VP3.15 Dihydrobromide

Product Name: VP3.15 Dihydrobromide
CAS No.: 1281681-33-1
Chemical Name: VP3.15 Dihydrobromide
Synonyms: VP3.15 Dihydrobromide;VP3.15 dihydrobromide, 10 mM in DMSO;N-(2-Morpholinoethyl)-2,3-diphenyl-1,2,4-thiadiazol-5(2H)-imine dihydrobromide;Glycogen synthase kinase-3,VP3.15 dihydrobromide,inhibit,Inhibitor,VP-3.15 dihydrobromide,Glycogen synthase kinase 3,GSK-3,Phosphodiesterase (PDE)
CBNumber: CB35441036
Molecular Formula: C20H23BrN4OS
Formula Weight: 447.4
MOL File: 1281681-33-1.mol

More

Less

VP3.15 Dihydrobromide Property

storage temp.: Store at -20°C
solubility: dmso:62.5(Max Conc. mg/mL);118.3(Max Conc. mM)
form: Solid
color: Light yellow to yellow

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

ChemScene

Product number: CS-0101863
Product name: VP3.15(dihydrobromide)
Purity: 98.22%
Packaging: 5mg
Price: $150
Updated: 2021/12/16

ChemScene

Product number: CS-0101863
Product name: VP3.15(dihydrobromide)
Purity: 98.22%
Packaging: 10mg
Price: $250
Updated: 2021/12/16

ChemScene

Product number: CS-0101863
Product name: VP3.15(dihydrobromide)
Purity: 98.22%
Packaging: 50mg
Price: $900
Updated: 2021/12/16

ChemScene

Product number: CS-0101863
Product name: VP3.15(dihydrobromide)
Purity: 98.22%
Packaging: 100mg
Price: $1550
Updated: 2021/12/16

DC Chemicals

Product number: 027577
Product name: VP3.15dihydrobromide
Packaging: 003
Price: $2200
Updated: 2021/12/16

More

Less

VP3.15 Dihydrobromide Chemical Properties,Usage,Production

Description

VP3.15 Dihydrobromide is a novel dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor.

Uses

VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. VP3.15 dihydrobromide has neuroprotective and neuroreparative activities, thus as potential combined anti-inflammatory and pro-remyelinating therapies for multiple sclerosis (MS)[1].

target

VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively.

References

[1] Medina-Rodríguez EM, et al. Promoting in vivo remyelination with small molecules: a neuroreparative pharmacological treatment for Multiple Sclerosis. Sci Rep. 2017 Mar 3;7:43545. DOI:10.1038/srep43545

VP3.15 Dihydrobromide Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

VP3.15 Dihydrobromide Suppliers

China 25 United States 3 Global 28

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6003
Advantage: 61

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7778
Advantage: 56

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4757
Advantage: 55

Shanghai Beckham Medical Technology Co., Ltd

Tel: 13816613772
Fax: QQ: 12922499
Email: huahero21@sina.com
Country: China
ProdList: 2390
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8000
Advantage: 62

Shanghai Rechem science Co., Ltd.

Tel: 021-31433387 15618786686
Fax: QQ:1369748377
Email: sales@rechemscience.com
Country: China
ProdList: 2988
Advantage: 58

Shanghai Bank Pharma Limited

Tel: 021-2221346380 021-54220652 17701603001
Fax: QQ:2221346380
Email: bankpharma@163.com
Country: China
ProdList: 423
Advantage: 58

HANGZHOU CLAP TECHNOLOGY CO.,LTD

Tel: 86-571-88216897,88216896 13588875226
Fax: 86-571-88216895
Email: sales@hzclap.com
Country: CHINA
ProdList: 6312
Advantage: 58

Shanghai hongqu biomedical technology co. LTD

Tel: 88888888888
Email: hongquchem@qq.com
Country: China
ProdList: 5132
Advantage: 58

Zhengzhou convergence chemical co., LTD

Tel: 0371-0371-55153829 18003835034
Email: 2853979819@qq.com
Country: China
ProdList: 9998
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Nantong QuanYi Biotechnology Co., Ltd

Tel: 0513-66337626 18051384581
Email: sales@chemhifuture.com
Country: China
ProdList: 5929
Advantage: 58

RD International Technology Co., Limited

Tel: 18024082417
Email: market@ubiochem.com
Country: China
ProdList: 9835
Advantage: 58

Shanghai Fine Biotech Co.，Ltd

Tel: 18221172427
Email: sale@fine-biotech.com
Country: China
ProdList: 2772
Advantage: 58

Sangon Biotech (Shanghai) Co.,Ltd.

Tel: 400-821-026
Email: Sales@sangon.com
Country: China
ProdList: 6710
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

Adooq Bioscience LLC

Tel: 400-025-6535
Email: sales@adooq.cn
Country: China
ProdList: 6215
Advantage: 58

ATK CHEMICAL COMPANY LIMITED

Tel: +undefined-21-51877795
Fax: +86 21 5161 9052/ 5187 7796
Email: ivan@atkchemical.com
Country: China
ProdList: 33024
Advantage: 60

Tianjin Baibei Biotechnology Co., Ltd.

Tel: 15302170631
Country: CHINA
ProdList: 166
Advantage: 58

Shenzhen Zuoke Biotechnology Co., Ltd.

Tel: 13532174601
Country: CHINA
ProdList: 109
Advantage: 58

Absin Bioscience Inc.

Tel: --
Fax: --
Email: chenjw@absin.cn
Country: CHINA
ProdList: 6208
Advantage: 58

Proteintech China

Tel: --
Fax: --
Email: Proteintech-CN@ptglab.com
Country: CHINA
ProdList: 6290
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6650
Advantage: 58

1281681-33-1, VP3.15 DihydrobromideRelated Search:

VP3.15 Dihydrobromide

Glycogen synthase kinase-3,VP3.15 dihydrobromide,inhibit,Inhibitor,VP-3.15 dihydrobromide,Glycogen synthase kinase 3,GSK-3,Phosphodiesterase (PDE)

N-(2-Morpholinoethyl)-2,3-diphenyl-1,2,4-thiadiazol-5(2H)-imine dihydrobromide

VP3.15 dihydrobromide, 10 mM in DMSO

1281681-33-1