ChemicalBook > CAS DataBase List > BigLEN (mouse)
BigLEN (mouse)
- Product Name
- BigLEN (mouse)
- CAS No.
- 501036-69-7
- Chemical Name
- BigLEN (mouse)
- Synonyms
- BigLEN (mouse);GPR171 agonist TFA;L-Proline, L-leucyl-L-α-glutamyl-L-asparaginyl-L-prolyl-L-seryl-L-prolyl-L-glutaminyl-L-alanyl-L-prolyl-L-alanyl-L-arginyl-L-arginyl-L-leucyl-L-leucyl-L-prolyl-
- CBNumber
- CB34902703
- Molecular Formula
- C78H130N24O22
- Formula Weight
- 1756.04
- MOL File
- 501036-69-7.mol
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BigLEN (mouse) Property
- Density
- 1.51±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 3.44±0.20(Predicted)
- form
- Solid
- color
- White to off-white
- Water Solubility
- Soluble to 2 mg/ml in water
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N-Bromosuccinimide Price
Tocris
- Product number
- 6304
- Product name
- BigLEN(mouse)
- Packaging
- 1
- Price
- $195
- Updated
- 2021/12/16
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BigLEN (mouse) Chemical Properties,Usage,Production
Uses
BigLEN(mouse) is a potent and selective agonist of orphan G protein-coupled receptor 171 (GPR171), with a Kd of ~0.5 nM. BigLEN(mouse) can be used to regulate responses associated with food intake and metabolism[1][2].
storage
Store at -20°C
References
[1] Gomes I, et, al. GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16211-6. DOI:10.1073/pnas.1312938110
[2] Mack SM, et, al. Neuropeptide PEN and Its Receptor GPR83: Distribution, Signaling, and Regulation. ACS Chem Neurosci. 2019 Apr 17;10(4):1884-1891. DOI:10.1021/acschemneuro.8b00559
BigLEN (mouse) Preparation Products And Raw materials
Raw materials
Preparation Products
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