(4-Pyrazol-1-ylphenyl)methanol

Product Name: (4-Pyrazol-1-ylphenyl)methanol
CAS No.: 143426-49-7
Chemical Name: (4-Pyrazol-1-ylphenyl)methanol
Synonyms: CPD2800-A2;BUTTPARK 98\50-44;RARECHEM AL BD 1319;4-Pyrazol-1-ylbenzyl alcohol;4-(1-PYRAZOLYL)BENZYLALCOHOL;(4-PYRAZOL-1-YL-PHENYL)METHANOL;[4-(1-Pyrazolyl)phenyl]Methanol;4-(1H-Pyrazol-1-yl)benzyl alcohol;1-[4-Hydroxymethyl)phenyl]pyrazole;(4-PYRAZOL-1-YL-PHENYL)METHANOL 95%
CBNumber: CB4133087
Molecular Formula: C10H10N2O
Formula Weight: 174.2
MOL File: 143426-49-7.mol

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(4-Pyrazol-1-ylphenyl)methanol Property

Melting point:: 76-80°C
Boiling point:: 324.3±25.0 °C(Predicted)
Density: 1.16±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 14.25±0.10(Predicted)
Appearance: White to off-white Solid
CAS DataBase Reference: 143426-49-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39
HazardClass: IRRITANT
HS Code: 2933499090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC

Product number: P846903
Product name: [4-(1H-Pyrazol-1-yl)phenyl]methanol
Packaging: 10mg
Price: $45
Updated: 2021/12/16

TRC

Product number: P846903
Product name: [4-(1H-Pyrazol-1-yl)phenyl]methanol
Packaging: 100mg
Price: $75
Updated: 2021/12/16

Apolloscientific

Product number: OR23294
Product name: [4-(1H-Pyrazol-1-yl)phenyl]methanol
Packaging: 5g
Price: $58
Updated: 2021/12/16

Apolloscientific

Product number: OR23294
Product name: [4-(1H-Pyrazol-1-yl)phenyl]methanol
Packaging: 1g
Price: $16
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H01-1-U8
Product name: 4-(1H-Pyrazol-1-yl)benzyl alcohol
Packaging: 1g
Price: $39
Updated: 2021/12/16

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(4-Pyrazol-1-ylphenyl)methanol Chemical Properties,Usage,Production

Synthesis

143426-47-5

143426-49-7

General procedure for the synthesis of 4-pyrazol-1-ylbenzyl alcohol from methyl 4-(1H-pyrazol-1-yl)benzoate: G) Synthesis of [4-(1H-pyrazol-1-yl)phenyl]methanol To a solution of ethyl 4-(1H-pyrazol-1-yl)benzoate (73.7 g) in tetrahydrofuran (THF, 500 mL), sodium borohydride (19.5 g) and calcium chloride (56.8 g) were slowly added under cooling in an ice bath. The reaction mixture was stirred at room temperature for 16 h, followed by heating and refluxing for 2 days. After completion of the reaction, the reaction mixture was diluted with 1N hydrochloric acid and extracted with ethyl acetate (4 times). The organic layers were combined, washed with saturated brine and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure and the residue was washed with tert-butyl methyl ether to give 4-pyrazol-1-ylbenzyl alcohol (49.6 g) as a white solid. Product characterization: 1H NMR (400 MHz, CDCl3) δ 2.79 (1H, br s), 4.68 (2H, s), 6.45 (1H, t, J = 2.0 Hz), 7.38 (2H, d, J = 7.6 Hz), 7.61 (2H, d, J = 8.4 Hz), 7.70 (1H, s), 7.89 (1H, d, J = 1.6 Hz).

References

[1] European Journal of Medicinal Chemistry, 1992, vol. 27, # 3, p. 219 - 228
[2] Patent: WO2015/163485, 2015, A1. Location in patent: Paragraph 0387

(4-Pyrazol-1-ylphenyl)methanol Preparation Products And Raw materials

Raw materials

Preparation Products

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(4-Pyrazol-1-ylphenyl)methanol Suppliers

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View Lastest Price from (4-Pyrazol-1-ylphenyl)methanol manufacturers

Career Henan Chemical Co

Product: (4-Pyrazol-1-ylphenyl)methanol 143426-49-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2019-12-25

143426-49-7, (4-Pyrazol-1-ylphenyl)methanolRelated Search:

Methanol 4-Methoxybenzyl alcohol Phenyl salicylate Triphenylmethanol 2-Methyl-1-phenyl-2-propanol Benzyl alcohol Diphenyl ether PHENYL VALERATE PHENYL RESIN Phenylacetic acid 4-(1H-PYRAZOL-1-YL)BENZOIC ACID p-(2H-Indazol-2-yl)-benzoic acid METHYL 4-(1H-PYRAZOL-1-YL)BENZENECARBOXYLATE 4-[4-(4-CHLOROPHENYL)-1H-PYRAZOL-1-YL]BENZOIC ACID 4-(4-PYRIMIDIN-4-YL-1H-PYRAZOL-1-YL)BENZOICACID 4-(5-AMINO-3-METHYL-PYRAZOL-1-YL)-BENZOIC ACID 4-(5-AMINO-3-METHYL-PYRAZOL-1-YL)-BENZOIC ACID HYDROCHLORIDE (4-Pyrazol-1-ylphenyl)methanol

BUTTPARK 98\50-44

RARECHEM AL BD 1319

(4-PYRAZOL-1-YL-PHENYL)METHANOL

4-(1-PYRAZOLYL)BENZYLALCOHOL

[4-(1H-PYRAZOL-1-YL)PHENYL]METHANOL

4-Pyrazol-1-ylbenzyl alcohol

(4-PYRAZOL-1-YL-PHENYL)METHANOL 95%

[4-(1-Pyrazolyl)phenyl]Methanol

4-(1H-Pyrazol-1-yl)benzyl alcohol, 1-[4-(Hydroxymethyl)phenyl]-1H-pyrazole

4-(1H-Pyrazol-1-yl)benzyl alcohol

1-[4-Hydroxymethyl)phenyl]pyrazole

4-(1H-pyrazol-1-yl)-benzenemethanol

CPD2800-A2

Benzenemethanol, 4-(1H-pyrazol-1-yl)-

143426-49-7

Pyrazole series

Alcohols and Derivatives

Heterocycles