1-(3-Chlorophenyl)piperazine hydrochloride

Product Name: 1-(3-Chlorophenyl)piperazine hydrochloride
CAS No.: 65369-76-8
Chemical Name: 1-(3-Chlorophenyl)piperazine hydrochloride
Synonyms: M-CPP;1-(3-ChL;TIMTEC-BB SBB003261;M-CPP HYDROCHLORIDE;Trazodone Impurity 1;LABOTEST-BB LT00159902;TRAZODONE CPP IMPURITY;Aripiprazole Impurity 35;Aripiprazole Impurity 36;Trazodone Chlorophenylpiperazine
CBNumber: CB3325544
Molecular Formula: C10H14Cl2N2
Formula Weight: 233.14
MOL File: 65369-76-8.mol

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1-(3-Chlorophenyl)piperazine hydrochloride Property

Melting point:: 210-214 °C (dec.)(lit.)
Density: 1,193g/cm
refractive index: 1,598-1,600
Flash point:: 9℃
storage temp.: Store at RT
solubility: methanol: soluble
form: Solid
color: Pale brown
Stability:: Hygroscopic
CAS DataBase Reference: 65369-76-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn,T,F
Risk Statements: 36/37/38-22-39/23/24/25-23/24/25-11
Safety Statements: 26-36-24/25-45-36/37-16-7
RIDADR: UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 125180
Product name: 1-(3-Chlorophenyl)piperazine hydrochloride
Purity: 99%
Packaging: 5g
Price: $60.1
Updated: 2025/07/31

Sigma-Aldrich

Product number: C-089
Product name: 1-(3-Chlorophenyl)piperazine hydrochloride solution
Purity: 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
Packaging: 1mL
Price: $118
Updated: 2025/07/31

Sigma-Aldrich

Product number: 125180
Product name: 1-(3-Chlorophenyl)piperazine hydrochloride
Purity: 99%
Packaging: 25g
Price: $166
Updated: 2025/07/31

Frontier Specialty Chemicals

Product number: JK198733
Product name: 1-(3-Chlorophenyl)piperazine hydrochloride
Purity: 98%
Packaging: 5g
Price: $70
Updated: 2021/12/16

AK Scientific

Product number: Z4075
Product name: 1-(3-Chlorophenyl)piperazine hydrochloride
Packaging: 100g
Price: $107
Updated: 2021/12/16

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1-(3-Chlorophenyl)piperazine hydrochloride Chemical Properties,Usage,Production

Chemical Properties

Off-white solid

Uses

Chlorophenyl Piperazine Hydrochloride Salt is a useful intermediate for organic synthesis and other chemical properties. Trazodone impurity.

General Description

1-(3-Chlorophenyl)-piperazine, also known as meta-chlorophenylpiperazine or mCPP, is a designer drug analog of aryl-substituted piperazines. A stimulant, serotonin antagonist and reuptake inhibitor (SARU), mCPP can also be detected as a primary urinary metabolite of the antidepressant drug trazadone. This certified solution standard is suitable for use in piperazine testing methods by LC/MS or GC/MS for clinical toxicology, forensic analysis, or urine drug testing applications.

Biological Activity

5-HT 2C/2B receptor agonist/partial agonist; displays some activity at 5-HT 2A and 5-HT 1 receptors. pEC 50 values are 7.09, 7.2, 6.65, 5.9 and 6.5 for human recombinant 5-HT 2C , 2B and 2A , bovine 5-HT 1A and rat 5-HT 1B receptors respectively. Suppresses locomotor activity in rats in vivo .

1-(3-Chlorophenyl)piperazine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1-(3-Chlorophenyl)piperazine hydrochloride manufacturers

Career Henan Chemical Co

Product: 1-(3-Chlorophenyl)piperazinehydrochloride 65369-76-8
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: kg/T
Release date: 2019-12-18

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65369-76-8

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C10H13ClN2xHCl

C10H13ClN2HClC10H14Cl2N2

C10H13ClN2HCl

5-HT2c serotonin receptor agonist; metabolite of trazodone.

Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

Piperazines

Serotonin receptor

Piperazines

API intermediates