beta-endorphin (6-31)
- Product Name
- beta-endorphin (6-31)
- CAS No.
- 77761-27-4
- Chemical Name
- beta-endorphin (6-31)
- Synonyms
- beta-endorphin (6-31);6-31-β-Endorphin (human);b-Lipotropin (64-89) (huMan);4 β-Endorphin (6-31) (human);β-Lipotropin (64-89) (human);6-31-b-Endorphin (sheep),27-L-tyrosine-31-L-glutamic acid;6-31-β-Endorphin (sheep), 27-L-tyrosine-31-L-glutamic acid-;H-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu-OH
- CBNumber
- CB41394797
- Molecular Formula
- C131H218N34O40
- Formula Weight
- 2909.36
- MOL File
- 77761-27-4.mol
beta-endorphin (6-31) Property
- Boiling point:
- 2671.5±65.0 °C(Predicted)
- Density
- 1.294±0.06 g/cm3(Predicted)
- Sequence
- Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu
N-Bromosuccinimide Price
- Product number
- orb364362
- Product name
- Beta-Endorphin (6-31)
- Purity
- > 95%
- Packaging
- 1mg
- Price
- $479.4
- Updated
- 2021/12/16
- Product number
- orb364362
- Product name
- Beta-Endorphin (6-31)
- Purity
- > 95%
- Packaging
- 5mg
- Price
- $1016.6
- Updated
- 2021/12/16
- Product number
- orb364362
- Product name
- Beta-Endorphin (6-31)
- Purity
- > 95%
- Packaging
- 10mg
- Price
- $1518.1
- Updated
- 2021/12/16
beta-endorphin (6-31) Chemical Properties,Usage,Production
Uses
β-Endorphin, an endogenous opioid neuropeptide, is an opioid receptor agonist. β-Endorphin binds preferentially to μ-opioid receptors and is produced in certain neurons of the central and peripheral nervous system and is one of three endorphins produced in humans. β-Endorphin can be used to reduce stress and maintain homeostasis in the body and is involved in neurological pain perception regulation[1].
in vivo
β-Endorphin (0.03 to 1.00?μg/kg, i.p., once) impairs retention of a one-trial inhibitory avoidance task in a dose-dependent manner in male Swiss mice immediately post-training. Also, it works in the process of memory consolidation[1].
| Animal Model: | Adult male Swiss mice (22-25 g)[1] |
| Dosage: | 0.03, 0.10, 0.30 or 1.00 μg/kg |
| Administration: | i.p., once |
| Result: | Significantly impaired retention at the doses of 0.03 and 0.10?μg/kg while not significantly affect retention as compared with the control group at the two higher doses of 0.30 and 1.00?μg/kg , but tended to increase retention as compared with the dose of 0.10?μg/kg. Increased latencies to step-through at the two higher doses of 0.30 and 1.00?μg/kg but no effect at lower doses. |
References
[1] Introini IB, et al. The impairment of retention induced by beta-endorphin in mice may be mediated by a reduction of central cholinergic activity. Behav Neural Biol. 1984 Jul;41(2):152-63. DOI:10.1016/s0163-1047(84)90527-2
beta-endorphin (6-31) Preparation Products And Raw materials
Raw materials
Preparation Products
beta-endorphin (6-31) Suppliers
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- Country
- United States
- ProdList
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