LEUCOPTERIN Property

Melting point:

300 °C

Boiling point:

331.78°C (rough estimate)

Density 

1.5875 (rough estimate)

refractive index 

1.8500 (estimate)

solubility 

Aqueous Base (Slightly)

form 

Solid

pka

6.74±0.20(Predicted)

color 

Pale Beige to Beige

Water Solubility 

1.333mg/L(22.5 ºC)

Hazard and Precautionary Statements (GHS)

LEUCOPTERIN Chemical Properties,Usage,Production

Uses

Leucopterin (cas# 492-11-5) is a useful research chemical. It is used in the methods of drug screening to identify compounds for treatment of protein trafficking diseases.

Definition

ChEBI: Leucopterin (enol form) is a member of the class of pteridines that is pteridine substituted by an amino group at position 2 and hydroxy groups at positions 4, 6 and 7. It has a role as a biological pigment. It is a member of pteridines, a heteroaryl hydroxy compound and a triol. It is a tautomer of a leucopterin (keto form).

Purification Methods

Leucopterin is purified by dissolving it in aqueous NaOH, stirring with charcoal, filtering and precipitating by adding aqueous HCl, then drying at 100o in a vacuum. It separates with 0.5 mole of H2O. Its solubility in H2O is 1g/750 litres [Albert et al. J Chem Soc 4219 1952, Albert & Wood J Appl Chem (London) 2 591 1952, Pfleiderer Chem Ber 90 2631 1957]. [Beilstein 26 III/IV 4017.]