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Zearalenone

Product Name
Zearalenone
CAS No.
17924-92-4
Chemical Name
Zearalenone
Synonyms
ZON;ZEN;RAL;ZENONE;toxinf2;f-2toxin;(3S,11E)-;nci-c50226;earalenone;ZEARALENONE
CBNumber
CB4131407
Molecular Formula
C18H22O5
Formula Weight
318.36
MOL File
17924-92-4.mol
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Zearalenone Property

Melting point:
164-165°C
alpha 
25546 -170.5° (c = 1.0 in CH3OH)
Boiling point:
377.53°C (rough estimate)
Density 
1.1270 (rough estimate)
refractive index 
1.6120 (estimate)
Flash point:
6 °C
storage temp. 
2-8°C
form 
neat
pka
7.58±0.40(Predicted)
Merck 
13,10169
BRN 
1350216
InChIKey
MBMQEIFVQACCCH-QBODLPLBSA-N
CAS DataBase Reference
17924-92-4(CAS DataBase Reference)
EPA Substance Registry System
Zearalenone (17924-92-4)
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Safety

Hazard Codes 
C,Xn,F
Risk Statements 
34-62-63-36-20/21/22-11
Safety Statements 
26-36/37/39-45-36-16-36/37
RIDADR 
UN 3261 8/PG 2
WGK Germany 
3
RTECS 
DM2550000
10
HS Code 
29322090
Hazardous Substances Data
17924-92-4(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H302Harmful if swallowed

H312Harmful in contact with skin

H314Causes severe skin burns and eye damage

H319Causes serious eye irritation

H332Harmful if inhaled

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P310Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CRM46916
Product name
Zearalenone solution
Purity
certified reference material, 50?μg/mL in acetonitrile, ampule of 1?mL
Packaging
1 mL
Price
$86.6
Updated
2021/12/16
Sigma-Aldrich
Product number
34126
Product name
Zearalenone solution
Purity
100 μg/mL in acetonitrile, analytical standard
Packaging
2ml
Price
$381
Updated
2021/12/16
Sigma-Aldrich
Product number
32939
Product name
Zearalenone
Purity
reference material
Packaging
5mg
Price
$606
Updated
2021/12/16
Sigma-Aldrich
Product number
Z2125
Product name
Zearalenone
Purity
fungal mycotoxin
Packaging
10mg
Price
$140
Updated
2021/03/22
Sigma-Aldrich
Product number
Z2125
Product name
Zearalenone
Purity
fungal mycotoxin
Packaging
25mg
Price
$274
Updated
2021/03/22
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Zearalenone Chemical Properties,Usage,Production

Chemical Properties

Crystalline Solid

Uses

Zearalenone is a resorcylic acid lactone produced by a number of Fusarium sp.. Zearalenone acts as a non-steroidal estrogen, binding to estrogen receptor and is uterotropic. Zearalenone induces reproductive problems in animals and, in some animal models, is thought to be a primary initiator of hepatic tumours. In vivo, zearalenone undergoes metabolic reduction to the more estrogenic zearalenol. Contamination of grains, notably maize, by Fusarium species gives rise to high levels of zearalenone and is regarded as an important food quality issue for both humans and animal health.

Uses

A phytoestrogenic mycotoxin and ER activator

Uses

Estrogenic mycotoxin produced by Fusarium fungi commonly found in grains. One of a group of compounds known as resorcylic acid lactones

Definition

ChEBI: A macrolide comprising a fourteen-membered lactone fused to 1,3-dihydroxybenzene; a potent estrogenic metabolite produced by some Giberella species.

General Description

White microcrystals or white powder.

Air & Water Reactions

Zearalenone may be sensitive to prolonged exposure to air. Insoluble in water.

Reactivity Profile

Zearalenone is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides. Zearalenone may be incompatible with alkalis.

Fire Hazard

Flash point data for Zearalenone are not available. Zearalenone is probably combustible.

Biochem/physiol Actions

Zearalenone, a fungal mycotoxin produced by Fusarium, binds the estrogen receptor (ER) and is uterotropic in the newborn rat. It is a common contaminant in cereal grain used for animal and human food, and exerts an estrogenic activity that modulates/disrupts endocrine function in animals and possibly humans.

Metabolic pathway

When zearalenone is subjected to microbial transformation by a fungus, Gliocladium roseum, it is converted to a 1 : 1 mixture of 1-(3,5-dihydroxyphenyl)- 10 0 -hydroxy-1-undecen-6'-one and 1-(3,5- dihydroxyphenyl)-6'-hydroxy-1-undecen-10'-one.

Zearalenone Preparation Products And Raw materials

Raw materials

Preparation Products

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Zearalenone Suppliers

Huzhou fuhe Rui biological medicine co., ltd
Tel
;
Email
953022190@qq.com;953022190@qq.com
Country
China
ProdList
384
Advantage
58
ShangHai Biochempartner Co.,Ltd
Tel
137-20134139-
Fax
QQ:2853530911
Email
candy@biochempartner.com
Country
China
ProdList
8021
Advantage
62
Beijing OKA biological technology co., LTD
Tel
010-62971590-
Fax
010-62340519
Email
3462612863@qq.com
Country
China
ProdList
10589
Advantage
58
Zhuhai Anzhe Biotechnology Co,Ltd.
Tel
0756-7790054-
Email
2928847974@qq.com
Country
China
ProdList
2607
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2926
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833-
Fax
86-10-82849933
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15877
Advantage
69
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078;021-50426030
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
10006
Advantage
60
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32358
Advantage
50
Syntechem Co.,Ltd
Tel
Please Email
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
13009
Advantage
57
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View Lastest Price from Zearalenone manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Zearalenone 17924-92-4
Price
US $0.00-0.00/KG
Min. Order
100g
Purity
99.0%+
Supply Ability
100 tons
Release date
2020-01-19
Career Henan Chemical Co
Product
Zearalenone 17924-92-4
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
1000kg
Release date
2018-12-25

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