S-(2-thiopyridyl)mercaptopropionohydrazide
- Product Name
- S-(2-thiopyridyl)mercaptopropionohydrazide
- CAS No.
- 115616-51-8
- Chemical Name
- S-(2-thiopyridyl)mercaptopropionohydrazide
- Synonyms
- 3-(2-Pyridyldisulfanyl)propanehydrazide;3-(pyridin-2-yldisulfanyl)propanehydrazide;S-(2-thiopyridyl)mercaptopropionohydrazide;3-(2-Pyridyldithio)propionylhydrazide(PDPH);Propanoic acid, 3-(2-pyridinyldithio)-, hydrazide
- CBNumber
- CB41322297
- Molecular Formula
- C8H11N3OS2
- Formula Weight
- 229.32
- MOL File
- 115616-51-8.mol
S-(2-thiopyridyl)mercaptopropionohydrazide Property
- Melting point:
- 87-90°C
- Boiling point:
- 463.6±41.0 °C(Predicted)
- Density
- 1.35±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 12.81±0.35(Predicted)
- color
- White
- Stability:
- Light Sensitive
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 803480
- Product name
- PDPH (3-(2-pyridyldithio)propionyl hydrazide)
- Packaging
- 50MG
- Price
- $335
- Updated
- 2025/07/31
- Product number
- P993040
- Product name
- 3-(2-Pyridyldithio)propanoicAcidHydrazide
- Packaging
- 5mg
- Price
- $140
- Updated
- 2021/12/16
- Product number
- CHM0009632
- Product name
- 3-(2-PYRIDYLDITHIO)PROPANOIC ACID HYDRAZIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $774.4
- Updated
- 2021/12/16
- Product number
- CHM0009632
- Product name
- 3-(2-PYRIDYLDITHIO)PROPANOIC ACID HYDRAZIDE
- Purity
- 95.00%
- Packaging
- 50MG
- Price
- $1871.1
- Updated
- 2021/12/16
S-(2-thiopyridyl)mercaptopropionohydrazide Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
A fluorescent sulfhydryl active reagent.
General Description
The PDPH is a heterobifunctional crosslinker containing sulfhydryl-reactive pyridyldithiol and carbonyl-reactive hydrazide moieties. Pyridyldithiols react with free sulfhydryls (-SH) to form disulfide bonds. Hydrazide groups react with carbonyls (aldehydes and ketones) to form stable hydrazone bonds. Aldehyde groups can be created by periodate-oxidation of sialic acid and other sugar components of glycoprotein polysaccharides. Thus, PDPH is useful for conjugating glycoproteins and sulfhydryl-containing peptides or proteins. Likewise, PDPH is useful as a sulfhydryl-addition reagent for glycoproteins and other carbohydrates; after reaction of the hydrazide to an oxidized carbohydrate, the pyridyldithiol group can be cleaved by a reducing agent to expose a sulfhydryl group. Yet another application for PDPH is to react the primary amine of the hydrazide moiety to a carboxyl group using the crosslinker EDC.
reaction suitability
reagent type: cross-linking reagent
S-(2-thiopyridyl)mercaptopropionohydrazide Preparation Products And Raw materials
Raw materials
Preparation Products
S-(2-thiopyridyl)mercaptopropionohydrazide Suppliers
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