ChemicalBook > CAS DataBase List > BOC-D-PRO-OME

BOC-D-PRO-OME

Product Name
BOC-D-PRO-OME
CAS No.
73323-65-6
Chemical Name
BOC-D-PRO-OME
Synonyms
(2R)-pyrroL;BOC-D-PRO-OME;BOC-D-PYRD(2)-OME;idine-1,2-dicarboxyL;Boc-D-methyl proline;BOC-D-PRO-OME USP/EP/BP;Bok - D - Methyl proline;BOC-D-PROLINE METHYL ESTER;N-Boc-D-proline methyl este;N-BOC-D-PROLINE METHYL ESTER
CBNumber
CB4138390
Molecular Formula
C11H19NO4
Formula Weight
229.27
MOL File
73323-65-6.mol
More
Less

BOC-D-PRO-OME Property

Boiling point:
288.6±33.0 °C(Predicted)
Density 
1.120±0.06 g/cm3(Predicted)
refractive index 
1.4510-1.4550
storage temp. 
Sealed in dry,2-8°C
solubility 
Soluble in DMSO.
pka
-3.35±0.40(Predicted)
form 
Oil
color 
Clear Colourless
optical activity
59.8°(C=0.01g/ml MEOH)
InChI
InChI=1S/C11H19NO4/c1-11(2,3)16-10(14)12-7-5-6-8(12)9(13)15-4/h8H,5-7H2,1-4H3/t8-/m1/s1
InChIKey
WVDGSSCWFMSRHN-MRVPVSSYSA-N
SMILES
N1(C(OC(C)(C)C)=O)CCC[C@@H]1C(OC)=O
CAS DataBase Reference
73323-65-6(CAS DataBase Reference)
More
Less

Safety

HazardClass 
IRRITANT
HS Code 
2933998090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H311Toxic in contact with skin

H314Causes severe skin burns and eye damage

H371May cause damage to organs

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P391Collect spillage. Hazardous to the aquatic environment

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
B4787
Product name
N-(tert-Butoxycarbonyl)-D-proline Methyl Ester
Purity
>98.0%(GC)
Packaging
1g
Price
$26
Updated
2025/07/31
TCI Chemical
Product number
B4787
Product name
N-(tert-Butoxycarbonyl)-D-proline Methyl Ester
Purity
>98.0%(GC)
Packaging
5g
Price
$76
Updated
2025/07/31
TRC
Product number
B664205
Product name
N-Boc-D-prolineMethylEster
Packaging
10g
Price
$225
Updated
2021/12/16
Usbiological
Product number
265160
Product name
Boc-D-proline methyl ester
Packaging
500mg
Price
$333
Updated
2021/12/16
Chem-Impex
Product number
06651
Product name
Boc-D-proline methyl ester
Purity
≥ 99% (HPLC)
Packaging
5G
Price
$352
Updated
2021/12/16
More
Less

BOC-D-PRO-OME Chemical Properties,Usage,Production

Uses

N-Boc-D-proline methyl ester is an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff fields.

Synthesis

37784-17-1

74-88-4

73323-65-6

To a mixture of (R)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid (5.8 g, 27 mmol) and potassium carbonate (8.6 g, 62 mmol) in tetrahydrofuran (160 mL) was added iodomethane (4.0 mL, 65 mmol). The reaction mixture was heated to reflux for 17 hours and subsequently cooled to room temperature. The reaction mixture was filtered and the filtrate was concentrated under reduced pressure. The crude product was purified by automated column chromatography using petroleum ether/ethyl acetate (3:1, v/v) as eluent to afford (R)-1-tert-butyl 2-methyl pyrrolidine-1,2-dicarboxylate (6.0 g, 65% yield) as a yellow oil.

