ChemicalBook > CAS DataBase List > 1,4-Benzodioxin-5-carboxamide, 8-amino-7-chloro-N-[(2S)-1,4-diazabicyclo[2.2.2]oct-2-ylmethyl]-2,3-dihydro-

1,4-Benzodioxin-5-carboxamide, 8-amino-7-chloro-N-[(2S)-1,4-diazabicyclo[2.2.2]oct-2-ylmethyl]-2,3-dihydro-

Product Name
1,4-Benzodioxin-5-carboxamide, 8-amino-7-chloro-N-[(2S)-1,4-diazabicyclo[2.2.2]oct-2-ylmethyl]-2,3-dihydro-
CAS No.
186348-68-5
Chemical Name
1,4-Benzodioxin-5-carboxamide, 8-amino-7-chloro-N-[(2S)-1,4-diazabicyclo[2.2.2]oct-2-ylmethyl]-2,3-dihydro-
Synonyms
5-HT3-In-1;5HT3In1,5 HT3 In 1,5-HT-3-In-1;1,4-Benzodioxin-5-carboxamide, 8-amino-7-chloro-N-[(2S)-1,4-diazabicyclo[2.2.2]oct-2-ylmethyl]-2,3-dihydro-
CBNumber
CB33339540
Molecular Formula
C16H21ClN4O3
Formula Weight
352.82
MOL File
186348-68-5.mol
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1,4-Benzodioxin-5-carboxamide, 8-amino-7-chloro-N-[(2S)-1,4-diazabicyclo[2.2.2]oct-2-ylmethyl]-2,3-dihydro- Property

Boiling point:
482.3±45.0 °C(Predicted)
Density 
1.46±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
13.27±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

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1,4-Benzodioxin-5-carboxamide, 8-amino-7-chloro-N-[(2S)-1,4-diazabicyclo[2.2.2]oct-2-ylmethyl]-2,3-dihydro- Chemical Properties,Usage,Production

Uses

5-HT3-In-1 is extracted from patent EP0748807A1, compound example 8. It shows 5-HT3 inhibition activity.

IC 50

5-HT3 Receptor

References

[1] Jegham S, et al. Derivatives of N-(1,4-diazabicyclo(2.2.2)-oct-2-yl)methyl benzamide, their preparation and their therapeutical use. EP0748807A1.

1,4-Benzodioxin-5-carboxamide, 8-amino-7-chloro-N-[(2S)-1,4-diazabicyclo[2.2.2]oct-2-ylmethyl]-2,3-dihydro- Preparation Products And Raw materials

Raw materials

Preparation Products

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1,4-Benzodioxin-5-carboxamide, 8-amino-7-chloro-N-[(2S)-1,4-diazabicyclo[2.2.2]oct-2-ylmethyl]-2,3-dihydro- Suppliers

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186348-68-5, 1,4-Benzodioxin-5-carboxamide, 8-amino-7-chloro-N-[(2S)-1,4-diazabicyclo[2.2.2]oct-2-ylmethyl]-2,3-dihydro-Related Search:


  • 5-HT3-In-1
  • 1,4-Benzodioxin-5-carboxamide, 8-amino-7-chloro-N-[(2S)-1,4-diazabicyclo[2.2.2]oct-2-ylmethyl]-2,3-dihydro-
  • 5HT3In1,5 HT3 In 1,5-HT-3-In-1
  • 186348-68-5