ChemicalBook > CAS DataBase List > CALCISEPTINE
CALCISEPTINE
- Product Name
- CALCISEPTINE
- CAS No.
- 178805-91-9
- Chemical Name
- CALCISEPTINE
- Synonyms
- CAS;CSE1;XPO2;Exportin-2;CALCISEPTINE;Calciseptine (Recombinant);CSE1 chromosome segregation 1-like;chromosome segregation 1-like protein;CALCISEPTINE, DENDROASPIS POLYLEPIS POLYLEPIS;Anti-CSE1L, N-Terminal antibody produced in rabbit
- CBNumber
- CB3472613
- Formula Weight
- 0
- MOL File
- Mol file
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CALCISEPTINE Property
- storage temp.
- -20°C
- Sequence
- Arg-Ile-Cys-Tyr-Ile-His-Lys-Ala-Ser-Leu-Pro-Arg-Ala-Thr-Lys-Thr-Cys-Val-Glu-Asn-Thr-Cys-Tyr-Lys-Met-Phe-Ile-Arg-Thr-Gln-Arg-Glu-Tyr-Ile-Ser-Glu-Arg-Gly-Cys-Gly-Cys-Pro-Thr-Ala-Met-Trp-Pro-Tyr-Gln-Thr-Glu-Cys-Cys-Lys-Gly-Asp-Arg-Cys-Asn-Lys (Disulfide bridge:Cys3-Cys22;Cys17-Cys39;Cys41-Cys52; Cys53-Cys58)
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CALCISEPTINE Chemical Properties,Usage,Production
Uses
Calciseptine, a natural?neurotoxin?isolated from the black mamba Dendroaspis p. polylepis venom. Calciseptine consists of 60 amino acids with four disulfide bonds. Calciseptine specifically blocks L-type?calcium channel[1].
IC 50
L-type calcium channel: 15 nM (IC50)
References
[1] H Schweitz, et al. Calcicludine, a venom peptide of the Kunitz-type protease inhibitor family, is a potent blocker of high-threshold Ca2+ channels with a high affinity for L-type channels in cerebellar granule neurons. Proc Natl Acad Sci U S A. 1994 Feb 1; 91(3): 878–882. DOI:10.1073/pnas.91.3.878
CALCISEPTINE Preparation Products And Raw materials
Raw materials
Preparation Products
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CALCISEPTINE Suppliers
- Tel
- --
- Fax
- --
- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71
178805-91-9, CALCISEPTINERelated Search:
Toxins and Analogues
ODK2
KURTOXIN
ODK2 analogues
μ-conotoxin GlllA
SHK TOXIN
OMEGA-AGATOXIN IVA
SSD609
HUWENTOXIN IV
mu-conotoxin
PLTX-ll
ω-conotoxin MVllA
Dendrotoxin-l
ω-agatoxin IVB
SNX-482
Mambalgin-3
a-conotoxin lml
CALCISEPTINE,CALCISEPTINE, DENDROASPIS POLYLEPIS POLYLEPIS