ChemicalBook > CAS DataBase List > KARANJIN

KARANJIN

Product Name
KARANJIN
CAS No.
521-88-0
Chemical Name
KARANJIN
Synonyms
3-Methoxy-2-phenyl-4H-furo[2,3-h]chromen-4-one;KARNJIN;Kranjin;KARANJIN;NSC254030;NSC 335755;NSC 254030;NSC-254030;Karanjin-RM;Cysteinic acid
CBNumber
CB4134736
Molecular Formula
C18H12O4
Formula Weight
292.29
MOL File
521-88-0.mol
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KARANJIN Property

Melting point:
156°C
Boiling point:
463.0±45.0 °C(Predicted)
Density 
1.36
storage temp. 
2-8°C
solubility 
Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly)
form 
Solid
Specific Gravity
1.495
color 
White to Off-White
InChI
InChI=1S/C18H12O4/c1-20-18-15(19)13-7-8-14-12(9-10-21-14)17(13)22-16(18)11-5-3-2-4-6-11/h2-10H,1H3
InChIKey
LKPQNZRGGNOPPU-UHFFFAOYSA-N
SMILES
C1(C2=CC=CC=C2)OC2C3C=COC=3C=CC=2C(=O)C=1OC
LogP
3.290 (est)
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Safety

RTECS 
DX1500000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FM68027
Product name
Karanjin
Packaging
250mg
Price
$60
Updated
2021/12/16
Biosynth Carbosynth
Product number
FM68027
Product name
Karanjin
Packaging
500mg
Price
$100
Updated
2021/12/16
AK Scientific
Product number
7332AB
Product name
3-Methoxy-2-phenyl-4H-furo[2,3-h]chromen-4-one
Packaging
250mg
Price
$131
Updated
2021/12/16
Biosynth Carbosynth
Product number
FM68027
Product name
Karanjin
Packaging
1g
Price
$170
Updated
2021/12/16
AK Scientific
Product number
7332AB
Product name
3-Methoxy-2-phenyl-4H-furo[2,3-h]chromen-4-one
Packaging
1g
Price
$279
Updated
2021/12/16
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KARANJIN Chemical Properties,Usage,Production

Chemical Properties

Needle-shaped crystal, soluble in methanol, ethanol, DMSO and other organic solvents, derived from water yellow skin, water Luo umbrella, water flow bean Pongamia pinnata, Mori fish vine Derris mollis. .

Uses

Aquaxanthin has an anti-tuberculosis effect.

Definition

ChEBI: Karanjin is an extended flavonoid.

Biological Activity

Karanjin is the main active furanoflavonol component in Fordia cauliflora. It induces GLUT4 translocation in skeletal muscle cells by increasing AMPK, and induces cancer cell death through cell cycle arrest and promotes apoptosis.

in vivo

Karanjin (50, 100 mg/kg, p.o., 6 h) reduces the blood glucose level of Streptozotocin (HY-13753)-induced diabetic rats[1].
Karanjin (20 mg/kg/d, p.o., 21 d) reduces joint injury and cartilage damage along with edema and erythema in the AIA model rats[1].
Karanjin (10, 20 mg/kg/d, p.o., 14 d) significantly decreases serum ACP, ALP and TNFα levels in the AIA model rats [1].
Karanjin (25 or 50 mg/kg/d, p.o. or i.g., 8 d) improved learning and memory in Diazepam-induced amnesia mice[1].

Animal Model:Streptozotocin-induced diabetic rats[1]
Dosage:50, 100 mg/kg
Administration:Oral gavage (p.o.), wait for 6h
Result:Lowered the blood glucose level by 11.7% and 20.7% at 50 and 100 mg/kg gavage.
Animal Model:Adjuvant induced arthritis model (AIA) Wistar strain male albino rats[1]
Dosage:10, 20 mg/kg/d
Administration:Oral gavage (p.o.), 14 d for serum assay, 21 d for histological examination
Result:Reduced articular cartilage damage, cellular infiltration in the articular cartilage and spongy bone damage significantly. Decreased serum acid phosphatase, alkaline phosphatase levels and TNFα level markedly.
Animal Model:Diazepam-induced male swiss albino mice [1]
Dosage:25, 50 mg/kg/d
Administration:Oral gavage (p.o.) or Intraperitoneal injection (i.p.) for 8 d
Result:Decreased the transfer latency on all the observation days, significantly reversed diazepam-induced amnesia, indicating improved learning and memory in treated mice.

KARANJIN Preparation Products And Raw materials

Raw materials

Preparation Products

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KARANJIN Suppliers

Canada 1 China 113 Germany 3 India 10 Japan 2 Switzerland 1 The Netherlands 1 United Kingdom 7 United States 13 USA 1 Global 152
Huzhou ZhanShu Biotechnology Co.,Ltd
Tel
0572-8889530 18167260939
Email
zsubio@163.com
Country
China
ProdList
392
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15883
Advantage
64
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3988
Advantage
66
Cheng Du Pufeide Biotechnology Co., Ltd.
Tel
028-82610909 13388174823
Fax
8171-1798
Email
scglp@glp-china.com
Country
China
ProdList
1064
Advantage
58
Chengdu Herbpurify Co.Ltd.
Tel
2355253622; 18981954830
Fax
086-28-85377358
Email
2355253622@qq.com;
Country
China
ProdList
1103
Advantage
58
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9637
Advantage
58
Shanghai Aspire Biological Technology Co., Ltd.
Tel
021-61317773
Fax
021-61486878
Email
sales@aspirebio.com
Country
China
ProdList
2880
Advantage
58
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View Lastest Price from KARANJIN manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
KARANJIN 521-88-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-03-31
R&D Scientific Inc.
Product
Karanjin 521-88-0
Price
US $4500.00/g
Min. Order
1g
Purity
97 %
Supply Ability
500 Kg
Release date
2024-08-23
Shaanxi Dideu Medichem Co. Ltd
Product
karanjin 521-88-0
Price
US $0.10/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000Tons
Release date
2024-08-05

521-88-0, KARANJINRelated Search:

MEDICAGOL GARDENIN B 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one hydroxygenkwanin PONCIRIN MOSLOFLAVONE Quercetin-7-O-β-D-glucopyranoside KARANJIN KARANJIN(P) 1-Benzofuran-5-carbaldehyde 3-METHOXYFLAVONE 1-(2-METHOXYPHENYL)ETHANOL 5-methylbenzofuran 1-(4-HYDROXYBENZOFURAN-5-YL)ETHANONE Karanjol 1-(4-METHOXYBENZOFURAN-5-YL)ETHANONE KARANJIN(RG) KARANJIN(REAGENT / STANDARD GRADE)

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