References

[1] Patent: WO2013/131018, 2013, A1. Location in patent: Page/Page column 38

BOC-D-PRO-OME Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

BOC-D-PRO-OME Suppliers

Americas 1 China 158 Europe 2 Germany 2 India 5 Japan 3 Switzerland 1 United Kingdom 1 United States 20 Global 193
Shanghai Chiral Chemicals Inc.
Tel
021-37285021 13472570865
Fax
86-021-51714507
Email
tym7xi@aliyun.com
Country
China
ProdList
308
Advantage
64
Shandong Lonyuta Pharmaceutical Technology Co., Ltd
Tel
0534-2152677 17862520650
Email
Fu_qx@inyelchem.com
Country
China
ProdList
274
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Shanghai Boc Chemical Co.,Ltd
Tel
021-34975603-808 18721111801
Fax
+86-21-34975602-805
Email
sales@bocpharma.com
Country
China
ProdList
1009
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Acesys Pharmatech
Tel
18860950986
Email
tangmanman@zenjipharma.com
Country
China
ProdList
1733
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9874
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Nanjing Redwood Fine Chemical Co., Ltd.
Tel
158-05183379 15805183379
Fax
86-025-58905816
Email
zjp@redwood.com.cn
Country
China
ProdList
217
Advantage
60
Porse Fine Chemical Co.,LTD
Tel
20-66003216 18666003216
Fax
+86-20-28069063
Email
info@porsefinechemical.com
Country
China
ProdList
1941
Advantage
62
Chengdu Firster Pharmaceutical Co., Ltd.
Tel
028-87078428 028-87074958
Fax
8772-8116
Email
chengzhenyong@cdfirster.com
Country
China
ProdList
2598
Advantage
60
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9637
Advantage
58
Sichuan Ampebiochem Co., Ltd.
Tel
028-65294243 13981822079;18682730901
Email
sales@ampebiochem.com
Country
China
ProdList
1000
Advantage
58
NINGBO INNO PHARMCHEM CO.,LTD.
Tel
86-574-27787657
Fax
86-574-27912196
Email
info@dearchem.com
Country
China
ProdList
4613
Advantage
58
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9793
Advantage
50
Shanghai Yongye Biotechnology Co., Ltd.
Tel
86-021-61559134 15921386130
Fax
021-55068248
Email
3423497944@qq.com
Country
China
ProdList
8144
Advantage
55
Shanghai Jovan Biochemical Technology Co. Ltd.
Tel
+86-021-61654350
Fax
+86-021-61654350
Email
1245958370@qq.com
Country
China
ProdList
2982
Advantage
50
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6479
Advantage
50
Nanjing Derno Pharmaceutical Technology Co., Ltd.
Tel
025-86957866 13952093866
Fax
025-68661287
Email
sales@dernopharm.com
Country
China
ProdList
932
Advantage
58
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Chengdu Chuangkecheng Biological Technology Co., Ltd.
Tel
028-028-0000000 13008177686
Fax
15928581901
Email
sales@ckcbiotech.com
Country
China
ProdList
904
Advantage
55
Tianjing Geneston Bio-tech Co.,Ltd.
Tel
022-60131465 18920720807
Fax
022-58558581
Email
zishan_1986@163.com
Country
China
ProdList
743
Advantage
58
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862，442785678，326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9627
Advantage
58
Henan CoreyChem Co., Ltd
Tel
0371-86658258
Fax
0371-60996044
Email
info@coreychem.com
Country
China
ProdList
10453
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9595
Advantage
55
Chengdu Huachun Technology Co., Ltd
Tel
400-1166-196 15982826727
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
14603
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Nanjing Peptide Biotech Ltd.
Tel
025-58361106-805 15951641583
Fax
025-58361106-806
Email
zhao.xu@njpeptide.com
Country
China
ProdList
9979
Advantage
55
Shanghai Kangman Biological Technology Co., Ltd.
Tel
18800375331
Fax
021-50908862
Email
kangmansales@163.com
Country
China
ProdList
7570
Advantage
55
Shanghai CR Corporation Limited
Tel
13062833949; 4006653949 4006653949
Fax
QQ: 2136646215
Email
fred.wen@crcorporation.cn
Country
China
ProdList
9757
Advantage
58
Adobe Chem Co., Ltd.
Tel
2332782371
Fax
QQ: 2332782371
Email
adobechem@qq.com
Country
China
ProdList
7980
Advantage
58
Taian Jiaye Biotechnology Co.Ltd
Tel
13127280945
Email
285424065@qq.com
Country
China
ProdList
9976
Advantage
55
Suzhou Ruichi Pharmaceutical Technology Co., Ltd.
Tel
0512-50152853
Fax
0512-50152853
Email
jjks1111@126.com
Country
China
ProdList
623
Advantage
58
Sichuan jiayinglai technology CO.,LTD
Tel
028-028-88457210 18190964009
Fax
QQ3213375147
Email
3054240163@qq.com
Country
China
ProdList
2293
Advantage
55
LinkChem Technology Co., Ltd.
Tel
021-58950110 13124863828
Fax
021-20922272
Email
sales@linkchem.cn
Country
China
ProdList
2998
Advantage
58
More
Less

