ChemicalBook > CAS DataBase List > AQ 148

AQ 148

Product Name
AQ 148
CAS No.
178820-70-7
Chemical Name
AQ 148
Synonyms
AQ 148;(2S)-1-[(S)-benzamido-benzyl-methylazaniumyl]-3-[(2-methylpropan-2-yl)oxycarbonylamino]-4-phenylbutan-2-olate
CBNumber
CB41389698
Molecular Formula
C30H37N3O4
Formula Weight
503.639
MOL File
178820-70-7.mol
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CCH0039231
Product name
AQ 148
Purity
95.00%
Packaging
5MG
Price
$503.12
Updated
2021/12/16
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AQ 148 Chemical Properties,Usage,Production

Description

AQ 148 is a potent competitive inhibitor of HIV-1 PR.

Uses

AQ148 is a HIV-1 protease inhibitor (Ki=137 nM). The IC50 values ??of AQ148 for the inhibition of HIV-1, HIV-2 and SIV aspartic proteases are 1.5 μM, 3.4 μM and 5 μM, respectively[1].

References

[1] Rutenber, et al. "A new class of HIV-1 protease inhibitor: the crystallographic structure, inhibition and chemical synthesis of an aminimide peptide isostere." Bioorganic & medicinal chemistry 4.9 (1996): 1545-1558. DOI:10.1016/0968-0896(96)00147-2

AQ 148 Preparation Products And Raw materials

Raw materials

Preparation Products

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AQ 148 Suppliers

TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
29357
Advantage
58
TargetMol Chemicals Inc.
Tel
+17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
19961
Advantage
58