3-Aminopropionitrile

Product Name: 3-Aminopropionitrile
CAS No.: 151-18-8
Chemical Name: 3-Aminopropionitrile
Synonyms: 3-AMINOPROPANENITRILE;BAPN;β-aminopropionitrile;beta-Aminopropionitrile;AMINOPROPIONITRILE;2-CYANOETHYLAMINE;beta-Alaninenitrile;B-AMINOPROPIONITRILE;BETA-AMINOPROPIONONITRILE;e (stabiL
CBNumber: CB3853135
Molecular Formula: C3H6N2
Formula Weight: 70.09
MOL File: 151-18-8.mol

More

Less

3-Aminopropionitrile Property

Melting point:: <25 °C
Boiling point:: 185 °C
Density: 0.9584
refractive index: 1.4365-1.4395
Flash point:: 79-81°C/16mm
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
solubility: Chloroform, Methanol
form: Liquid
pka: 7.80(at 20℃)
color: Clear colorless to yellow
Water Solubility: Soluble in water.
Sensitive: Air & Moisture Sensitive
Merck: 14,469
BRN: 1698848
InChIKey: AGSPXMVUFBBBMO-UHFFFAOYSA-N
CAS DataBase Reference: 151-18-8(CAS DataBase Reference)
EPA Substance Registry System: Propanenitrile, 3-amino- (151-18-8)

More

Less

Safety

Hazard Codes: Xn,C
Risk Statements: 20/21/22-34-22-63
Safety Statements: 36/37-45-36/37/39-26
RIDADR: 3276
RTECS: UG0350000
TSCA: Yes
HazardClass: 8
PackingGroup: III
HS Code: 29269090
Hazardous Substances Data: 151-18-8(Hazardous Substances Data)

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H227Combustible liquid

H301Toxic if swalloed

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CDS007521
Product name: 3-amino-propionitrile
Purity: AldrichCPR
Packaging: 1G
Price: $201
Updated: 2023/06/20

TCI Chemical

Product number: A0408
Product name: 3-Aminopropionitrile (stabilized with K2CO3)
Purity: >98.0%(GC)(T)
Packaging: 25mL
Price: $123
Updated: 2024/03/01

Alfa Aesar

Product number: A13043
Product name: 3-Aminopropionitrile, 98%, stab. with potassium carbonate
Packaging: 1g
Price: $37.65
Updated: 2024/03/01

Alfa Aesar

Product number: A13043
Product name: 3-Aminopropionitrile, 98%, stab. with potassium carbonate
Packaging: 5g
Price: $102.65
Updated: 2024/03/01

Alfa Aesar

Product number: A13043
Product name: 3-Aminopropionitrile, 98%, stab. with potassium carbonate
Packaging: 25g
Price: $353.65
Updated: 2024/03/01

More

Less

3-Aminopropionitrile Chemical Properties,Usage,Production

Chemical Properties

clear colourless to yellow liquid. 3-Aminopropionitrile, [151-18-8], 3-aminopropanenitrile, b-aminopropionitrile, H2N – CH2 – CH2CN, Mr 70.09, bp 185℃ (101.3 kPa), n20D 1.4396, is a colorless liquid which tends to slowly polymerize if stored in the presence of air. 3-Aminopropionitrile is prepared by the reaction of acrylonitrile with ammonia and is mainly used as an intermediate in the manufacture of b-alanine and pantothenic acid [48].

Uses

Production of β-alanine and pantothenic acid.

Uses

3-Aminopropionitrile is used for organic synthesis and as pharmaceutical intermediates. As an intermediate used in the manufacture of beta-alanine and pantothenic acid.

Definition

ChEBI: 3-Aminopropionitrile is an aminopropionitrile carrying an amino group at the beta-position. It has a role as a plant metabolite, an antineoplastic agent, an antirheumatic drug and a collagen cross-linking inhibitor. It is a conjugate base of a beta-ammoniopropionitrile.

Safety Profile

Moderately toxic by intraperitoneal route. An experimental teratogen. Other experimental reproductive effects. Mutation data reported. Nitriles usually have cyanide-like effects. See also CYANIDE. Easily oxidized and unstable. A storage hazard; it polymerizes to an explosive yellow solid. When heated to decomposition it emits toxic fumes of CNand NO,. For fire and explosion hazards see CYANIDE.

Metabolism

3-Aminopropionitrile is the compound present in some Lathyms species (Leguminosae), especially sweet-pea seeds (L. odoratus), causing osteolathyrism in man and animals. Although 3-aminopropionitrile is generally present in the fresh plant as the gama-glutamyl derivative, only the free amine is an effective lathyrogen.
Osteolathyrogens cause skeletal deformations due to interference with the cross-linking between polypeptide chains in the connective tissue components, elastin and collagen. This interference is partly due to inhibition of the synthesis of desmosine and isodesmosine, amino acids which effect the cross-linking in elastin. Cross-linking interference of collagen can be prevented in chicks by feed- ing excess calcium.
It is possible that 3-aminopropionitrile is adegradation product of 3-cyano-alanine, although in many plants the latter compound is converted to asparagine and it has not been detected in Lathyms species.

