBase List > N-EPSILON-ACETYL-L-LYSINE

N-EPSILON-ACETYL-L-LYSINE

Product Name
N-EPSILON-ACETYL-L-LYSINE
CAS No.
692-04-6
Chemical Name
N-EPSILON-ACETYL-L-LYSINE
Synonyms
H-LYS(AC)-OH;N-epsilon-acetyllysine;lys(ac);N6-Acetyllysine;N-EPSILON-ACETYL-L-LYS;NSC 102777;LYSINE(AC)-OH;H-L-LYS(AC)-OH;Nε-Ac-L-Lys-OH;Nε-Acetyllysine
CBNumber
CB3308387
Molecular Formula
C8H16N2O3
Formula Weight
188.22
MOL File
692-04-6.mol
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N-EPSILON-ACETYL-L-LYSINE Property

Melting point:
250 °C (dec.)(lit.)
Boiling point:
323.23°C (rough estimate)
Density 
1.1793 (rough estimate)
refractive index 
1.4500 (estimate)
storage temp. 
-20°C
solubility 
Aqueous Base (Slightly), Water (Slightly)
form 
Powder
pka
2.53±0.24(Predicted)
color 
White
Water Solubility 
Soluble in water (miscible), and 80% acetic acid (50 mg/ml).
Sensitive 
Hygroscopic
InChIKey
DTERQYGMUDWYAZ-ZETCQYMHSA-N
CAS DataBase Reference
692-04-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
24/25-36-26
WGK Germany 
3
HS Code 
29241900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A4021
Product name
Nω-Acetyl-L-lysine
Packaging
1g
Price
$111
Updated
2024/03/01
Sigma-Aldrich
Product number
A4021
Product name
Nω-Acetyl-L-lysine
Packaging
5g
Price
$335
Updated
2024/03/01
TCI Chemical
Product number
A2652
Product name
Nε-Acetyl-L-lysine
Purity
>98.0%(T)
Packaging
1g
Price
$51
Updated
2024/03/01
Alfa Aesar
Product number
J64139
Product name
N(epsilon)-Acetyl-L-lysine, 99%
Packaging
1g
Price
$56.65
Updated
2024/03/01
Alfa Aesar
Product number
J64139
Product name
N(epsilon)-Acetyl-L-lysine, 99%
Packaging
5g
Price
$195
Updated
2024/03/01
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N-EPSILON-ACETYL-L-LYSINE Chemical Properties,Usage,Production

Description

Acetyllysine (or acetylated lysine) is an acetyl-derivative of the amino acid lysine. There are multiple forms of acetyllysine - this article refers to N-ε-acetyl-L-lysine. The other form is N-α-acetyl-Llysine.
In proteins, the acetylation of lysine residues is an important mechanism of epigenetics. It functions by regulating the binding of histones to DNA in nucleosomes and thereby controlling the expression of genes on that DNA. Non-histone proteins are acetylated as well. Unlike the functionally similar methyllysine, acetyllysine does not carry a positive charge on its side chain.
Histone acetyltransferases (HATs) catalyze the addition of acetyl groups from acetyl-CoA onto certain lysine residues of histones and non-histone proteins. Histone deacetylases (HDACs) catalyze the removal of acetyl groups from acetylated lysines.
Acetyllysine can be synthesized from lysine by the selective acetylation of the terminal amine group.

Chemical Properties

white crystalline powder

Uses

N-Epsilon-acetyl-l-lysine is used in the metabolomics study on the combined effect of cocaine and ethanol via liquid chromatography-mass spectrometry metabolomics approach.

Definition

ChEBI: An N6-acyl-L-lysine where the N6-acyl group is specified as acetyl.

Biochem/physiol Actions

Nε-Acetyl-L-lysine (L-AcK) is an R-chain N-acetylated α amino acid used together with other lysine analogues to differentiate and characterized various aminoacylases and regulator 2 (Sir2) enzymes/sirtuins.

N-EPSILON-ACETYL-L-LYSINE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-EPSILON-ACETYL-L-LYSINE Suppliers

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View Lastest Price from N-EPSILON-ACETYL-L-LYSINE manufacturers

Career Henan Chemical Co
Product
N-EPSILON-ACETYL-L-LYSINE 692-04-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20kg
Release date
2018-08-15

692-04-6, N-EPSILON-ACETYL-L-LYSINERelated Search:

Biocytin 5-Hydroxytryptophan (S)-2-amino-3-(4-(2-tert-butoxy-2-oxoethyl)phenyl)propanoic acid H-LYS(ALLOC)-OH H-L-Lys-NEt2.2HCl H-Lys(Boc)-OBzl·HCl H-Lys(Boc)-OH H-L-Pen-OH.HCl.H2O H-L-Tyr-NEt2.HCl L-Phenylalanine, 4-cyclohexyl- FMOC-LYS(PALMITOYL)-OH N-(3-MALEIMIDOPROPIONYL)BIOCYTIN N-EPSILON-ACETYL-L-LYSINE N-ALPHA-FMOC-N-EPSILON-ACETYL-L-LYSINE,FMOC-N-EPSILON-ACETYL-L-LYSINE,N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-EPSILON-ACETYL-L-LYSINE N-6-Trifluoroacetyl-L-lysine Fmoc-N-epsilon-trifluoroacetyl-L-lysine BOC-LYS(TFA)-OH FMOC-LYS(BIOTIN)-OH

  • N-E-ACETYL-L-LYSINE
  • N-EPSILON-ACETYL-L-LYS
  • N-EPSILON-ACETYL-L-LYSINE
  • H-LYS(AC)-OH
  • H-L-LYS(AC)-OH
  • (2S)-6-acetamido-2-amino-hexanoic acid
  • N-epsilon-acetyllysine
  • LYSINE(AC)-OH
  • (2S)-2-amino-6-acetamidohexanoic acid
  • N6-Acetyllysine
  • Nε-Acetyllysine
  • Nε-Ac-L-Lys-OH
  • N-epsilon-Acetyl-L-lysine,99%
  • 6-N-Acetyl-L-lysine-6-N-Acetyl-L-lysine-d8
  • (S)-6-acetaMido-2-aMinohexanoic acid
  • N<sup>ε</sup>-Acetyl-L-lysine
  • epsilon-Acetyl-L-lysine
  • epsilon-N-Acetyllysine
  • NSC 102777
  • omega-N-Acetyl-L-lysine
  • </sup>-Acetyl-<small>L</small>-lysine
  • Nε-Acetyl-L-lysine≥ 99% (HPLC)
  • L-Lysine, N6-acetyl-
  • N-EPSILON-ACETYL-L-LYSINE USP/EP/BP
  • N-epsilon-acetyl-laevo-lysine
  • lys(ac)
  • Lysine impurity 23
  • Lysine Impurity 10
  • Rabbit Anti-Acetylated Lysine antibody
  • Mouse Anti-Acetylated Lysine antibody
  • 692-04-6
  • CH3CONHCH24CHNH2CO2H
  • Amino Acids and Peptides
  • BioChemical
  • Biochemicals and Reagents
  • A - H
  • Modified Amino Acids
  • A - H
  • Amino Acids
  • Modified Amino Acids