ChemicalBook > CAS DataBase List > 2-AMINO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER

2-AMINO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER

Product Name
2-AMINO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER
CAS No.
57401-76-0
Chemical Name
2-AMINO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER
Synonyms
EOS-60351;NSC 165511;5-Carbethoxy-2-pyriMidinaMine;ETHYL 2-AMINO-5-PYRIMIDINECARBOXYLATE;2-Amino-5-pyrimidinecarboxylic acid ethyl ester;2-AMINO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER;5-PyriMidinecarboxylic acid, 2-aMino-, ethyl ester;2-AMINO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER ISO 9001：2015 REACH
CBNumber
CB3721360
Molecular Formula
C7H9N3O2
Formula Weight
167.17
MOL File
57401-76-0.mol
More
Less

2-AMINO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER Property

Melting point:
147-149℃
Boiling point:
349℃
Density 
1.261
Flash point:
165℃
storage temp. 
2-8°C(protect from light)
pka
1.94±0.10(Predicted)
Appearance
White to light yellow Solid
More
Less

Safety

HS Code 
2933599590
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
A617145
Product name
2-Amino-pyrimidine-5-carboxylicAcidEthylEster
Packaging
500mg
Price
$145
Updated
2021/12/16
Usbiological
Product number
415417
Product name
2-Amino-pyrimidine-5-carboxylic Acid Ethyl Ester
Packaging
100mg
Price
$312
Updated
2021/12/16
Apolloscientific
Product number
OR912994
Product name
2-Amino-pyrimidine-5-carboxylicacidethylester
Purity
95%
Packaging
1g
Price
$140
Updated
2021/12/16
Matrix Scientific
Product number
076316
Product name
Ethyl 2-aminopyrimidine-5-carboxylate
Purity
95+%
Packaging
1g
Price
$221
Updated
2021/12/16
Apolloscientific
Product number
OR912994
Product name
2-Amino-pyrimidine-5-carboxylicacidethylester
Purity
95%
Packaging
5g
Price
$460
Updated
2021/12/16
More
Less

2-AMINO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER Chemical Properties,Usage,Production

Uses

2-Amino-pyrimidine-5-carboxylic Acid Ethyl Ester is a reagent used in the synthesis of retinoidal pyrimidinecarboxylic acids.

Synthesis

148550-51-0

57401-76-0

The general procedure for the synthesis of ethyl 2-aminopyrimidine-5-carboxylate from ethyl 2-methylsulfonyl-5-pyrimidinecarboxylate was as follows: ethyl 2-(methylsulfonyl)pyrimidine-5-carboxylate (2.15 g, 9.34 mmol) was dissolved in acetonitrile (11.7 mL) and stirred at room temperature. Subsequently, 32% aqueous ammonium hydroxide solution (11.36 mL, 93 mmol) was added slowly and dropwise. The reaction mixture transformed into a white suspension within seconds. The acetonitrile was removed by rotary evaporator and the remaining aqueous phase suspension was filtered through a Brinell funnel. The resulting solid was washed with distilled water (20 mL) and dried to give ethyl 2-aminopyrimidine-5-carboxylate as a white solid (1.192 g, 7.13 mmol, 76% yield, MS/ESI+ 168.1 [MH]+).

References

[1] Patent: US2013/79313, 2013, A1. Location in patent: Paragraph 1024
[2] Patent: WO2013/45280, 2013, A1. Location in patent: Page/Page column 276

2-AMINO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials

Sodium hydride Ethyl formate Propanoicacid,2-formyl-3-oxo-,ethylester Sodium Guanidine hydrochloride Ethyl acetate Ethyl 3,3-Diethoxypropionate

Preparation Products

More
Less

2-AMINO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER Suppliers

China 96 Germany 1 India 1 United Kingdom 1 United States 7 Global 106
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
More
Less

View Lastest Price from 2-AMINO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER manufacturers

Dideu Industries Group Limited
Product
2-AMINO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER 57401-76-0
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-12-13
Career Henan Chemical Co
Product
2-AMINO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER 57401-76-0
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2019-12-26

57401-76-0, 2-AMINO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTERRelated Search:

Ethyl 2-amino-1,3-thiazole-4-carboxylate 2-Aminotoluene-5-sulfonic acid 6-Aminopyridine-2-carboxylic acid 2-Aminopyrimidine-5-carboxylic acid 2-AMINO-5-CARBOETHOXY-4-HYDROXYPYRIMIDINE ETHYL 2-AMINO-4-METHYLPYRIMIDINE-5-CARBOXYLATE ETHYL 2-AMINO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE ETHYL 2-AMINO-4-PROPYLPYRIMIDINE-5-CARBOXYLATE 2-AMINO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER ETHYL 2-MORPHOLINO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE 5-(4-CHLOROBENZYLOXYCARBONYL)-4-(TRIFLUOROMETHYL)PYRIMIDIN-2-YL HYDRAZINE ETHYL 4-HYDROXY-2-(PIPERIDIN-1-YL)PYRIMIDINE-5-CARBOXYLATE ETHYL 4-HYDROXY-2-MORPHOLINOPYRIMIDINE-5-CARBOXYLATE ETHYL 2-(2-[3-(CHLOROMETHYL)BENZOYL]HYDRAZINO)-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE BENZYL 2-HYDRAZINO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE ETHYL 2,4-DIAMINO-6-METHYLPYRIMIDINE-5-CARBOXYLATE ETHYL 2-HYDRAZINO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE 4-CHLOROBENZYL 2-[2-(2-CHLOROACETYL)HYDRAZINO]-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE

  • ETHYL 2-AMINO-5-PYRIMIDINECARBOXYLATE
  • 2-AMINO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER
  • 5-Carbethoxy-2-pyriMidinaMine
  • 5-PyriMidinecarboxylic acid, 2-aMino-, ethyl ester
  • 2-Amino-5-pyrimidinecarboxylic acid ethyl ester
  • NSC 165511
  • EOS-60351
  • 2-AMINO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER ISO 9001：2015 REACH
  • 57401-76-0
  • Heterocycle-Pyrimidine series
  • pharmacetical
  • API intermediates