References

[1] CHAO HAN . Nitrilase-catalyzed hydrolysis of 3-aminopropionitrile at high concentration with a tandem reaction strategy for shifting the reaction to β-alanine formation[J]. Journal of Molecular Catalysis B-enzymatic, 2015, 115: Pages 113-118. DOI:10.1016/j.molcatb.2015.02.007.
[2] C. RICHARD . Rotational spectrum of 3-aminopropionitrile and searches for it in Sagittarius B2(N)[J]. Journal of Molecular Spectroscopy, 2018, 345: Pages 51-59. DOI:10.1016/j.jms.2017.12.003.
[3] MSIEDEEN A A. Conformational Stability of 3-aminopropionitrile: DFT and Ab initio Calculations.[J]. Acta Chimica Slovenica, 2024, 71 2: 244-255. DOI:10.17344/acsi.2023.8486.
[4] A.L.G. ALVES PHD1. Effects of beta-aminopropionitrile fumarate and exercise on equine tendon healing: Gross and histological aspects[J]. Journal of Equine Veterinary Science, 2001, 21 7: Pages 335-340. DOI:10.1016/S0737-0806(01)70076-7.

3-Aminopropionitrile Preparation Products And Raw materials

Raw materials

Ammonium hydroxide tert-Butanol Diphenylamine Acrylonitrile Ammonia

Preparation Products

β-Alanine 1,2-Dimethyl-1,4,5,6-tetrahydropyrimidine Alfuzosin hydrochloride

More

Less

3-Aminopropionitrile Suppliers

Americas 1 Belgium 3 China 139 Europe 1 France 2 Germany 6 India 8 Japan 4 The Netherlands 1 Ukraine 1 United Kingdom 9 United States 34 Global 209

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

Cato Research Chemicals Inc.

Tel: 020-81215950 4000-868-328
Email: customer@uwalab.com
Country: United States
ProdList: 10404
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38631
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

Alfa Chemistry

Tel
Email: info@alfa-chemistry.com
Country: United States
ProdList: 2344
Advantage: 58

Aston Chemical

Tel: 13000000000
Email: sales@astonchem.com
Country: United States
ProdList: 1634
Advantage: 58

Alichem Inc.

Tel: --
Fax: --
Email: sales@alichem.com
Country: United States
ProdList: 6167
Advantage: 58

2A Biotech USA

Tel: --
Fax: --
Email: info@2abiotech.com
Country: United States
ProdList: 1785
Advantage: 58

TCI America, Inc. (Tokyo Chemical Industry Co., Ltd.)

Tel: --
Fax: --
Email: .Crew@tcichemicals.com
Country: United States
ProdList: 3164
Advantage: 58

Aozeal Certified Standards (AOCS), Inc.

Tel: --
Fax: --
Email: info@aozeal.com
Country: United States
ProdList: 504
Advantage: 58

Fluorochem Ltd.

Tel: --
Fax: --
Email: enquiries@fluorochem.co.uk
Country: United States
ProdList: 4583
Advantage: 58

Fine Chem Trading LTD

Tel: --
Fax: --
Email: chemfinder@chemfinder.co.uk
Country: United States
ProdList: 1609
Advantage: 64

VWR International, LLC.

Tel: --
Fax: --
Email: @sargentwelch.com
Country: United States
ProdList: 6262
Advantage: 58

Oakwood Products, Inc.

Tel: --
Fax: --
Email: sales@oakwoodchemical.com
Country: United States
ProdList: 6193
Advantage: 74

Advance Scientific & Chemical

Tel: --
Fax: --
Email: sales@advance-scientific.com
Country: United States
ProdList: 6419
Advantage: 71

Spectrum Chemical Mfg. Corp.

Tel: --
Fax: --
Email: marketing@spectrumchemical.com
Country: United States
ProdList: 3113
Advantage: 60

MedChemExpress

Tel: --
Fax: --
Email: sales@medchemexpress.com
Country: United States
ProdList: 6398
Advantage: 58

Combi-Blocks Inc.

Tel: --
Fax: --
Email: sales@combi-blocks.com
Country: United States
ProdList: 6618
Advantage: 69

TCI America

Tel: --
Fax: --
Email: sales@tciamerica.com
Country: United States
ProdList: 6909
Advantage: 75

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

Reagent World

Tel: --
Fax: --
Email: Sales@ReagentWorld.com
Country: United States
ProdList: 1637
Advantage: 50

ARVI Fine Organic Chemicals Co., Ltd.

Tel: --
Fax: --
Email: vbaden2@yahoo.com
Country: United States
ProdList: 249
Advantage: 50

Waterstone Technology, LLC

Tel: --
Fax: --
Email: sales@waterstonetech.com
Country: United States
ProdList: 6786
Advantage: 30

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

Beta Pharma, Inc.