View Lastest Price from BOC-D-PRO-OME manufacturers

Career Henan Chemical Co
Product
BOC-D-PRO-OME 73323-65-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
KG/T
Release date
2019-12-17

73323-65-6, BOC-D-PRO-OMERelated Search:

D-Proline N-Boc-D-proline 1-Boc-Pyrrolidine Boc-L-Pro-OMe (2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate BOC-D-PRO-OME 1-BOC-D-PYROGLUTAMIC ACID ETHYL ESTER (2R,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate N-BOC-TRANS-4-HYDROXY-D-PROLINE METHYL ESTER Boc-lle-Pro-OMe (R)-N-BOC-5-METHOXYCARBONYL-2-PYRROLIDINONE BOC-D-HYP-OTBU BOC-ALA-PRO-OME BOC-ILE-PRO-OME (2R,4S)-4-AMINO-1-BOC-PYRROLIDINE-2-CARBOXYLIC ACID METHYL ESTER (2R,4R)-4-AMINO-1-BOC-PYRROLIDINE-2-CARBOXYLIC ACID METHYL ESTER (R)-1-tert-butyl 2-methyl 4-oxopyrrolidine-1,2-dicarboxylate

  • BOC-D-PROLINE METHYL ESTER
  • BOC-D-PRO-OME
  • BOC-D-PYRD(2)-OME
  • R-1-BOC-PYRROLIDINE-2-CARBOXYLIC ACID METHYL ESTER
  • N-ALPHA-T-BUTOXYCARBONYL-D-PROLINE METHYL ESTER
  • N-ALPHA-T-BUTOXYCARBONYL-D-PYRROLIDINE-2-CARBOXYLIC ACID METHYL ESTER
  • N-tert-Butoxycarbonyl-D-Proline methyl ester
  • BOC-D-PROLINE METHYLESTER LIQUID
  • N-BOC-D-PROLINE METHYL ESTER
  • O1-tert-Butyl O2-methyl (2R)-pyrrolidine-1,2-dicarboxylate
  • 1-O-tert-butyl 2-O-methyl (2R)-pyrrolidine-1,2-dicarboxylate
  • (R)-Pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester
  • 1-tert-Butyl 2-methyl (2R)-pyrrolidine-1,2-dicarboxylate
  • N-Boc-D-proline methyl este
  • (R)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylate
  • (R)-1-tert-Butyl 2-Methyl pyrrolidine-1,2-dicarboxylate
  • 1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-diMethylethyl) 2-Methyl ester, (2R)-
  • Bok - D - Methyl proline
  • (R)-Boc-pyrrolidine-2-carboxylic acid methyl ester
  • Boc-D-proline methyl ester≥ 99% (HPLC)
  • N-(tert-Butoxycarbonyl)-D-proline Methyl Ester &gt
  • (2R)-pyrroL
  • idine-1,2-dicarboxyL
  • BOC-D-PRO-OME USP/EP/BP
  • 1-(1,1-Dimethylethyl) 2-methyl (2R)-1,2-pyrrolidinedicarboxylate
  • 1-(tert-butyl) 2-methyl (R)-pyrrolidine-1,2-dicarboxylate
  • Boc-D-methyl proline
  • N-Boc-D-proline methyl ester, 95%
  • O1-tert-Butyl O2-methyl (2R)-pyrrolidine-1,2-dicarboxylate - [B15682]
  • 73323-65-6
  • Pyrrole&Pyrrolidine&Pyrroline