3-ETHYNYL-BENZOIC ACID
- Product Name
- 3-ETHYNYL-BENZOIC ACID
- CAS No.
- 10601-99-7
- Chemical Name
- 3-ETHYNYL-BENZOIC ACID
- Synonyms
- 3-ETHYNYL-BENZOIC ACID;3-Eethynylbenzoic acid;Benzoic acid, 3-ethynyl-;3-Ethynylbenzoic acid 95%;Benzoic acid, 3-ethynyl- (9CI);3-Ethynylbenzoic acid - [E50962];3-ethynylbenzoic acid(SALTDATA: FREE)
- CBNumber
- CB3374577
- Molecular Formula
- C9H6O2
- Formula Weight
- 146.14
- MOL File
- 10601-99-7.mol
3-ETHYNYL-BENZOIC ACID Property
- Melting point:
- 164-171°C
- Boiling point:
- 300.2±25.0 °C(Predicted)
- Density
- 1.23±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 3.99±0.10(Predicted)
- form
- powder
- Appearance
- White to off-white Solid
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-36-43
- Safety Statements
- 26-36/37/39
- WGK Germany
- nwg
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H317May cause an allergic skin reaction
H319Causes serious eye irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 724645
- Product name
- 3-Ethynylbenzoic acid
- Purity
- 95%
- Packaging
- 1g
- Price
- $128
- Updated
- 2025/07/31
- Product number
- E937168
- Product name
- 3-Ethynylbenzoic acid
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 5335AH
- Product name
- 3-Ethynylbenzoic acid
- Packaging
- 1g
- Price
- $83
- Updated
- 2021/12/16
- Product number
- AS85698
- Product name
- 3-Ethynyl-benzoic acid
- Purity
- 97+%
- Packaging
- 1g
- Price
- $88
- Updated
- 2021/12/16
- Product number
- E50962
- Product name
- 3-Ethynylbenzoic acid
- Purity
- 97%
- Packaging
- 250mg
- Price
- $20
- Updated
- 2021/12/16
3-ETHYNYL-BENZOIC ACID Chemical Properties,Usage,Production
Synthesis
77123-59-2
10601-99-7
Step 2: Methyl 3-((trimethylsilyl)ethynyl)benzoate (105) (2.42 g) was dissolved in methanol (30 mL), and 2N aqueous sodium hydroxide solution (10.4 mL) was slowly added under cooling in an ice bath, and the reaction was stirred at room temperature for 7 hours. After completion of the reaction, the pH of the reaction mixture was adjusted to 3~4 with 2N hydrochloric acid, followed by concentration under reduced pressure. Water (100 mL) was added to the residue and extracted with ethyl acetate (100 mL). The organic layer was washed with saturated brine (100 mL), dried over anhydrous sodium sulfate and filtered. The filtrate was concentrated under reduced pressure to give 3-ethynylbenzoic acid (106) as a white solid (1.50 g, 99% yield).
References
[1] Journal of Medicinal Chemistry, 2012, vol. 55, # 22, p. 9562 - 9575
[2] Patent: JP5725475, 2015, B2. Location in patent: Paragraph 0028; 0031
[3] Patent: WO2014/168824, 2014, A1. Location in patent: Page/Page column 19
3-ETHYNYL-BENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-ETHYNYL-BENZOIC ACID manufacturers
- Product
- 3-ETHYNYL-BENZOIC ACID 10601-99-7
- Price
- US $6.60/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg-1000kg
- Release date
- 2019-12-26