geninthiocin

Product Name: geninthiocin
CAS No.: 158792-27-9
Chemical Name: geninthiocin
Synonyms: geninthiocin;Geninthiocin A;PubChem ID: 16129809;14-DeMethylberinaMycin;Alaninamide, L-threonyl-2-[(1Z)-1-amino-1-propen-1-yl]-4-oxazolecarbonyl-2,3-didehydroalanyl-3-methyl-L-threonyl-2-(1-aminoethenyl)-5-methyl-4-oxazolecarbonyl-2,3-didehydroalanyl-6-[2-(1-aminoethenyl)-4-oxazolyl]-5-(4-carboxy-2-thiazolyl)-2-pyridinecarbonyl-2,3-didehydroalanyl-2,3-didehydro-, (7→1)-...
CBNumber: CB41333237
Molecular Formula: C50H49N15O15S
Formula Weight: 1132.08
MOL File: 158792-27-9.mol

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geninthiocin Property

Density: 1.54±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: soluble; DMSO: soluble; Ethanol: slightly soluble
form: White to off-white amorphous powder.
pka: 10.01±0.60(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 28125
Product name: Geninthiocin A
Packaging: 500μg
Price: $323
Updated: 2024/03/01

Cayman Chemical

Product number: 28125
Product name: Geninthiocin A
Packaging: 2.5mg
Price: $1127
Updated: 2024/03/01

TRC

Product number: G350058
Product name: Geninthiocin
Packaging: 500μg
Price: $295
Updated: 2021/12/16

Usbiological

Product number: G2024-66
Product name: Geninthiocin
Packaging: 500ug
Price: $523
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0019325
Product name: GENINTHIOCIN
Purity: 95.00%
Packaging: 0.5MG
Price: $549
Updated: 2021/12/16

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geninthiocin Chemical Properties,Usage,Production

Description

Geninthiocin A is a cyclic thiopeptide bacterial metabolite originally isolated from Streptomyces sp. DD84. It is active against a variety of Gram-positive bacteria (MICs = 0.2-4 μg/ml), the Gram-negative bacterium C. violaceum (MIC = 19 μg/ml), and the fungus M. hiemalis (MIC = 38 μg/ml). Geninthiocin A also induces tipA promoter transcription with a minimum induction concentration of 1.2 ng/ml.

Uses

Geninthiocin, a thiopeptide antibiotic isolated from a Streptomyces sp., is a potent activator of the tipA gene, a bacterial transcription regulator involved in multidrug resistance. Geninthiocin displays a 10-fold selectivity for bacteria over mammalian cells lines, whereas the related dedialanyl geninthiocin shows the reverse selectivity. Geninthiocin is closely related to siomycin, a recently discovered inhibitor of oncogenic transcription factor, FoxM1.

Uses

Geninthiocin is a thiopeptide antibiotic tipA gene activator.

geninthiocin Preparation Products And Raw materials

Raw materials

Preparation Products

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geninthiocin Suppliers

China 21 France 1 Germany 1 United Kingdom 1 United States 5 Global 29

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

Lynnchem

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Email: info@lynnchem.com
Country: China
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Novachemistry

Tel: 44-20819178-90 02081917890
Fax: (0)2080432064
Email: info@novachemistry.com
Country: United Kingdom
ProdList: 4381
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Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57412
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

BOC Sciences

Tel: 16314854226; +16314854226
Email: inquiry@bocsci.com
Country: United States
ProdList: 19741
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11217
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Meng Cheng Technology (Shanghai) Co., LTD

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Email: sales@mitachieve.com
Country: China
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Zhejiang Huida Biotech Co., LTD

Tel: 0571-89903882 13626641628
Email: jiangnan@huidabiotech.com
Country: China
ProdList: 3656
Advantage: 58

158792-27-9, geninthiocinRelated Search:

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geninthiocin

14-DeMethylberinaMycin

PubChem ID: 16129809

Geninthiocin A

Alaninamide, L-threonyl-2-[(1Z)-1-amino-1-propen-1-yl]-4-oxazolecarbonyl-2,3-didehydroalanyl-3-methyl-L-threonyl-2-(1-aminoethenyl)-5-methyl-4-oxazolecarbonyl-2,3-didehydroalanyl-6-[2-(1-aminoethenyl)-4-oxazolyl]-5-(4-carboxy-2-thiazolyl)-2-pyridinecarbonyl-2,3-didehydroalanyl-2,3-didehydro-, (7→1)-...

158792-27-9

C50H49N15O15S