Tel: --
Fax: --
Email: sales@betapharma.com
Country: United States
ProdList: 6226
Advantage: 60

Pfaltz & Bauer, Inc.

Tel: --
Fax: --
Email: sales@pfaltzandbauer.com
Country: United States
ProdList: 6828
Advantage: 72

Narchem Corporation

Tel: --
Fax: --
Email: sales@narchem.com
Country: United States
ProdList: 2813
Advantage: 60

HONEST JOY HOLDINGS LIMITED

Tel: --
Fax: --
Email: sales@honestjoy.cn
Country: United States
ProdList: 6675
Advantage: 54

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

City Chemical LLC

Tel: --
Fax: --
Email: sales@citychemical.com
Country: United States
ProdList: 6708
Advantage: 72

MP Biomedicals, Inc.

Tel: --
Fax: --
Country: United States
ProdList: 6561
Advantage: 81

City Chemicals Corporation

Tel: --
Fax: --
Country: United States
ProdList: 6460
Advantage: 72

Frinton Laboratories, Inc.

Tel: --
Fax: --
Email: sales@frinton.com
Country: United States
ProdList: 1459
Advantage: 61

Alfa Aesar

Tel: --
Fax: --
Email: tech@alfa.com
Country: United States
ProdList: 6814
Advantage: 81

More

Less

View Lastest Price from 3-Aminopropionitrile manufacturers

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD

Product: 3-Aminopropionitrile 151-18-8
Price: US $990.00-800.00/ton
Min. Order: 1ton
Purity: 99%
Supply Ability: 5000
Release date: 2024-08-19

Hebei Chuanghai Biotechnology Co,.LTD

Product: 3-Aminopropionitrile 151-18-8
Price: US $5.00-2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-08-23

Shaanxi Dideu Medichem Co. Ltd

Product: 3-Aminopropionitrile 151-18-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 1000KG
Release date: 2024-07-16

151-18-8, 3-AminopropionitrileRelated Search:

2,4-DICYANO-3-METHYLGLUTARAMIDE N-Methyl-beta-aminopropionitrile Cyanoacetylurea N-CYANOACETYLURETHANE 1-CYANOACETYLPIPERIDINE Disperse Orange 25 3-Anilinopropionitrile 2-Cyanothioacetamide 3-(BENZYLAMINO)PROPIONITRILE 2-Cyanoacetamide 3,3'-IMINODIPROPIONITRILE Dimethylaminopropionitrile 3-Cyano-6-methyl-2(1H)-pyridinone 2-AMINO-1-PROPENE-1,1,3-TRICARBONITRILE Cyanoacetohydrazide 3-(4-MORPHOLINO)PROPIONITRILE N-(2-CYANOETHYL)PYRROLE Disperse Orange 31

3-AMINOPROPIONITRILE , STABILIZED WITH POTASSIUM CARBONATE

3-AMINOPROPIONITRILE (BETA-) 98+%

3-AMINOPROPIONITRILE, 98%, STAB. WITH POTASSIUM CARBONATE

3-Aminopropionitrile, 98%, stabilized

β-Aminopropanenitrile

B-AMINOPROPIONITRILE

BETA-AMINOPROPIONONITRILE

BETA-AMINOETHYL CYANIDE

3-Aminopropionitrile, stabilized, 98%

3-Aminopropiononitril

3-Aminopropionitrile ,98%

3-AMinopropionitrile, stabilized, 98% 5GR

3-Aminopropionitrile (stabilized with K2CO3)

(stabilized with K2CO3)

3-AMinopropionitrile&nbsp

N-(2-CYANOETHYL)AMINE

BAPN

beta-Alaminenitrile

beta-Alaninenitrile

beta-Aminopropionitrile

beta-Cyanoethylamine

Propanenitrile, 3-amino-

Propionitrile, 3-amino-

3-AMINOPROPANENITRILE

3-AMINOPROPIONITRILE

3-AMINOPROPIONONITRILE

AMINOPROPIONITRILE

β-Aminopropionitrite

2-CYANOETHYLAMINE

3-AminopropionitriL

3-Aminopropionitrile (stabilized with K2CO3)&gt

e (stabiL

ized with K2CO3)

β-aminopropionitrile

3-Aminopropionitrile D4

βAminopropionitrile,BAPN,insulin,Monoamine Oxidase,β Aminopropionitrile,inhibit,GLUT4,lysyl oxidase,Inhibitor,β-Aminopropionitrile,SiHa,obesity,cervical carcinoma cells,Endogenous Metabolite,thoracic aortic dissection,MAO,HeLa

β-Aminopropionitrile(BAPN)

3-Aminopropionitrile (stab. with 0.1% potassium carbonate)

151-18-8

H2NCH2CH2CN