Zearalenone
- Product Name
- Zearalenone
- CAS No.
- 17924-92-4
- Chemical Name
- Zearalenone
- Synonyms
- ZEN;ZON;(s)-zearalenone;RAL;(-)-Zearalenone;[S-(E)]-3,4,5,6,9,10-hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione;ZENONE;toxinf2;f-2toxin;(3S,11E)-
- CBNumber
- CB4131407
- Molecular Formula
- C18H22O5
- Formula Weight
- 318.36
- MOL File
- 17924-92-4.mol
Zearalenone Property
- Melting point:
- 164-165°C
- alpha
- 25546 -170.5° (c = 1.0 in CH3OH)
- Boiling point:
- 377.53°C (rough estimate)
- Density
- 1.1270 (rough estimate)
- refractive index
- 1.6120 (estimate)
- Flash point:
- 6 °C
- storage temp.
- 2-8°C
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:7): 0.12 mg/ml; Ethanol: 20 mg/ml
- pka
- 7.58±0.40(Predicted)
- form
- Solid
- color
- Off-white
- Merck
- 13,10169
- BRN
- 1350216
- InChIKey
- MBMQEIFVQACCCH-QBODLPLBSA-N
- LogP
- 3.830 (est)
- CAS DataBase Reference
- 17924-92-4(CAS DataBase Reference)
- EPA Substance Registry System
- Zearalenone (17924-92-4)
Safety
- Hazard Codes
- C,Xn,F
- Risk Statements
- 34-62-63-36-20/21/22-11
- Safety Statements
- 26-36/37/39-45-36-16-36/37
- RIDADR
- UN 3261 8/PG 2
- WGK Germany
- 3
- RTECS
- DM2550000
- F
- 10
- HS Code
- 29322090
- Hazardous Substances Data
- 17924-92-4(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P202Do not handle until all safety precautions have been read and understood.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CRM46916
- Product name
- Zearalenone solution
- Purity
- certified reference material, 50?μg/mL in acetonitrile, ampule of 1?mL
- Packaging
- 1mL
- Price
- $111
- Updated
- 2024/03/01
- Product number
- 34126
- Product name
- Zearalenone solution
- Purity
- 100 μg/mL in acetonitrile, analytical standard
- Packaging
- 2ml
- Price
- $488
- Updated
- 2024/03/01
- Product number
- 32939
- Product name
- Zearalenone
- Purity
- reference material
- Packaging
- 5mg
- Price
- $689
- Updated
- 2022/05/15
- Product number
- 11353
- Product name
- Zearalenone
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $39
- Updated
- 2024/03/01
- Product number
- 11353
- Product name
- Zearalenone
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $73
- Updated
- 2024/03/01
Zearalenone Chemical Properties,Usage,Production
Chemical Properties
Crystalline Solid
Uses
Zearalenone is a resorcylic acid lactone produced by a number of Fusarium sp.. Zearalenone acts as a non-steroidal estrogen, binding to estrogen receptor and is uterotropic. Zearalenone induces reproductive problems in animals and, in some animal models, is thought to be a primary initiator of hepatic tumours. In vivo, zearalenone undergoes metabolic reduction to the more estrogenic zearalenol. Contamination of grains, notably maize, by Fusarium species gives rise to high levels of zearalenone and is regarded as an important food quality issue for both humans and animal health.
Uses
A phytoestrogenic mycotoxin and ER activator
Uses
Estrogenic mycotoxin produced by Fusarium fungi commonly found in grains. One of a group of compounds known as resorcylic acid lactones
Definition
ChEBI: A macrolide comprising a fourteen-membered lactone fused to 1,3-dihydroxybenzene; a potent estrogenic metabolite produced by some Giberella species.
General Description
White microcrystals or white powder.
Air & Water Reactions
Zearalenone may be sensitive to prolonged exposure to air. Insoluble in water.
Reactivity Profile
Zearalenone is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides. Zearalenone may be incompatible with alkalis.
Fire Hazard
Flash point data for Zearalenone are not available. Zearalenone is probably combustible.
Biochem/physiol Actions
Zearalenone, a fungal mycotoxin produced by Fusarium, binds the estrogen receptor (ER) and is uterotropic in the newborn rat. It is a common contaminant in cereal grain used for animal and human food, and exerts an estrogenic activity that modulates/disrupts endocrine function in animals and possibly humans.
Metabolic pathway
When zearalenone is subjected to microbial transformation by a fungus, Gliocladium roseum, it is converted to a 1 : 1 mixture of 1-(3,5-dihydroxyphenyl)- 10 0 -hydroxy-1-undecen-6'-one and 1-(3,5- dihydroxyphenyl)-6'-hydroxy-1-undecen-10'-one.
storage
-20°C
Zearalenone Preparation Products And Raw materials
Raw materials
Preparation Products
Zearalenone Suppliers
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View Lastest Price from Zearalenone manufacturers
- Product
- Zearalenone 17924-92-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 100g
- Purity
- 99.0%+
- Supply Ability
- 100 tons
- Release date
- 2020-01-19
- Product
- Zearalenone 17924-92-4
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 95%-99%
- Supply Ability
- 1000kg
- Release date
- 2018-12-25